"Protein Conformation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The characteristic 3-dimensional shape of a protein, including the secondary, supersecondary (motifs), tertiary (domains) and quaternary structure of the peptide chain. PROTEIN STRUCTURE, QUATERNARY describes the conformation assumed by multimeric proteins (aggregates of more than one polypeptide chain).
| Descriptor ID |
D011487
|
| MeSH Number(s) |
G02.111.570.820.709
|
| Concept/Terms |
Protein Conformation- Protein Conformation
- Conformation, Protein
- Conformations, Protein
- Protein Conformations
|
Below are MeSH descriptors whose meaning is more general than "Protein Conformation".
Below are MeSH descriptors whose meaning is more specific than "Protein Conformation".
This graph shows the total number of publications written about "Protein Conformation" by people in this website by year, and whether "Protein Conformation" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 2 | 2 |
| 2012 | 1 | 1 | 2 |
| 2013 | 0 | 2 | 2 |
| 2015 | 0 | 3 | 3 |
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 4 | 4 |
| 2021 | 0 | 4 | 4 |
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Below are the most recent publications written about "Protein Conformation" by people in Profiles.
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Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM. Nat Commun. 2021 08 10; 12(1):4817.
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Impact of single amino acid substitution on the structure and function of TANK-binding kinase-1. J Cell Biochem. 2021 10; 122(10):1475-1490.
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Structure-based investigation of MARK4 inhibitory potential of Naringenin for therapeutic management of cancer and neurodegenerative diseases. J Cell Biochem. 2021 10; 122(10):1445-1459.
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In silico comparative study of SARS-CoV-2 proteins and antigenic proteins in BCG, OPV, MMR and other vaccines: evidence of a possible putative protective effect. BMC Bioinformatics. 2021 Mar 26; 22(1):163.
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Common helical V1V2 conformations of HIV-1 Envelope expose the a4ß7 binding site on intact virions. Nat Commun. 2018 10 26; 9(1):4489.
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Structural Rearrangements Maintain the Glycan Shield of an HIV-1 Envelope Trimer After the Loss of a Glycan. Sci Rep. 2018 10 09; 8(1):15031.
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RK, the first scorpion peptide with dual disintegrin activity on a1ß1 and avß3 integrins. Int J Biol Macromol. 2018 Dec; 120(Pt B):1777-1788.
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Redox exchange of the disulfides of human two-domain CD4 regulates the conformational dynamics of each domain, providing insight into its mechanisms of control. Biochem Biophys Res Commun. 2018 03 04; 497(2):811-817.
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Macrovipecetin, a C-type lectin from Macrovipera lebetina venom, inhibits proliferation migration and invasion of SK-MEL-28 human melanoma cells and enhances their sensitivity to cisplatin. Biochim Biophys Acta Gen Subj. 2018 Mar; 1862(3):600-614.
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Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design. Nat Struct Mol Biol. 2016 Jan; 23(1):81-90.