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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Govender D, Moloko L, Papathanasopoulos M, Tumba N, Owen G, Calvey T. Ibogaine administration following repeated morphine administration upregulates myelination markers 2', 3'-cyclic nucleotide 3'-phosphodiesterase (CNP) and myelin basic protein (MBP) mRNA and protein expression in the internal capsule of Sprague Dawley rats. Front Neurosci. 2024; 18:1378841. PMID: 39114487; PMCID: PMC11303312.
      Citations:    
    2. Breiman RF, Demetriou G, Naidu G, Papathanasopoulos MA, Ruff P, Madhi SA. Shifting the center of gravity for addressing the rising cancer disease burden in Africa: A rationale for African-based integrative infectious diseases and oncology research. PLOS Glob Public Health. 2023; 3(5):e0001970. PMID: 37256858; PMCID: PMC10231805.
      Citations:    
    3. Tumba NL, Owen GR, Killick MA, Papathanasopoulos MA. Immunization with HIV-1 trimeric SOSIP.664 BG505 or founder virus C (FVCEnv) covalently complexed to two-domain CD4S60C elicits cross-clade neutralizing antibodies in New Zealand white rabbits. Vaccine X. 2022 Dec; 12:100222. PMID: 36262212; PMCID: PMC9573916.
      Citations: 1     
    4. Moshoette T, Papathanasopoulos MA, Killick MA. HIV-1 bispecific antibody iMab-N6 exhibits enhanced breadth but not potency over its parental antibodies iMab and N6. Virol J. 2022 09 07; 19(1):143. PMID: 36071449; PMCID: PMC9450465.
      Citations: 2     Fields:    Translation:HumansCells
    5. Tumba NL, Naicker P, Stoychev S, Killick MA, Owen GR, Papathanasopoulos MA. Covalent binding of human two-domain CD4 to an HIV-1 subtype C SOSIP.664 trimer modulates its structural dynamics. Biochem Biophys Res Commun. 2022 07 05; 612:181-187. PMID: 35550505.
      Citations:    Fields:    Translation:HumansCells
    6. Connell BJ, Hermans LE, Wensing AMJ, Schellens I, Schipper PJ, van Ham PM, de Jong DTCM, Otto S, Mathe T, Moraba R, Borghans JAM, Papathanasopoulos MA, Kruize Z, Venter FWD, Kootstra NA, Tempelman H, Tesselaar K, Nijhuis M. Immune activation correlates with and predicts CXCR4 co-receptor tropism switch in HIV-1 infection. Sci Rep. 2020 09 28; 10(1):15866. PMID: 32985522; PMCID: PMC7522993.
      Citations: 19     Fields:    Translation:HumansCells
    7. Moshoette T, Ali SA, Papathanasopoulos MA, Killick MA. Engineering and characterising a novel, highly potent bispecific antibody iMab-CAP256 that targets HIV-1. Retrovirology. 2019 11 08; 16(1):31. PMID: 31703699; PMCID: PMC6842167.
      Citations: 9     Fields:    Translation:HumansCells
    8. Palumbo PJ, Fogel JM, Hudelson SE, Wilson EA, Hart S, Hovind L, Piwowar-Manning E, Wallis C, Papathanasopoulos MA, Morgado MG, Saravanan S, Tripathy S, Eron JJ, Gallant JE, McCauley M, Gamble T, Hosseinipour MC, Kumarasamy N, Hakim JG, Pilotto JH, Kumwenda J, Akelo V, Godbole SV, Santos BR, Grinsztejn B, Panchia R, Chariyalertsak S, Makhema J, Badal-Faesen S, Chen YQ, Cohen MS, Eshleman SH. HIV Drug Resistance in Adults Receiving Early vs. Delayed Antiretroviral Therapy: HPTN 052. J Acquir Immune Defic Syndr. 2018 04 15; 77(5):484-491. PMID: 29293156; PMCID: PMC5844834.
      Citations: 4     Fields:    Translation:HumansCellsPHPublic Health
    9. Achilonu I, Elebo N, Hlabano B, Owen GR, Papathanasopoulos M, Dirr HW. An update on the biophysical character of the human eukaryotic elongation factor 1 beta: Perspectives from interaction with elongation factor 1 gamma. J Mol Recognit. 2018 07; 31(7):e2708. PMID: 29572982.
      Citations: 3     Fields:    Translation:HumansCells
    10. Owen GR, Le D, Stoychev S, Cerutti NM, Papathanasopoulos M. Redox exchange of the disulfides of human two-domain CD4 regulates the conformational dynamics of each domain, providing insight into its mechanisms of control. Biochem Biophys Res Commun. 2018 03 04; 497(2):811-817. PMID: 29470989.
      Citations: 2     Fields:    Translation:HumansCells
    11. Chikaonda T, Ketseoglou I, Nguluwe N, Krysiak R, Thengolose I, Nyakwawa F, Rosenberg NE, Stanley C, Mpunga J, Hoffman IF, Papathanasopoulos MA, Hosseinipour M, Scott L, Stevens W. Molecular characterisation of rifampicin-resistant Mycobacterium tuberculosis strains from Malawi. Afr J Lab Med. 2017; 6(2):463. PMID: 28879159; PMCID: PMC5523914.
      Citations: 8     
    12. Steegen K, Carmona S, Bronze M, Papathanasopoulos MA, van Zyl G, Goedhals D, MacLeod W, Sanne I, Stevens WS. Moderate Levels of Pre-Treatment HIV-1 Antiretroviral Drug Resistance Detected in the First South African National Survey. PLoS One. 2016; 11(12):e0166305. PMID: 27907009; PMCID: PMC5132262.
      Citations: 33     Fields:    Translation:HumansCells
    13. Steegen K, Bronze M, Papathanasopoulos MA, van Zyl G, Goedhals D, Van Vuuren C, Macleod W, Sanne I, Stevens WS, Carmona SC. Prevalence of Antiretroviral Drug Resistance in Patients Who Are Not Responding to Protease Inhibitor-Based Treatment: Results From the First National Survey in South Africa. J Infect Dis. 2016 Dec 15; 214(12):1826-1830. PMID: 27923946.
      Citations: 14     Fields:    Translation:HumansCells
    14. Steegen K, Bronze M, Papathanasopoulos MA, van Zyl G, Goedhals D, Variava E, MacLeod W, Sanne I, Stevens WS, Carmona S. HIV-1 antiretroviral drug resistance patterns in patients failing NNRTI-based treatment: results from a national survey in South Africa. J Antimicrob Chemother. 2017 01; 72(1):210-219. PMID: 27659733.
      Citations: 21     Fields:    Translation:HumansCells
    15. Moolla N, Killick M, Papathanasopoulos M, Capovilla A. Thioredoxin (Trx1) regulates CD4 membrane domain localization and is required for efficient CD4-dependent HIV-1 entry. Biochim Biophys Acta. 2016 09; 1860(9):1854-63. PMID: 27233453.
      Citations: 7     Fields:    Translation:HumansCells
    16. Owen GR, Channell JA, Forsyth VT, Haertlein M, Mitchell EP, Capovilla A, Papathanasopoulos M, Cerutti NM. Human CD4 Metastability Is a Function of the Allosteric Disulfide Bond in Domain 2. Biochemistry. 2016 Apr 19; 55(15):2227-37. PMID: 27009680.
      Citations: 5     Fields:    Translation:HumansCells
    17. Killick MA, Grant ML, Cerutti NM, Capovilla A, Papathanasopoulos MA. Env-2dCD4 S60C complexes act as super immunogens and elicit potent, broadly neutralizing antibodies against clinically relevant human immunodeficiency virus type 1 (HIV-1). Vaccine. 2015 Nov 17; 33(46):6298-306. PMID: 26432912.
      Citations: 3     Fields:    Translation:AnimalsCells
    18. Le Noury DA, Mosebi S, Papathanasopoulos MA, Hewer R. Functional roles of HIV-1 Vpu and CD74: Details and implications of the Vpu-CD74 interaction. Cell Immunol. 2015 Nov-Dec; 298(1-2):25-32. PMID: 26321123.
      Citations: 7     Fields:    Translation:HumansCells
    19. Tandon V, Yadav P, Sur S, Abbat S, Tiwari V, Hewer R, Papathanasopoulos MA, Raja R, Banerjea AC, Verma AK, Kukreti S, Bharatam PV. Design, Synthesis, and Biological Evaluation of 1,2-Dihydroisoquinolines as HIV-1 Integrase Inhibitors. ACS Med Chem Lett. 2015 Oct 08; 6(10):1065-70. PMID: 26487913; PMCID: PMC4601057.
      Citations: 5     
    20. Skhosana L, Steegen K, Bronze M, Lukhwareni A, Letsoalo E, Papathanasopoulos MA, Carmona SC, Stevens WS. High prevalence of the K65R mutation in HIV-1 subtype C infected patients failing tenofovir-based first-line regimens in South Africa. PLoS One. 2015; 10(2):e0118145. PMID: 25659108; PMCID: PMC4320083.
      Citations: 20     Fields:    Translation:HumansCells
    21. Killick M, Capovilla A, Papathanasopoulos MA. Generation and characterization of an HIV-1 subtype C transmitted and early founder virus consensus sequence. AIDS Res Hum Retroviruses. 2014 Oct; 30(10):1001-5. PMID: 25025284; PMCID: PMC4179916.
      Citations: 2     Fields:    Translation:HumansCells
    22. Harrison AT, Kriel FH, Papathanasopoulos MA, Mosebi S, Abrahams S, Hewer R. The evaluation of statins as potential inhibitors of the LEDGF/p75-HIV-1 integrase interaction. Chem Biol Drug Des. 2015 Mar; 85(3):290-5. PMID: 24954548.
      Citations: 3     Fields:    Translation:HumansCells
    23. Steegen K, Levin L, Ketseoglou I, Bronze M, Papathanasopoulos MA, Carmona S, Stevens W. High-level cross-resistance to didanosine observed in South African children failing an abacavir- or stavudine-based 1st-line regimen. PLoS One. 2014; 9(5):e97067. PMID: 24816790; PMCID: PMC4016228.
      Citations: 3     Fields:    Translation:HumansCells
    24. Cerutti N, Killick M, Jugnarain V, Papathanasopoulos M, Capovilla A. Disulfide reduction in CD4 domain 1 or 2 is essential for interaction with HIV glycoprotein 120 (gp120), which impairs thioredoxin-driven CD4 dimerization. J Biol Chem. 2014 Apr 11; 289(15):10455-10465. PMID: 24550395; PMCID: PMC4036167.
      Citations: 20     Fields:    Translation:HumansCells
    25. Ketseoglou I, Lukhwareni A, Steegen K, Carmona S, Stevens WS, Papathanasopoulos MA. Viral tropism and antiretroviral drug resistance in HIV-1 subtype C-infected patients failing highly active antiretroviral therapy in Johannesburg, South Africa. AIDS Res Hum Retroviruses. 2014 Mar; 30(3):289-93. PMID: 24224886; PMCID: PMC3938925.
      Citations: 6     Fields:    Translation:HumansCells
    26. Bronze M, Steegen K, Wallis CL, De Wolf H, Papathanasopoulos MA, Van Houtte M, Stevens WS, de Wit TR, Stuyver LJ, ART-A Consortium. HIV-1 phenotypic reverse transcriptase inhibitor drug resistance test interpretation is not dependent on the subtype of the virus backbone. PLoS One. 2012; 7(4):e34708. PMID: 22496845; PMCID: PMC3322145.
      Citations: 5     Fields:    Translation:HumansCells
    27. Mphahlele M, Papathanasopoulos M, Cinellu MA, Coyanis M, Mosebi S, Traut T, Modise R, Coates J, Hewer R. Modification of HIV-1 reverse transcriptase and integrase activity by gold(III) complexes in direct biochemical assays. Bioorg Med Chem. 2012 Jan 01; 20(1):401-7. PMID: 22104436.
      Citations: 3     Fields:    Translation:HumansCells
    28. Wallis CL, Venter WD, Stevens WS, Papathanasopoulos MA. Case report of the rare deletion at codon 69 of reverse transcriptase in a South African HIV-1 subtype C infected patient. Virus Genes. 2010 Dec; 41(3):358-60. PMID: 20890651.
      Citations:    Fields:    Translation:HumansCells
    29. Tiemessen CT, Shalekoff S, Meddows-Taylor S, Schramm DB, Papathanasopoulos M, Gray G, Sherman G, Coovadia A, Kuhn L. Natural killer cells that respond to human immunodeficiency virus type 1 (HIV-1) peptides are associated with control of HIV-1 infection. J Infect Dis. 2010 Nov 01; 202(9):1444-53. PMID: 20874516; PMCID: PMC3060333.
      Citations: 19     Fields:    Translation:HumansCells
    30. Cerutti N, Mendelow BV, Napier GB, Papathanasopoulos MA, Killick M, Khati M, Stevens W, Capovilla A. Stabilization of HIV-1 gp120-CD4 receptor complex through targeted interchain disulfide exchange. J Biol Chem. 2010 Aug 13; 285(33):25743-52. PMID: 20538591; PMCID: PMC2919137.
      Citations: 11     Fields:    Translation:HumansCells
    31. Papathanasopoulos MA, Vardas E, Wallis C, Glashoff R, Buttó S, Poli G, Malnati M, Clerici M, Ensoli B. Characterization of HIV type 1 genetic diversity among South African participants enrolled in the AIDS Vaccine Integrated Project (AVIP) study. AIDS Res Hum Retroviruses. 2010 Jun; 26(6):705-9. PMID: 20509797.
      Citations: 6     Fields:    Translation:HumansCells
    32. Fish MQ, Hewer R, Wallis CL, Venter WD, Stevens WS, Papathanasopoulos MA. Natural polymorphisms of integrase among HIV type 1-infected South African patients. AIDS Res Hum Retroviruses. 2010 Apr; 26(4):489-93. PMID: 20377427.
      Citations: 14     Fields:    Translation:HumansCells
    33. Wallis CL, Papathanasopoulos MA, Lakhi S, Karita E, Kamali A, Kaleebu P, Sanders E, Anzala O, Bekker LG, Stevens G, de Wit TF, Stevens W. Affordable in-house antiretroviral drug resistance assay with good performance in non-subtype B HIV-1. J Virol Methods. 2010 Feb; 163(2):505-8. PMID: 19917318; PMCID: PMC2932961.
      Citations: 32     Fields:    Translation:HumansCells
    34. Tzitzivacos DB, Tiemessen CT, Stevens WS, Papathanasopoulos MA. Viral genetic determinants of nonprogressive HIV type 1 subtype C infection in antiretroviral drug-naive children. AIDS Res Hum Retroviruses. 2009 Nov; 25(11):1141-8. PMID: 19895210.
      Citations: 10     Fields:    Translation:HumansCellsPHPublic Health
    35. Tiemessen CT, Shalekoff S, Meddows-Taylor S, Schramm DB, Papathanasopoulos MA, Gray GE, Sherman GG, Coovadia AH, Kuhn L. Cutting Edge: Unusual NK cell responses to HIV-1 peptides are associated with protection against maternal-infant transmission of HIV-1. J Immunol. 2009 May 15; 182(10):5914-8. PMID: 19414742; PMCID: PMC2841685.
      Citations: 38     Fields:    Translation:HumansCellsPHPublic Health
    36. Michler K, Connell BJ, Venter WD, Stevens WS, Capovilla A, Papathanasopoulos MA. Genotypic characterization and comparison of full-length envelope glycoproteins from South African HIV type 1 subtype C primary isolates that utilize CCR5 and/or CXCR4. AIDS Res Hum Retroviruses. 2008 May; 24(5):743-51. PMID: 18507530.
      Citations: 13     Fields:    Translation:HumansCells
    37. Connell BJ, Michler K, Capovilla A, Venter WD, Stevens WS, Papathanasopoulos MA. Emergence of X4 usage among HIV-1 subtype C: evidence for an evolving epidemic in South Africa. AIDS. 2008 Apr 23; 22(7):896-9. PMID: 18427209.
      Citations: 30     Fields:    Translation:HumansCellsPHPublic Health
    38. Coetzer M, Cilliers T, Papathanasopoulos M, Ramjee G, Karim SA, Williamson C, Morris L. Longitudinal analysis of HIV type 1 subtype C envelope sequences from South Africa. AIDS Res Hum Retroviruses. 2007 Feb; 23(2):316-21. PMID: 17331039.
      Citations: 14     Fields:    Translation:HumansCells
    39. Bell CM, Connell BJ, Capovilla A, Venter WD, Stevens WS, Papathanasopoulos MA. Molecular characterization of the HIV type 1 subtype C accessory genes vif, vpr, and vpu. AIDS Res Hum Retroviruses. 2007 Feb; 23(2):322-30. PMID: 17331040.
      Citations: 12     Fields:    Translation:HumansCells
    40. Brandful JA, Coetzer ME, Cilliers T, Phoswa M, Papathanasopoulos MA, Morris L, Moore PL. Phenotypic characterization of HIV type 1 isolates from Ghana. AIDS Res Hum Retroviruses. 2007 Jan; 23(1):144-52. PMID: 17263644.
      Citations: 5     Fields:    Translation:HumansCells
    41. Cilliers T, Willey S, Sullivan WM, Patience T, Pugach P, Coetzer M, Papathanasopoulos M, Moore JP, Trkola A, Clapham P, Morris L. Use of alternate coreceptors on primary cells by two HIV-1 isolates. Virology. 2005 Aug 15; 339(1):136-44. PMID: 15992849.
      Citations: 18     Fields:    Translation:HumansCells
    42. Nkosi SP, Huismans H, Papathanasopoulos MA. Purification and partial characterization of R5, R5X4, and X4 HIV-1 subtype C envelope glycoproteins expressed in insect cells. J Med Virol. 2005 Aug; 76(4):459-63. PMID: 15977243.
      Citations: 1     Fields:    Translation:AnimalsCells
    43. Bessong PO, Larry Obi C, Cilliers T, Choge I, Phoswa M, Pillay C, Papathanasopoulos M, Morris L. Characterization of human immunodeficiency virus type 1 from a previously unexplored region of South Africa with a high HIV prevalence. AIDS Res Hum Retroviruses. 2005 Jan; 21(1):103-9. PMID: 15665650.
      Citations: 7     Fields:    Translation:HumansCells
    44. Cilliers T, Patience T, Pillay C, Papathanasopoulos M, Morris L. Sensitivity of HIV type 1 subtype C isolates to the entry inhibitor T-20. AIDS Res Hum Retroviruses. 2004 May; 20(5):477-82. PMID: 15186521.
      Citations: 9     Fields:    Translation:Cells
    45. Meddows-Taylor S, Papathanasopoulos MA, Kuhn L, Meyers TM, Tiemessen CT. Detection of human immunodeficiency virus type 1 envelope peptide- stimulated T-helper cell responses and variations in the corresponding regions of viral isolates among vertically infected children. Virus Genes. 2004 Apr; 28(3):311-8. PMID: 15266112; PMCID: PMC2364720.
      Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
    46. Papathanasopoulos MA, Patience T, Meyers TM, McCutchan FE, Morris L. Full-length genome characterization of HIV type 1 subtype C isolates from two slow-progressing perinatally infected siblings in South Africa. AIDS Res Hum Retroviruses. 2003 Nov; 19(11):1033-7. PMID: 14686322.
      Citations: 8     Fields:    Translation:HumansCellsPHPublic Health
    47. Hunt GM, Papathanasopoulos MA, Gray GE, Tiemessen CT. Characterisation of near-full length genome sequences of three South African human immunodeficiency virus type 1 subtype C isolates. Virus Genes. 2003 Jan; 26(1):49-56. PMID: 12680693.
      Citations: 1     Fields:    Translation:HumansCells
    48. Papathanasopoulos MA, Hunt GM, Tiemessen CT. Evolution and diversity of HIV-1 in Africa--a review. Virus Genes. 2003; 26(2):151-63. PMID: 12803467.
      Citations: 17     Fields:    Translation:HumansCells
    49. Papathanasopoulos MA, Cilliers T, Morris L, Mokili JL, Dowling W, Birx DL, McCutchan FE. Full-length genome analysis of HIV-1 subtype C utilizing CXCR4 and intersubtype recombinants isolated in South Africa. AIDS Res Hum Retroviruses. 2002 Aug 10; 18(12):879-86. PMID: 12201911.
      Citations: 18     Fields:    Translation:HumansCells
    50. Papathanasopoulos MA, Dykes GA, Revol-Junelles AM, Delfour A, von Holy A, Hastings JW. Sequence and structural relationships of leucocins A-, B- and C-TA33a from Leuconostoc mesenteroides TA33a. Microbiology (Reading). 1998 May; 144 ( Pt 5):1343-1348. PMID: 9611809.
      Citations: 7     Fields:    Translation:Cells
    51. Papathanasopoulos MA, Krier F, Revol-Junelles AM, Lefebvre G, Le Caer JP, von Holy A, Hastings JW. Multiple bacteriocin production by Leuconostoc mesenteroides TA33a and other Leuconostoc/Weissella strains. Curr Microbiol. 1997 Dec; 35(6):331-5. PMID: 9353216.
      Citations: 14     Fields:    Translation:Cells
    52. Felix JV, Papathanasopoulos MA, Smith AA, von Holy A, Hastings JW. Characterization of leucocin B-Ta11a: a bacteriocin from Leuconostoc carnosum Ta11a isolated from meat. Curr Microbiol. 1994 Oct; 29(4):207-12. PMID: 7765496.
      Citations: 14     Fields:    Translation:CellsPHPublic Health
    53. Papathanasopoulos MA, Hastings JW, von Holy A. Antibacterial activity of three Leuconostoc strains isolated from vacuum-packaged processed meats. J Basic Microbiol. 1994; 34(3):173-82. PMID: 8071804.
      Citations: 1     Fields:    Translation:CellsPHPublic Health
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