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Caroline

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Kuhn L, Barnabas S, Cotugno N, Peay H, Goulder P, Cotton M, Violari A, Pahwa S, Reddy K, Tagarro A, Otwombe K, Fry S, Vaz P, Lain MG, Nhampossa T, Archary M, Maiga AI, Puthanakit T, Kityo CM, Foster C, Rojo P, Klein N, Nastouli E, Tiemessen CT, de Rossi A, Ndung'u T, Persaud D, Lichterfeld M, Giaquinto C, Palma P, Rossi P, EPIICAL consortium. Analytical treatment interruption in children living with HIV: position statement from the EPIICAL consortium. Lancet HIV. 2024 Jul 23. PMID: 39059402.
      Citations:    Fields:    
    2. Wiener E, Cottino L, Botha G, Nyangiri O, Noyes H, McLeod A, Jakubosky D, Adebamowo C, Awadalla P, Landour? G, Matshaba M, Matovu E, Ramsay M, Simo G, Simuunza M, Tiemessen C, Wonkam A, Sahibdeen V, Krause A, Lombard Z, Hazelhurst S, as members of the H3Africa Consortium. An assessment of the genomic structural variation landscape in Sub-Saharan African populations. Res Sq. 2024 Jul 08. PMID: 39041024; PMCID: PMC11261963.
      Citations:    
    3. Ka'e AC, Santoro MM, Duca L, Chenwi CA, Ngoufack Jagni Semengue E, Nka AD, Etame NK, Togna Pabo WL, Beloumou G, Mpouel ML, Djupsa S, Takou D, Sosso SM, Tchidjou HK, Colizzi V, Halle-Ekane GE, Perno CF, Lewin S, Jones RB, Tiemessen CT, Ceccherini-Silberstein F, Fokam J. Evaluation of HIV-1 DNA levels among adolescents living with perinatally acquired HIV-1 in Yaounde, Cameroon: A contribution to paediatric HIV cure research in Sub-Saharan Africa. J Virus Erad. 2024 Mar; 10(1):100367. PMID: 38601701; PMCID: PMC11004643.
      Citations:    
    4. Barrios-Tascon A, Strehlau R, Patel F, Burke M, Shiau S, Shen Y, Arpadi SM, Abrams EJ, Tiemessen CT, Kuhn L, LEOPARD study team. Growth Trajectories Over the First Year of Life Among Early-Treated Infants with Human Immunodeficiency Virus and Infants Who are Human Immunodeficiency Virus-Exposed Uninfected. J Pediatr. 2024 Jul; 270:114018. PMID: 38508485; PMCID: PMC11176027.
      Citations:    Fields:    Translation:HumansPHPublic Health
    5. Maenetje P, Baik Y, Schramm DB, Vangu MDW, Wallis RS, Mlotshwa M, Tiemessen CT, Li Y, Kornfeld H, Churchyard G, Auld SC, Bisson GP. Circulating Biomarkers, Fraction of Exhaled Nitric Oxide, and Lung Function in Patients With Human Immunodeficiency Virus and Tuberculosis. J Infect Dis. 2024 Mar 14; 229(3):824-832. PMID: 37386883; PMCID: PMC10938205.
      Citations: 1     Fields:    Translation:HumansCells
    6. Shalekoff S, Dias BDC, Loubser S, Strehlau R, Kuhn L, Tiemessen CT. Higher CCR5 density on CD4 + T-cells in mothers and infants is associated with increased risk of in-utero HIV-1 transmission. AIDS. 2024 06 01; 38(7):945-954. PMID: 38329228; PMCID: PMC11064911.
      Citations:    Fields:    Translation:HumansCellsPHPublic Health
    7. Ka'e AC, Santoro MM, Nanfack A, Ngoufack Jagni Semengue E, Yagai B, Nka AD, Ambada G, Mpouel ML, Sagnia B, Kenou L, Sanhanfo M, Togna Pabo WLR, Takou D, Chenwi CA, Sonela N, Sosso SM, Nkenfou C, Colizzi V, Halle-Ekane GE, Ndjolo A, Ceccherini-Silberstein F, Perno CF, Lewin S, Tiemessen CT, Fokam J. Characterization of HIV-1 Reservoirs in Children and Adolescents: A?Systematic Review and Meta-Analysis Toward Pediatric HIV Cure. J Pediatr. 2024 Apr; 267:113919. PMID: 38237889.
      Citations:    Fields:    Translation:HumansCells
    8. Twesigomwe D, Dr?gem?ller BI, Wright GEB, Adebamowo C, Agongo G, Boua PR, Matshaba M, Paximadis M, Ramsay M, Simo G, Simuunza MC, Tiemessen CT, Lombard Z, Hazelhurst S. Characterization of CYP2B6 and CYP2A6 Pharmacogenetic Variation in Sub-Saharan African Populations. Clin Pharmacol Ther. 2024 03; 115(3):576-594. PMID: 38049200.
      Citations: 1     Fields:    Translation:Humans
    9. Ka'e AC, Nanfack A, Santoro MM, Yagai B, Ambada G, Sagnia B, Nka AD, Ngoufack Jagni Semengue E, Pabo W, Takou D, Sonela N, Colizzi V, Perno CF, Ceccherini-Silberstein F, Lewin SR, Tiemessen CT, Fokam J. Characterisation of HIV-1 reservoirs in paediatric populations: protocol for a systematic review and meta-analysis. BMJ Open. 2023 10 10; 13(10):e073672. PMID: 37816567; PMCID: PMC10565271.
      Citations: 1     Fields:    Translation:HumansCells
    10. Ka'e AC, Nanfack AJ, Ambada G, Santoro MM, Takou D, Semengue ENJ, Nka AD, Bala MLM, Endougou ON, Elong E, Beloumou G, Djupsa S, Gouissi DH, Fainguem N, Tchouaket MCT, Sosso SM, Kesseng D, Ndongo FA, Sonela N, Kamta ACL, Tchidjou HK, Ndomgue T, Ndiang STM, Nlend AEN, Nkenfou CN, Montesano C, Halle-Ekane GE, Cappelli G, Tiemessen CT, Colizzi V, Ceccherini-Silberstein F, Perno CF, Fokam J. Inflammatory profile of vertically HIV-1 infected adolescents receiving ART in Cameroon: a contribution toward optimal pediatric HIV control strategies. Front Immunol. 2023; 14:1239877. PMID: 37646023; PMCID: PMC10461471.
      Citations: 1     Fields:    Translation:HumansCells
    11. Kuhn L, Wang T, Li F, Strehlau R, Tobin NH, Violari A, Brooker S, Patel F, Liberty A, Shiau S, Arpadi SM, Wadhwa S, Yin MT, Wang S, Tiemessen CT, Aldrovandi GM. Microbiota in the oral cavity of school-age children with HIV who started antiretroviral therapy at young ages in South Africa. AIDS. 2023 08 01; 37(10):1583-1591. PMID: 37199568; PMCID: PMC10524539.
      Citations:    Fields:    Translation:Humans
    12. Yoon H, Wake RM, Nakouzi AS, Wang T, Agalliu I, Tiemessen CT, Govender NP, Jarvis JN, Harrison TS, Pirofski LA. Association of Antibody Immunity With Cryptococcal Antigenemia and Mortality in a South African Cohort With Advanced Human Immunodeficiency Virus Disease. Clin Infect Dis. 2023 02 18; 76(4):649-657. PMID: 35915964; PMCID: PMC10226730.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    13. Baik Y, Maenetje P, Schramm D, Tiemessen C, Ncube I, Churchyard G, Wallis R, Vangu MD, Kornfeld H, Li Y, Auld SC, Bisson GP. Lung function and collagen 1a levels are associated with changes in 6?min walk test distance during treatment of TB among HIV-infected adults: a prospective cohort study. BMC Pulm Med. 2023 Feb 03; 23(1):53. PMID: 36737697; PMCID: PMC9896708.
      Citations:    Fields:    Translation:Humans
    14. Twesigomwe D, Dr?gem?ller BI, Wright GEB, Adebamowo C, Agongo G, Boua PR, Matshaba M, Paximadis M, Ramsay M, Simo G, Simuunza MC, Tiemessen CT, Lombard Z, Hazelhurst S. Characterization of CYP2D6 Pharmacogenetic Variation in Sub-Saharan African Populations. Clin Pharmacol Ther. 2023 03; 113(3):643-659. PMID: 36111505; PMCID: PMC9957841.
      Citations: 5     Fields:    Translation:Humans
    15. May AK, Seymour H, Etheredge H, Maher H, Nunes MC, Madhi SA, Sokhela SM, Venter WDF, Martinson N, Nabeemeeah F, Cohen C, Moyes J, Walaza S, Tempia S, Kleynhans J, von Gottberg A, Nel J, Dawood H, Variava E, Tollman S, Kahn K, Herbst K, Wong EB, Tiemessen CT, van Blydenstein A, Murray L, Venter M, Fabian J, Ramsay M. Coronavirus Host Genomics Study: South Africa (COVIGen-SA). Glob Health Epidemiol Genom. 2022; 2022:7405349. PMID: 36263375; PMCID: PMC9560830.
      Citations:    Fields:    Translation:HumansCells
    16. Ebonwu J, Lassauni?re R, Paximadis M, Strehlau R, Gray GE, Kuhn L, Tiemessen CT. FCGR3A gene duplication, Fc?RIIb-232TT and Fc?RIIIb-HNA1a associate with an increased risk of vertical acquisition of HIV-1. PLoS One. 2022; 17(9):e0273933. PMID: 36084039; PMCID: PMC9462732.
      Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
    17. Morris SE, Strehlau R, Shiau S, Abrams EJ, Tiemessen CT, Kuhn L, Yates AJ, EPIICAL Consortium and the LEOPARD study team. Healthy dynamics of CD4 T cells may drive HIV resurgence in perinatally-infected infants on antiretroviral therapy. PLoS Pathog. 2022 08; 18(8):e1010751. PMID: 35969641; PMCID: PMC9410541.
      Citations:    Fields:    Translation:HumansCells
    18. Lassauni?re R, Tiemessen CT. SARS-CoV-2 vaccine-induced antibody levels: what lies beneath. Lancet Rheumatol. 2022 Sep; 4(9):e579-e581. PMID: 35966646; PMCID: PMC9363038.
      Citations:    Fields:    
    19. Nkone P, Loubser S, Quinn TC, Redd AD, Laeyendecker O, Tiemessen CT, Mayaphi SH. Evaluation of the HIV-1 Polymerase Gene Sequence Diversity for Prediction of Recent HIV-1 Infections Using Shannon Entropy Analysis. Viruses. 2022 07 21; 14(7). PMID: 35891568; PMCID: PMC9324365.
      Citations: 2     Fields:    Translation:HumansCells
    20. Nkone P, Loubser S, Quinn TC, Redd AD, Ismail A, Tiemessen CT, Mayaphi SH. Correction to: Deep sequencing of the HIV-1 polymerase gene for characterisation of cytotoxic T-lymphocyte epitopes during early and chronic disease stages. Virol J. 2022 May 05; 19(1):78. PMID: 35513827; PMCID: PMC9069713.
      Citations:    Fields:    
    21. Wake RM, Ismail NA, Omar SV, Ismail F, Tiemessen CT, Harrison TS, Jarvis JN, Govender NP. Prior Pulmonary Tuberculosis Is a Risk Factor for Asymptomatic Cryptococcal Antigenemia in a Cohort of Adults With Advanced Human Immunodeficiency Virus Disease. Open Forum Infect Dis. 2022 Jul; 9(7):ofac202. PMID: 35794929; PMCID: PMC9251663.
      Citations: 1     
    22. Nkone P, Loubser S, Quinn TC, Redd AD, Ismail A, Tiemessen CT, Mayaphi SH. Deep sequencing of the HIV-1 polymerase gene for characterisation of cytotoxic T-lymphocyte epitopes during early and chronic disease stages. Virol J. 2022 03 28; 19(1):56. PMID: 35346259; PMCID: PMC8959563.
      Citations: 2     Fields:    Translation:HumansCells
    23. Suchard MS, Martinson N, Malfeld S, de Assis Rosa D, Mackelprang RD, Lingappa J, Hou X, Rees H, Delany-Moretlwe S, Goldfein H, Ranchod H, Coetzee D, Otwombe K, Morris L, Tiemessen CT, Savulescu DM. Alloimmunity to Class 2 Human Leucocyte Antigens May Reduce HIV-1 Acquisition - A Nested Case-Control Study in HIV-1 Serodiscordant Couples. Front Immunol. 2022; 13:813412. PMID: 35401581; PMCID: PMC8987441.
      Citations:    Fields:    Translation:HumansCells
    24. Kuhn L, Paximadis M, Da Costa Dias B, Shen Y, Mncube S, Strehlau R, Shiau S, Patel F, Burke M, Technau KG, Sherman G, Loubser S, Abrams EJ, Tiemessen CT. Predictors of Cell-Associated Human Immunodeficiency Virus (HIV)-1 DNA Over 1 Year in Very Early Treated Infants. Clin Infect Dis. 2022 03 23; 74(6):1047-1054. PMID: 34185838; PMCID: PMC8946667.
      Citations: 4     Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
    25. Wake RM, Govender NP, Omar SV, Ismail F, Tiemessen CT, Harrison TS, Jarvis JN. Rapid urine-based screening tests increase the yield of same-day tuberculosis diagnoses among patients living with advanced HIV disease. AIDS. 2022 May 01; 36(6):839-844. PMID: 35075041.
      Citations:    Fields:    Translation:HumansCells
    26. Picton ACP, Paximadis M, Koor GW, Bharuthram A, Shalekoff S, Lassauniere R, Ive P, Tiemessen CT. Reduced CCR5 Expression and Immune Quiescence in Black South African HIV-1 Controllers. Front Immunol. 2021; 12:781263. PMID: 34987508; PMCID: PMC8720782.
      Citations: 1     Fields:    Translation:HumansCells
    27. Lassaunière R, Tiemessen CT. Fc?R Genetic Variation and HIV-1 Vaccine Efficacy: Context And Considerations. Front Immunol. 2021; 12:788203. PMID: 34975881; PMCID: PMC8714752.
      Citations: 3     Fields:    Translation:HumansCells
    28. Ebonwu J, Lassaunière R, Paximadis M, Goosen M, Strehlau R, Gray GE, Kuhn L, Tiemessen CT. An HIV Vaccine Protective Allele in FCGR2C Associates With Increased Odds of Perinatal HIV Acquisition. Front Immunol. 2021; 12:760571. PMID: 34917081; PMCID: PMC8668943.
      Citations: 2     Fields:    Translation:HumansCellsPHPublic Health
    29. Mukendi A, Kufa T, Murray T, Burke M, Strehlau R, Technau KG, Tiemessen CT, Sherman GG, Mazanderani AH. Evaluating the performance of the GeneXpert HIV-1 qualitative assay as a consecutive test for a new early infant diagnosis algorithm in South Africa. S Afr Med J. 2021 09 02; 111(9):857-861. PMID: 34949250.
      Citations:    Fields:    Translation:HumansCellsPHPublic Health
    30. Govender Y, Shalekoff S, Ebrahim O, Waja Z, Chaisson RE, Martinson N, Tiemessen CT. Systemic DPP4/CD26 is associated with natural HIV-1 control: Implications for COVID-19 susceptibility. Clin Immunol. 2021 09; 230:108824. PMID: 34391936; PMCID: PMC8360992.
      Citations: 3     Fields:    Translation:HumansCells
    31. da Rocha JEB, Othman H, Tiemessen CT, Botha G, Ramsay M, Masimirembwa C, Adebamowo C, Choudhury A, Brandenburg JT, Matshaba M, Simo G, Gamo FJ, Hazelhurst S, as members of the H3Africa Consortium. G6PD distribution in sub-Saharan Africa and potential risks of using chloroquine/hydroxychloroquine based treatments for COVID-19. Pharmacogenomics J. 2021 12; 21(6):649-656. PMID: 34302047; PMCID: PMC8299738.
      Citations: 8     Fields:    Translation:Humans
    32. Mukendi A, Kufa T, Sherman GG, Technau KG, Tiemessen CT, Mazanderani AH. Evaluation of the Aptima HIV-1 Quant Dx assay for HIV diagnosis at birth in South Africa. Diagn Microbiol Infect Dis. 2021 Nov; 101(3):115467. PMID: 34391073.
      Citations:    Fields:    Translation:HumansCellsPHPublic Health
    33. Shiau S, Strehlau R, Shen Y, He Y, Patel F, Burke M, Abrams EJ, Tiemessen CT, Wang S, Kuhn L. Virologic Response to Very Early HIV Treatment in Neonates. J Clin Med. 2021 May 12; 10(10). PMID: 34066021; PMCID: PMC8151270.
      Citations: 2     
    34. Shalekoff S, Loubser S, Dias BDC, Strehlau R, Shiau S, Wang S, He Y, Abrams EJ, Kuhn L, Tiemessen CT. Normalization of B Cell Subsets but Not T Follicular Helper Phenotypes in Infants With Very Early Antiretroviral Treatment. Front Pediatr. 2021; 9:618191. PMID: 33996678; PMCID: PMC8118125.
      Citations: 2     
    35. da Rocha JEB, Othman H, Botha G, Cottino L, Twesigomwe D, Ahmed S, Drögemöller BI, Fadlelmola FM, Machanick P, Mbiyavanga M, Panji S, Wright GEB, Adebamowo C, Matshaba M, Ramsay M, Simo G, Simuunza MC, Tiemessen CT, Baldwin S, Chiano M, Cox C, Gross AS, Thomas P, Gamo FJ, Hazelhurst S. The Extent and Impact of Variation in ADME Genes in Sub-Saharan African Populations. Front Pharmacol. 2021; 12:634016. PMID: 34721006; PMCID: PMC8549571.
      Citations: 14     
    36. Loubser S, Da Costa Dias B, Shalekoff S, Gentle NL, Tiemessen CT. Lack of association of KIR2DL1-R245 and KIR2DL1-C245 with HIV-1 control in black South Africans with HLA-C2. Hum Immunol. 2021 Aug; 82(8):600-607. PMID: 33906789.
      Citations:    Fields:    Translation:HumansCells
    37. Tiemessen CT. The many faces of HIV elite control. EBioMedicine. 2021 04; 66:103305. PMID: 33813135; PMCID: PMC8053809.
      Citations: 2     Fields:    Translation:HumansCells
    38. Paximadis M, Picton ACP, Sengupta D, Ramsay M, Puren A, Tiemessen CT. Interleukin-8 genetic diversity, haplotype structure and production differ in two ethnically distinct South African populations. Cytokine. 2021 07; 143:155489. PMID: 33814271.
      Citations:    Translation:HumansCells
    39. Glanzmann B, Jooste T, Ghoor S, Gordon R, Mia R, Mao J, Li H, Charls P, Douman C, Kotze MJ, Peeters AV, Loots G, Esser M, Tiemessen CT, Wilkinson RJ, Louw J, Gray G, Warren RM, Möller M, Kinnear C. Human whole genome sequencing in South Africa. Sci Rep. 2021 01 12; 11(1):606. PMID: 33436733; PMCID: PMC7803990.
      Citations: 8     Fields:    Translation:Humans
    40. Patel F, Shiau S, Strehlau R, Shen Y, Burke M, Paximadis M, Shalekoff S, Schramm D, Technau KG, Sherman GG, Coovadia A, Tiemessen CT, Abrams EJ, Kuhn L. Low Pretreatment Viral Loads in Infants With HIV in an Era of High-maternal Antiretroviral Therapy Coverage. Pediatr Infect Dis J. 2021 01; 40(1):55-59. PMID: 32925542; PMCID: PMC7722046.
      Citations: 1     Fields:    Translation:HumansPHPublic Health
    41. Seedat F, James I, Loubser S, Waja Z, Mallal SA, Hoffmann C, Tiemessen CT, Chaisson RE, Martinson NA. Human leukocyte antigen associations with protection against tuberculosis infection and disease in human immunodeficiency virus-1 infected individuals, despite household tuberculosis exposure and immune suppression. Tuberculosis (Edinb). 2021 01; 126:102023. PMID: 33249336.
      Citations: 6     Fields:    Translation:HumansCells
    42. Kannambath S, Jarvis JN, Wake RM, Longley N, Loyse A, Matzaraki V, Aguirre-Gamboa R, Wijmenga C, Doyle R, Paximadis M, Tiemessen CT, Kumar V, Pittman A, Meintjes G, Harrison TS, Netea MG, Bicanic T. Genome-Wide Association Study Identifies Novel Colony Stimulating Factor 1 Locus Conferring Susceptibility to Cryptococcosis in Human Immunodeficiency Virus-Infected South Africans. Open Forum Infect Dis. 2020 Nov; 7(11):ofaa489. PMID: 33269293; PMCID: PMC7686661.
      Citations: 9     
    43. Nel JS, Conradie F, Botha J, Etheredge H, Fabian J, Levin L, Mazanderani AH, Moorhouse M, Muller E, Tiemessen C, Thomson D, Turner J. Southern African HIV Clinicians Society guidelines for solid organ transplantation in human immunodeficiency virus: An evidence-based framework for human immunodeficiency virus-positive donors and recipients. South Afr J HIV Med. 2020; 21(1):1133. PMID: 33240537; PMCID: PMC7670031.
      Citations: 2     
    44. Morris SE, Dziobek-Garrett L, Strehlau R, Schröter J, Shiau S, Anelone AJN, Paximadis M, de Boer RJ, Abrams EJ, Tiemessen CT, Kuhn L, Yates AJ, EPIICAL Consortium and the LEOPARD study team. Quantifying the Dynamics of HIV Decline in Perinatally Infected Neonates on Antiretroviral Therapy. J Acquir Immune Defic Syndr. 2020 10 01; 85(2):209-218. PMID: 32576731; PMCID: PMC8818299.
      Citations: 3     Fields:    Translation:HumansCellsPHPublic Health
    45. Ravimohan S, Maenetje P, Auld SC, Ncube I, Mlotshwa M, Chase W, Tiemessen CT, Vangu MD, Wallis RS, Churchyard G, Weissman D, Kornfeld H, Bisson GP. A Common NLRC4 Gene Variant Associates With Inflammation and Pulmonary Function in Human Immunodeficiency Virus and Tuberculosis. Clin Infect Dis. 2020 08 14; 71(4):924-932. PMID: 31751447; PMCID: PMC7428399.
      Citations: 10     Fields:    Translation:HumansCells
    46. da Rocha J, Othman H, Tiemessen CT, Botha G, Ramsay M, Masimirembwa C, Adebamowo C, Choudhury A, Brandenburg JT, Matshaba M, Simo G, Gamo FJ, Hazelhurst S. G6PD variant distribution in sub-Saharan Africa and potential risks of using chloroquine/hydroxychloroquine based treatments for COVID-19. medRxiv. 2020 Jun 02. PMID: 32577690; PMCID: PMC7302299.
      Citations:    
    47. Wake RM, Govender NP, Omar T, Nel C, Mazanderani AH, Karat AS, Ismail NA, Tiemessen CT, Jarvis JN, Harrison TS. Cryptococcal-related Mortality Despite Fluconazole Preemptive Treatment in a Cryptococcal Antigen Screen-and-Treat Program. Clin Infect Dis. 2020 04 10; 70(8):1683-1690. PMID: 31179488; PMCID: PMC7346756.
      Citations: 25     Fields:    Translation:HumansAnimals
    48. Strehlau R, Paximadis M, Sherman GG, Abrams EJ, Tiemessen CT, Kuhn L. Response to Zhao and Zhou: Diagnosis of HIV infection in breastfed infants of mothers on antiretroviral therapy. AIDS. 2020 04 01; 34(5):798-799. PMID: 32167995; PMCID: PMC7111299.
      Citations:    Fields:    Translation:HumansPHPublic Health
    49. Dias BDC, Paximadis M, Martinson N, Chaisson RE, Ebrahim O, Tiemessen CT. The impact of bone marrow stromal antigen-2 (BST2) gene variants on HIV-1 control in black South African individuals. Infect Genet Evol. 2020 06; 80:104216. PMID: 32006707; PMCID: PMC8752124.
      Citations: 2     Fields:    Translation:HumansCells
    50. Kuhn L, Strehlau R, Shiau S, Patel F, Shen Y, Technau KG, Burke M, Sherman G, Coovadia A, Aldrovandi GM, Hazra R, Tsai WY, Tiemessen CT, Abrams EJ, LEOPARD Study Team. Early antiretroviral treatment of infants to attain HIV remission. EClinicalMedicine. 2020 Jan; 18:100241. PMID: 31993578; PMCID: PMC6978195.
      Citations: 25     
    51. Loubser S, Paximadis M, Gentle NL, Puren A, Tiemessen CT. Human leukocyte antigen class I (A, B, C) and class II (DPB1, DQB1, DRB1) allele and haplotype variation in Black South African individuals. Hum Immunol. 2020 Jan; 81(1):6-7. PMID: 31843212.
      Citations: 3     Fields:    Translation:Humans
    52. Botha J, Fabian J, Etheredge H, Conradie F, Tiemessen CT. HIV and Solid Organ Transplantation: Where Are we Now. Curr HIV/AIDS Rep. 2019 10; 16(5):404-413. PMID: 31482298; PMCID: PMC6813753.
      Citations: 11     Fields:    Translation:Humans
    53. Mzingwane ML, Hunt G, Lassauniere R, Kalimashe M, Bongwe A, Ledwaba J, Chaisson RE, Martinson N, Richter K, Bowyer SM, Tiemessen CT. Detection and molecular characterization of urinary tract HIV-1 populations. Ann Clin Microbiol Antimicrob. 2019 Sep 24; 18(1):27. PMID: 31551072; PMCID: PMC6760049.
      Citations: 1     Fields:    Translation:HumansCells
    54. Loubser S, Kwenda S, Sengupta D, Tiemessen CT. Identification of a novel allele, HLA-DPB1*34:01:01:03, in Black South African individuals. HLA. 2019 12; 94(6):547-549. PMID: 31464043.
      Citations:    Fields:    Translation:HumansCells
    55. Loubser S, Kwenda S, Sengupta D, Tiemessen CT. Identification of a novel recombinant allele, HLA-DPB1*835:01:01:02, in Black South African individuals. HLA. 2019 12; 94(6):549-551. PMID: 31478356.
      Citations:    Fields:    Translation:HumansCells
    56. Strehlau R, Paximadis M, Patel F, Burke M, Technau KG, Shiau S, Abrams EJ, Sherman GG, Hunt G, Ledwaba J, Mazanderani AH, Tiemessen CT, Kuhn L, LEOPARD Study Team. HIV diagnostic challenges in breast-fed infants of mothers on antiretroviral therapy. AIDS. 2019 09 01; 33(11):1751-1756. PMID: 31149944; PMCID: PMC6663570.
      Citations: 6     Fields:    Translation:HumansPHPublic Health
    57. Jaumdally SZ, Liebenberg LJP, Gumbi PP, Little F, Jaspan HB, Gamieldien H, Tiemessen CT, Coetzee D, Martin DP, Williamson C, Williamson AL, Passmore JS. Partner HIV Serostatus Impacts Viral Load, Genital HIV Shedding, and Immune Activation in HIV-Infected Individuals. J Acquir Immune Defic Syndr. 2019 09 01; 82(1):51-60. PMID: 31169767.
      Citations: 1     Fields:    Translation:Humans
    58. Koor GW, Paximadis M, Picton ACP, Karatas F, Loubser SA, He W, Ahuja SK, Chaisson RE, Martinson N, Ebrahim O, Tiemessen CT. Cis-regulatory genetic variants in the CCR5 gene and natural HIV-1 control in black South Africans. Clin Immunol. 2019 08; 205:16-24. PMID: 31100442; PMCID: PMC6646080.
      Citations: 5     Fields:    Translation:HumansCells
    59. Etheredge HR, Fabian J, Duncan M, Conradie F, Tiemessen C, Botha J. Needs must: living donor liver transplantation from an HIV-positive mother to her HIV-negative child in Johannesburg, South Africa. J Med Ethics. 2019 05; 45(5):287-290. PMID: 31085631; PMCID: PMC6582740.
      Citations: 3     Fields:    Translation:Humans
    60. Phaahla NG, Lassaunière R, Da Costa Dias B, Waja Z, Martinson NA, Tiemessen CT. Chronic HIV-1 Infection Alters the Cellular Distribution of Fc?RIIIa and the Functional Consequence of the Fc?RIIIa-F158V Variant. Front Immunol. 2019; 10:735. PMID: 31024562; PMCID: PMC6467939.
      Citations: 2     Fields:    Translation:HumansCells
    61. Julg B, Dee L, Ananworanich J, Barouch DH, Bar K, Caskey M, Colby DJ, Dawson L, Dong KL, Dubé K, Eron J, Frater J, Gandhi RT, Geleziunas R, Goulder P, Hanna GJ, Jefferys R, Johnston R, Kuritzkes D, Li JZ, Likhitwonnawut U, van Lunzen J, Martinez-Picado J, Miller V, Montaner LJ, Nixon DF, Palm D, Pantaleo G, Peay H, Persaud D, Salzwedel J, Salzwedel K, Schacker T, Sheikh V, Søgaard OS, Spudich S, Stephenson K, Sugarman J, Taylor J, Tebas P, Tiemessen CT, Tressler R, Weiss CD, Zheng L, Robb ML, Michael NL, Mellors JW, Deeks SG, Walker BD. Recommendations for analytical antiretroviral treatment interruptions in HIV research trials-report of a consensus meeting. Lancet HIV. 2019 04; 6(4):e259-e268. PMID: 30885693; PMCID: PMC6688772.
      Citations: 102     Fields:    Translation:Humans
    62. Violari A, Cotton MF, Kuhn L, Schramm DB, Paximadis M, Loubser S, Shalekoff S, Da Costa Dias B, Otwombe K, Liberty A, McIntyre J, Babiker A, Gibb D, Tiemessen CT. A child with perinatal HIV infection and long-term sustained virological control following antiretroviral treatment cessation. Nat Commun. 2019 01 24; 10(1):412. PMID: 30679439; PMCID: PMC6345921.
      Citations: 48     Fields:    Translation:HumansCells
    63. Lassaunière R, Paximadis M, Ebrahim O, Chaisson RE, Martinson NA, Tiemessen CT. The FCGR2C allele that modulated the risk of HIV-1 infection in the Thai RV144 vaccine trial is implicated in HIV-1 disease progression. Genes Immun. 2019 11; 20(8):651-659. PMID: 30563969; PMCID: PMC6881233.
      Citations: 7     Fields:    Translation:Humans
    64. Botha J, Conradie F, Etheredge H, Fabian J, Duncan M, Haeri Mazanderani A, Paximadis M, Maher H, Britz R, Loveland J, Ströbele B, Rambarran S, Mahomed A, Terblanche A, Beretta M, Brannigan L, Pienaar M, Archibald-Durham L, Lang A, Tiemessen CT. Living donor liver transplant from an HIV-positive mother to her HIV-negative child: opening up new therapeutic options. AIDS. 2018 10 23; 32(16):F13-F19. PMID: 30281558; PMCID: PMC6200383.
      Citations: 9     Fields:    Translation:HumansCells
    65. Harris L, van Zyl LJ, Kirby-McCullough BM, Damelin LH, Tiemessen CT, Trindade M. Identification and sequence analysis of two novel cryptic plasmids isolated from the vaginal mucosa of South African women. Plasmid. 2018 06; 98:56-62. PMID: 30240699.
      Citations: 1     Fields:    Translation:HumansCells
    66. Kuhn L, Paximadis M, Da Costa Dias B, Loubser S, Strehlau R, Patel F, Shiau S, Coovadia A, Abrams EJ, Tiemessen CT. Age at antiretroviral therapy initiation and cell-associated HIV-1 DNA levels in HIV-1-infected children. PLoS One. 2018; 13(4):e0195514. PMID: 29649264; PMCID: PMC5896970.
      Citations: 33     Fields:    Translation:HumansCells
    67. Ravimohan S, Nfanyana K, Tamuhla N, Tiemessen CT, Weissman D, Bisson GP. Common Variation in NLRP3 Is Associated With Early Death and Elevated Inflammasome Biomarkers Among Advanced HIV/TB Co-infected Patients in Botswana. Open Forum Infect Dis. 2018 May; 5(5):ofy075. PMID: 29732382; PMCID: PMC5928406.
      Citations: 11     
    68. Technau KG, Mazanderani AH, Kuhn L, Hans L, Strehlau R, Abrams EJ, Conradie M, Coovadia A, Mbete N, Murnane PM, Patel F, Shiau S, Tiemessen CT, Sherman GG. Prevalence and outcomes of HIV-1 diagnostic challenges during universal birth testing - an urban South African observational cohort. J Int AIDS Soc. 2017 08 29; 20(Suppl 6):21761. PMID: 28872276; PMCID: PMC6192462.
      Citations: 13     Fields:    Translation:HumansCellsPHPublic Health
    69. Gentle NL, Loubser S, Paximadis M, Puren A, Tiemessen CT. Killer-cell immunoglobulin-like receptor (KIR) and human leukocyte antigen (HLA) class I genetic diversity in four South African populations. Hum Immunol. 2017 Jul - Aug; 78(7-8):503-509. PMID: 28571758.
      Citations: 6     Fields:    Translation:HumansCells
    70. Jaumdally SZ, Picton A, Tiemessen CT, Paximadis M, Jaspan HB, Gamieldien H, Masson L, Coetzee D, Williamson AL, Little F, Gumbi PP, Passmore JS. CCR5 expression, haplotype and immune activation in protection from infection in HIV-exposed uninfected individuals in HIV-serodiscordant relationships. Immunology. 2017 08; 151(4):464-473. PMID: 28398593; PMCID: PMC5506425.
      Citations: 8     Fields:    Translation:HumansCellsPHPublic Health
    71. Loubser S, Paximadis M, Tiemessen CT. Human leukocyte antigen class I (A, B and C) allele and haplotype variation in a South African Indian population. Hum Immunol. 2017 Jul - Aug; 78(7-8):468-470. PMID: 28465172.
      Citations: 1     Fields:    Translation:Humans
    72. Loubser S, Paximadis M, Tiemessen CT. Human leukocyte antigen class I (A, B and C) allele and haplotype variation in a South African Mixed ancestry population. Hum Immunol. 2017 May - Jun; 78(5-6):399-400. PMID: 28438553; PMCID: PMC5451074.
      Citations: 1     Fields:    Translation:HumansCells
    73. Picton ACP, Paximadis M, Chaisson RE, Martinson NA, Tiemessen CT. CXCR6 gene characterization in two ethnically distinct South African populations and association with viraemic disease control in HIV-1-infected black South African individuals. Clin Immunol. 2017 07; 180:69-79. PMID: 28428094; PMCID: PMC5505515.
      Citations: 9     Fields:    Translation:HumansCells
    74. Mzingwane ML, Tiemessen CT. Mechanisms of HIV persistence in HIV reservoirs. Rev Med Virol. 2017 03; 27(2). PMID: 28128885.
      Citations: 27     Fields:    Translation:HumansCells
    75. Paximadis M, Ngqobe RN, Chaisson RE, Martinson NA, Tiemessen CT. RICH2 is implicated in viraemic control of HIV-1 in black South African individuals. Infect Genet Evol. 2017 04; 49:78-87. PMID: 28069446; PMCID: PMC5330811.
      Citations: 2     Fields:    Translation:HumansCells
    76. Mzingwane ML, Tiemessen CT, Richter KL, Mayaphi SH, Hunt G, Bowyer SM. Pre-treatment minority HIV-1 drug resistance mutations and long term virological outcomes: is prediction possible? Virol J. 2016 10 12; 13(1):170. PMID: 27733203; PMCID: PMC5062819.
      Citations: 6     Fields:    Translation:HumansCells
    77. Lassaunière R, Musekiwa A, Gray GE, Kuhn L, Tiemessen CT. Perinatal HIV-1 transmission: Fc gamma receptor variability associates with maternal infectiousness and infant susceptibility. Retrovirology. 2016 06 10; 13(1):40. PMID: 27287460; PMCID: PMC4902924.
      Citations: 10     Fields:    Translation:HumansCellsPHPublic Health
    78. Lassaunière R, Tiemessen CT. Variability at the FCGR locus: characterization in Black South Africans and evidence for ethnic variation in and out of Africa. Genes Immun. 2016 Mar; 17(2):93-104. PMID: 26673965.
      Citations: 23     Fields:    Translation:HumansCells
    79. Jansen van Vuren P, Shalekoff S, Grobbelaar AA, Archer BN, Thomas J, Tiemessen CT, Paweska JT. Serum levels of inflammatory cytokines in Rift Valley fever patients are indicative of severe disease. Virol J. 2015 Oct 06; 12:159. PMID: 26437779; PMCID: PMC4595326.
      Citations: 25     Fields:    Translation:HumansCellsPHPublic Health
    80. Gornalusse GG, Mummidi S, Gaitan AA, Jimenez F, Ramsuran V, Picton A, Rogers K, Manoharan MS, Avadhanam N, Murthy KK, Martinez H, Molano Murillo A, Chykarenko ZA, Hutt R, Daskalakis D, Shostakovich-Koretskaya L, Abdool Karim S, Martin JN, Deeks SG, Hecht F, Sinclair E, Clark RA, Okulicz J, Valentine FT, Martinson N, Tiemessen CT, Ndung'u T, Hunt PW, He W, Ahuja SK. Epigenetic mechanisms, T-cell activation, and CCR5 genetics interact to regulate T-cell expression of CCR5, the major HIV-1 coreceptor. Proc Natl Acad Sci U S A. 2015 Aug 25; 112(34):E4762-71. PMID: 26307764; PMCID: PMC4553789.
      Citations: 31     Fields:    Translation:HumansCells
    81. Damelin LH, Fernandes MA, Tiemessen CT. Alginate microbead-encapsulated silver complexes for selective delivery of broad-spectrum silver-based microbicides. Int J Antimicrob Agents. 2015 Oct; 46(4):394-400. PMID: 26184337.
      Citations: 4     Fields:    Translation:HumansCellsPHPublic Health
    82. Kuhn L, Schramm DB, Shiau S, Strehlau R, Pinillos F, Technau K, Coovadia A, Abrams EJ, Puren A, Tiemessen CT. Young age at start of antiretroviral therapy and negative HIV antibody results in HIV-infected children when suppressed. AIDS. 2015 Jun 01; 29(9):1053-60. PMID: 25870988; PMCID: PMC4538987.
      Citations: 23     Fields:    Translation:Humans
    83. Hong HA, Paximadis M, Gray GE, Kuhn L, Tiemessen CT. Maternal human leukocyte antigen-G (HLA-G) genetic variants associate with in utero mother-to-child transmission of HIV-1 in Black South Africans. Infect Genet Evol. 2015 Mar; 30:147-158. PMID: 25541520; PMCID: PMC4333678.
      Citations: 6     Fields:    Translation:HumansCellsPHPublic Health
    84. Loubser S, Paximadis M, Gentle N, Puren A, Gray CM, Tiemessen CT. Frequencies of immune hypersensitivity reaction-associated HLA class I alleles in healthy South African Indian and mixed ancestry populations determined by a novel real-time PCR assay. Tissue Antigens. 2014 Oct; 84(4):389-97. PMID: 25154892.
      Citations: 1     Fields:    Translation:Humans
    85. Bharuthram A, Paximadis M, Picton AC, Tiemessen CT. Comparison of a quantitative Real-Time PCR assay and droplet digital PCR for copy number analysis of the CCL4L genes. Infect Genet Evol. 2014 Jul; 25:28-35. PMID: 24727646.
      Citations: 19     Fields:    Translation:Humans
    86. McLeod KE, Omar T, Tiemessen CT, Tshabangu N, Martinson NA. Prevalence of premalignant cervical lesions in women with a long-term nonprogressor or HIV controller phenotype. J Acquir Immune Defic Syndr. 2014 Jan 01; 65(1):e29-32. PMID: 24419070; PMCID: PMC3987062.
      Citations: 2     Fields:    Translation:Humans
    87. Hong HA, Paximadis M, Gray GE, Kuhn L, Tiemessen CT. KIR2DS4 allelic variants: Differential effects on in utero and intrapartum HIV-1 mother-to-child transmission. Clin Immunol. 2013 Dec; 149(3):498-508. PMID: 24239756.
      Citations: 10     Fields:    Translation:HumansCellsPHPublic Health
    88. Gentle NL, Paximadis M, Puren A, Tiemessen CT. Genetic variability in markers of HLA-C expression in two diverse South African populations. PLoS One. 2013; 8(7):e67780. PMID: 23861805; PMCID: PMC3702582.
      Citations: 7     Fields:    Translation:HumansPHPublic Health
    89. Shalekoff S, Schramm DB, Lassaunière R, Picton AC, Tiemessen CT. Differences are evident within the CXCR4-CXCL12 axis between ethnically divergent South African populations. Cytokine. 2013 Mar; 61(3):792-800. PMID: 23395387.
      Citations: 2     Translation:HumansCells
    90. Lassaunière R, Shalekoff S, Tiemessen CT. A novel FCGR3A intragenic haplotype is associated with increased Fc?RIIIa/CD16a cell surface density and population differences. Hum Immunol. 2013 May; 74(5):627-34. PMID: 23376083.
      Citations: 7     Fields:    Translation:HumansCells
    91. Picton AC, Paximadis M, Tiemessen CT. Contribution of variable CCL3L copy number to CCL3 protein production in two ethnically divergent South African populations. Infect Genet Evol. 2013 Mar; 14:347-56. PMID: 23295355.
      Citations: 3     Fields:    Translation:HumansCells
    92. Paximadis M, Schramm DB, Gray GE, Sherman G, Coovadia A, Kuhn L, Tiemessen CT. Influence of intragenic CCL3 haplotypes and CCL3L copy number in HIV-1 infection in a sub-Saharan African population. Genes Immun. 2013 Jan; 14(1):42-51. PMID: 23151487; PMCID: PMC3554858.
      Citations: 2     Fields:    Translation:HumansCellsPHPublic Health
    93. Picton AC, Paximadis M, Tiemessen CT. CCR5 promoter haplotypes differentially influence CCR5 expression on natural killer and T cell subsets in ethnically divergent HIV-1 uninfected South African populations. Immunogenetics. 2012 Nov; 64(11):795-806. PMID: 22893032.
      Citations: 3     Fields:    Translation:HumansCells
    94. Picton AC, Shalekoff S, Paximadis M, Tiemessen CT. Marked differences in CCR5 expression and activation levels in two South African populations. Immunology. 2012 Aug; 136(4):397-407. PMID: 22509959; PMCID: PMC3401978.
      Citations: 14     Fields:    Translation:HumansCells
    95. Paximadis M, Mathebula TY, Gentle NL, Vardas E, Colvin M, Gray CM, Tiemessen CT, Puren A. Human leukocyte antigen class I (A, B, C) and II (DRB1) diversity in the black and Caucasian South African population. Hum Immunol. 2012 Jan; 73(1):80-92. PMID: 22074999.
      Citations: 31     Fields:    Translation:Humans
    96. Jansen van Vuren P, Tiemessen CT, Paweska JT. Anti-nucleocapsid protein immune responses counteract pathogenic effects of Rift Valley fever virus infection in mice. PLoS One. 2011; 6(9):e25027. PMID: 21949840; PMCID: PMC3174991.
      Citations: 24     Fields:    Translation:AnimalsCellsPHPublic Health
    97. Ramsay M, Tiemessen CT, Choudhury A, Soodyall H. Africa: the next frontier for human disease gene discovery? Hum Mol Genet. 2011 Oct 15; 20(R2):R214-20. PMID: 21908518.
      Citations: 16     Fields:    Translation:Humans
    98. Hong HA, Loubser AS, de Assis Rosa D, Naranbhai V, Carr W, Paximadis M, Lewis DA, Tiemessen CT, Gray CM. Killer-cell immunoglobulin-like receptor genotyping and HLA killer-cell immunoglobulin-like receptor-ligand identification by real-time polymerase chain reaction. Tissue Antigens. 2011 Sep; 78(3):185-94. PMID: 21810083; PMCID: PMC3150492.
      Citations: 8     Fields:    Translation:Humans
    99. Tiemessen CT, Paximadis M, Minevich G, Winchester R, Shalekoff S, Gray GE, Sherman GG, Coovadia AH, Kuhn L. Natural killer cell responses to HIV-1 peptides are associated with more activating KIR genes and HLA-C genes of the C1 allotype. J Acquir Immune Defic Syndr. 2011 Jul 01; 57(3):181-9. PMID: 21407082; PMCID: PMC3280081.
      Citations: 14     Fields:    Translation:HumansCells
    100. Paximadis M, Minevich G, Winchester R, Schramm DB, Gray GE, Sherman GG, Coovadia AH, Kuhn L, Tiemessen CT. KIR-HLA and maternal-infant HIV-1 transmission in sub-Saharan Africa. PLoS One. 2011 Feb 08; 6(2):e16541. PMID: 21346814; PMCID: PMC3035631.
      Citations: 23     Fields:    Translation:HumansCellsPHPublic Health
    101. Tiemessen CT, Shalekoff S, Meddows-Taylor S, Schramm DB, Papathanasopoulos M, Gray G, Sherman G, Coovadia A, Kuhn L. Natural killer cells that respond to human immunodeficiency virus type 1 (HIV-1) peptides are associated with control of HIV-1 infection. J Infect Dis. 2010 Nov 01; 202(9):1444-53. PMID: 20874516; PMCID: PMC3060333.
      Citations: 19     Fields:    Translation:HumansCells
    102. Damelin LH, Paximadis M, Mavri-Damelin D, Birkhead M, Lewis DA, Tiemessen CT. Identification of predominant culturable vaginal Lactobacillus species and associated bacteriophages from women with and without vaginal discharge syndrome in South Africa. J Med Microbiol. 2011 Feb; 60(Pt 2):180-183. PMID: 21030503.
      Citations: 31     Fields:    Translation:HumansCells
    103. Schramm DB, Anthony F, Mathebula B, Sherman G, Coovadia A, Gray GE, Kuhn L, Tiemessen CT. Effect of Maternal HIV-1 Status and Antiretroviral Drugs on Haematological Profiles of South African Infants in Early Life. Open AIDS J. 2010 Aug 12; 4:156-65. PMID: 21258570; PMCID: PMC3024568.
      Citations: 2     
    104. Suchard MS, Mayne E, Green VA, Shalekoff S, Donninger SL, Stevens WS, Gray CM, Tiemessen CT. FOXP3 expression is upregulated in CD4T cells in progressive HIV-1 infection and is a marker of disease severity. PLoS One. 2010 Jul 23; 5(7):e11762. PMID: 20668701; PMCID: PMC2909259.
      Citations: 36     Fields:    Translation:Cells
    105. Damelin LH, Mavri-Damelin D, Klaenhammer TR, Tiemessen CT. Plasmid transduction using bacteriophage Phi(adh) for expression of CC chemokines by Lactobacillus gasseri ADH. Appl Environ Microbiol. 2010 Jun; 76(12):3878-85. PMID: 20418431; PMCID: PMC2893477.
      Citations: 2     Fields:    Translation:HumansCells
    106. Picton AC, Paximadis M, Tiemessen CT. Genetic variation within the gene encoding the HIV-1 CCR5 coreceptor in two South African populations. Infect Genet Evol. 2010 May; 10(4):487-94. PMID: 20206716; PMCID: PMC2877777.
      Citations: 15     Fields:    Translation:HumansCells
    107. Tzitzivacos DB, Tiemessen CT, Stevens WS, Papathanasopoulos MA. Viral genetic determinants of nonprogressive HIV type 1 subtype C infection in antiretroviral drug-naive children. AIDS Res Hum Retroviruses. 2009 Nov; 25(11):1141-8. PMID: 19895210.
      Citations: 10     Fields:    Translation:HumansCellsPHPublic Health
    108. Shalekoff S, Meddows-Taylor S, Schramm DB, Gray G, Sherman G, Coovadia A, Kuhn L, Tiemessen CT. Single-dose nevirapine exposure affects T cell response and cytokine levels in HIV type 1-infected women. AIDS Res Hum Retroviruses. 2009 Oct; 25(10):1049-53. PMID: 19795988; PMCID: PMC2828259.
      Citations: 2     Fields:    Translation:HumansCells
    109. He W, Kulkarni H, Castiblanco J, Shimizu C, Aluyen U, Maldonado R, Carrillo A, Griffin M, Lipsitt A, Beachy L, Shostakovich-Koretskaya L, Mangano A, Sen L, Nibbs RJ, Tiemessen CT, Bolivar H, Bamshad MJ, Clark RA, Burns JC, Dolan MJ, Ahuja SK. Reply to: "Experimental aspects of copy number variant assays at CCL3L1". Nat Med. 2009 Oct; 15(10):1117-20. PMID: 19812563.
      Citations: 14     Fields:    Translation:HumansCells
    110. Tiemessen CT, Shalekoff S, Meddows-Taylor S, Schramm DB, Papathanasopoulos MA, Gray GE, Sherman GG, Coovadia AH, Kuhn L. Cutting Edge: Unusual NK cell responses to HIV-1 peptides are associated with protection against maternal-infant transmission of HIV-1. J Immunol. 2009 May 15; 182(10):5914-8. PMID: 19414742; PMCID: PMC2841685.
      Citations: 38     Fields:    Translation:HumansCellsPHPublic Health
    111. Shalekoff S, Meddows-Taylor S, Gray GE, Sherman GG, Coovadia AH, Kuhn L, Tiemessen CT. Identification of human immunodeficiency virus-1 specific CD8+ and CD4+ T cell responses in perinatally-infected infants and their mothers. AIDS. 2009 Apr 27; 23(7):789-98. PMID: 19293686; PMCID: PMC2761599.
      Citations: 9     Fields:    Translation:HumansCellsPHPublic Health
    112. Paximadis M, Mohanlal N, Gray GE, Kuhn L, Tiemessen CT. Identification of new variants within the two functional genes CCL3 and CCL3L encoding the CCL3 (MIP-1alpha) chemokine: implications for HIV-1 infection. Int J Immunogenet. 2009 Feb; 36(1):21-32. PMID: 19055602.
      Citations: 4     Fields:    Translation:HumansCells
    113. Shalekoff S, Meddows-Taylor S, Schramm DB, Donninger SL, Gray GE, Sherman GG, Coovadia AH, Kuhn L, Tiemessen CT. Host CCL3L1 gene copy number in relation to HIV-1-specific CD4+ and CD8+ T-cell responses and viral load in South African women. J Acquir Immune Defic Syndr. 2008 Jul 01; 48(3):245-54. PMID: 18360285; PMCID: PMC2562935.
      Citations: 22     Fields:    Translation:HumansCells
    114. Mans J, Natarajan K, Balbo A, Schuck P, Eikel D, Hess S, Robinson H, Simic H, Jonjic S, Tiemessen CT, Margulies DH. Cellular expression and crystal structure of the murine cytomegalovirus major histocompatibility complex class I-like glycoprotein, m153. J Biol Chem. 2007 Nov 30; 282(48):35247-58. PMID: 17897947; PMCID: PMC2424207.
      Citations: 12     Fields:    Translation:AnimalsCells
    115. Kuhn L, Schramm DB, Donninger S, Meddows-Taylor S, Coovadia AH, Sherman GG, Gray GE, Tiemessen CT. African infants' CCL3 gene copies influence perinatal HIV transmission in the absence of maternal nevirapine. AIDS. 2007 Aug 20; 21(13):1753-61. PMID: 17690574; PMCID: PMC2386991.
      Citations: 37     Fields:    Translation:HumansPHPublic Health
    116. Meddows-Taylor S, Shalekoff S, Kuhn L, Gray GE, Tiemessen CT. Development of a whole blood intracellular cytokine staining assay for mapping CD4(+) and CD8(+) T-cell responses across the HIV-1 genome. J Virol Methods. 2007 Sep; 144(1-2):115-21. PMID: 17543395; PMCID: PMC2292247.
      Citations: 12     Fields:    Translation:HumansCells
    117. Gray GE, Tiemessen CT, de Bruyn G. Immune-based prevention of mother-to-child HIV-1 transmission. Curr Opin Mol Ther. 2007 Apr; 9(2):168-75. PMID: 17458171.
      Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
    118. Tiemessen CT, Kuhn L. CC chemokines and protective immunity: insights gained from mother-to-child transmission of HIV. Nat Immunol. 2007 Mar; 8(3):219-22. PMID: 17304227; PMCID: PMC1866187.
      Citations: 9     Fields:    Translation:HumansAnimalsPHPublic Health
    119. Schramm DB, Meddows-Taylor S, Gray GE, Kuhn L, Tiemessen CT. Low maternal viral loads and reduced granulocyte-macrophage colony-stimulating factor levels characterize exposed, uninfected infants who develop protective human immunodeficiency virus type 1-specific responses. Clin Vaccine Immunol. 2007 Apr; 14(4):348-54. PMID: 17301218; PMCID: PMC1865610.
      Citations: 6     Fields:    Translation:HumansCells
    120. Schramm DB, Kuhn L, Gray GE, Tiemessen CT. In vivo effects of HIV-1 exposure in the presence and absence of single-dose nevirapine on cellular plasma activation markers of infants born to HIV-1-seropositive mothers. J Acquir Immune Defic Syndr. 2006 Aug 15; 42(5):545-53. PMID: 16837862; PMCID: PMC2367220.
      Citations: 19     Fields:    Translation:HumansCells
    121. Meddows-Taylor S, Donninger SL, Paximadis M, Schramm DB, Anthony FS, Gray GE, Kuhn L, Tiemessen CT. Reduced ability of newborns to produce CCL3 is associated with increased susceptibility to perinatal human immunodeficiency virus 1 transmission. J Gen Virol. 2006 Jul; 87(Pt 7):2055-2065. PMID: 16760409; PMCID: PMC2365885.
      Citations: 27     Fields:    Translation:HumansCellsPHPublic Health
    122. Van Rie A, Madhi SA, Heera JR, Meddows-Taylor S, Wendelboe AM, Anthony F, Violari A, Tiemessen CT. Gamma interferon production in response to Mycobacterium bovis BCG and Mycobacterium tuberculosis antigens in infants born to human immunodeficiency virus-infected mothers. Clin Vaccine Immunol. 2006 Feb; 13(2):246-52. PMID: 16467333; PMCID: PMC1391928.
      Citations: 24     Fields:    Translation:HumansCells
    123. Tiemessen CT, Kuhn L. Immune pathogenesis of pediatric HIV-1 infection. Curr HIV/AIDS Rep. 2006 Feb; 3(1):13-9. PMID: 16522254; PMCID: PMC2329811.
      Citations: 13     Fields:    Translation:HumansCellsPHPublic Health
    124. Smit SB, Hardie D, Tiemessen CT. Measles virus genotype B2 is not inactive: evidence of continued circulation in Africa. J Med Virol. 2005 Dec; 77(4):550-7. PMID: 16254960.
      Citations: 6     Fields:    Translation:HumansCellsPHPublic Health
    125. Agenbach E, Tiemessen CT, Venter M. Amino acid variation within the fusion protein of respiratory syncytial virus subtype A and B strains during annual epidemics in South Africa. Virus Genes. 2005 Mar; 30(2):267-78. PMID: 15744582.
      Citations: 10     Fields:    Translation:HumansCellsPHPublic Health
    126. Meddows-Taylor S, Tiemessen CT. Age-related changes in polymorphonuclear neutrophil characteristics in infants born to human immunodeficiency virus type 1 seropositive mothers. Pediatr Allergy Immunol. 2004 Apr; 15(2):172-82. PMID: 15059196.
      Citations: 1     Fields:    Translation:HumansCells
    127. Meddows-Taylor S, Papathanasopoulos MA, Kuhn L, Meyers TM, Tiemessen CT. Detection of human immunodeficiency virus type 1 envelope peptide- stimulated T-helper cell responses and variations in the corresponding regions of viral isolates among vertically infected children. Virus Genes. 2004 Apr; 28(3):311-8. PMID: 15266112; PMCID: PMC2364720.
      Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
    128. Shalekoff S, Gray GE, Tiemessen CT. Age-related changes in expression of CXCR4 and CCR5 on peripheral blood leukocytes from uninfected infants born to human immunodeficiency virus type 1-infected mothers. Clin Diagn Lab Immunol. 2004 Jan; 11(1):229-34. PMID: 14715575; PMCID: PMC321339.
      Citations: 15     Fields:    Translation:HumansCellsPHPublic Health
    129. Venter M, Rock M, Puren AJ, Tiemessen CT, Crowe JE. Respiratory syncytial virus nucleoprotein-specific cytotoxic T-cell epitopes in a South African population of diverse HLA types are conserved in circulating field strains. J Virol. 2003 Jul; 77(13):7319-29. PMID: 12805430; PMCID: PMC164818.
      Citations: 20     Fields:    Translation:HumansCellsPHPublic Health
    130. Shalekoff S, Tiemessen CT. Circulating levels of stromal cell-derived factor 1alpha and interleukin 7 in HIV type 1 infection and pulmonary tuberculosis are reciprocally related to CXCR4 expression on peripheral blood leukocytes. AIDS Res Hum Retroviruses. 2003 Jun; 19(6):461-8. PMID: 12882655.
      Citations: 3     Fields:    Translation:HumansCells
    131. Shalekoff S, Tiemessen CT. CCR5 delta32 heterozygosity is associated with an increase in CXCR4 cell surface expression. AIDS Res Hum Retroviruses. 2003 Jun; 19(6):531-3. PMID: 12882661.
      Citations: 6     Fields:    Translation:HumansCells
    132. Hunt GM, Papathanasopoulos MA, Gray GE, Tiemessen CT. Characterisation of near-full length genome sequences of three South African human immunodeficiency virus type 1 subtype C isolates. Virus Genes. 2003 Jan; 26(1):49-56. PMID: 12680693.
      Citations: 1     Fields:    Translation:HumansCells
    133. Papathanasopoulos MA, Hunt GM, Tiemessen CT. Evolution and diversity of HIV-1 in Africa--a review. Virus Genes. 2003; 26(2):151-63. PMID: 12803467.
      Citations: 17     Fields:    Translation:HumansCells
    134. Bredell H, Hunt G, Casteling A, Cilliers T, Rademeyer C, Coetzer M, Miller S, Johnson D, Tiemessen CT, Martin DJ, Williamson C, Morris L. HIV-1 Subtype A, D, G, AG and unclassified sequences identified in South Africa. AIDS Res Hum Retroviruses. 2002 Jun 10; 18(9):681-3. PMID: 12079566.
      Citations: 10     Fields:    Translation:HumansCells
    135. Sherman GG, Scott LE, Galpin JS, Kuhn L, Tiemessen CT, Simmank K, Meddows-Taylor S, Meyers TM. CD38 expression on CD8(+) T cells as a prognostic marker in vertically HIV-infected pediatric patients. Pediatr Res. 2002 Jun; 51(6):740-5. PMID: 12032270.
      Citations: 12     Fields:    Translation:HumansCellsPHPublic Health
    136. Kuhn L, Meddows-Taylor S, Gray G, Tiemessen C. Human immunodeficiency virus (HIV)-specific cellular immune responses in newborns exposed to HIV in utero. Clin Infect Dis. 2002 Jan 15; 34(2):267-76. PMID: 11740717.
      Citations: 34     Fields:    Translation:HumansPHPublic Health
    137. Shalekoff S, Pendle S, Johnson D, Martin DJ, Tiemessen CT. Distribution of the human immunodeficiency virus coreceptors CXCR4 and CCR5 on leukocytes of persons with human immunodeficiency virus type 1 infection and pulmonary tuberculosis: implications for pathogenesis. J Clin Immunol. 2001 Nov; 21(6):390-401. PMID: 11811784.
      Citations: 11     Fields:    Translation:HumansCells
    138. Venter M, Madhi SA, Tiemessen CT, Schoub BD. Genetic diversity and molecular epidemiology of respiratory syncytial virus over four consecutive seasons in South Africa: identification of new subgroup A and B genotypes. J Gen Virol. 2001 Sep; 82(Pt 9):2117-2124. PMID: 11514720.
      Citations: 104     Fields:    Translation:HumansCells
    139. Kuhn L, Meyers TM, Meddows-Taylor S, Simmank K, Sherman GG, Tiemessen CT. Human immunodeficiency virus type 1 envelope-stimulated interleukin-2 production and survival of infected children with severe and mild clinical disease. J Infect Dis. 2001 Sep 15; 184(6):691-8. PMID: 11517429.
      Citations: 3     Fields:    Translation:HumansCells
    140. Meddows-Taylor S, Meyers TM, Kuhn L, Tiemessen CT. Interleukin-8 concentrations in the peripheral circulation of human immunodeficiency virus type 1-infected children suggest blunted chemokine responses. Pediatr Infect Dis J. 2001 Aug; 20(8):819-20. PMID: 11734757.
      Citations:    Fields:    Translation:HumansCells
    141. Tiemessen CT, Shalekoff S, Meddows-Taylor S, Martin DJ. Antituberculosis treatment: increasing evidence for drug effects on innate cellular immunity. Clin Diagn Lab Immunol. 2001 Jul; 8(4):686-9. PMID: 11427411; PMCID: PMC96127.
      Citations: 3     Fields:    Translation:HumansCells
    142. Meddows-Taylor S, Kuhn L, Meyers TM, Tiemessen CT. Altered expression of L-selectin (CD62L) on polymorphonuclear neutrophils of children vertically infected with human immunodeficiency virus type 1. J Clin Immunol. 2001 Jul; 21(4):286-92. PMID: 11506199.
      Citations: 5     Fields:    Translation:HumansCellsPHPublic Health
    143. Shalekoff S, Tiemessen CT. Duration of sample storage dramatically alters expression of the human immunodeficiency virus coreceptors CXCR4 and CCR5. Clin Diagn Lab Immunol. 2001 Mar; 8(2):432-6. PMID: 11238234; PMCID: PMC96075.
      Citations: 6     Fields:    Translation:HumansCells
    144. Kuhn L, Meddows-Taylor S, Gray G, Trabattoni D, Clerici M, Shearer GM, Tiemessen C. Reduced HIV-stimulated T-helper cell reactivity in cord blood with short-course antiretroviral treatment for prevention of maternal-infant transmission. Clin Exp Immunol. 2001 Mar; 123(3):443-50. PMID: 11298132; PMCID: PMC1906013.
      Citations: 8     Fields:    Translation:HumansCellsPHPublic Health
    145. Meddows-Taylor S, Pendle S, Tiemessen CT. Altered expression of CD88 and associated impairment of complement 5a-induced neutrophil responses in human immunodeficiency virus type 1-infected patients with and without pulmonary tuberculosis. J Infect Dis. 2001 Feb 15; 183(4):662-5. PMID: 11170995.
      Citations: 3     Fields:    Translation:HumansCells
    146. Meddows-Taylor S, Kuhn L, Meyers TM, Sherman G, Tiemessen CT. Defective neutrophil degranulation induced by interleukin-8 and complement 5a and down-regulation of associated receptors in children vertically infected with human immunodeficiency virus type 1. Clin Diagn Lab Immunol. 2001 Jan; 8(1):21-30. PMID: 11139191; PMCID: PMC96006.
      Citations: 5     Fields:    Translation:HumansCellsPHPublic Health
    147. Meyers TM, Kuhn L, Meddows-Taylor S, Simmank K, Sherman GG, Tiemessen CT. T-helper cell responses among HIV-infected children in Soweto, South Africa. Ann N Y Acad Sci. 2000 Nov; 918:373-6. PMID: 11131729.
      Citations:    Fields:    Translation:HumansCellsPHPublic Health
    148. Tiemessen CT, Kilroe B, Martin DJ. Interleukin-8 fails to induce human immunodeficiency virus-1 expression in chronically infected promonocytic U1 cells but differentially modulates induction by proinflammatory cytokines. Immunology. 2000 Sep; 101(1):140-6. PMID: 11012765; PMCID: PMC2327060.
      Citations: 3     Fields:    Translation:HumansCells
    149. Gao PS, Fujishima S, Mao XQ, Remus N, Kanda M, Enomoto T, Dake Y, Bottini N, Tabuchi M, Hasegawa N, Yamaguchi K, Tiemessen C, Hopkin JM, Shirakawa T, Kishi F. Genetic variants of NRAMP1 and active tuberculosis in Japanese populations. International Tuberculosis Genetics Team. Clin Genet. 2000 Jul; 58(1):74-6. PMID: 10945666.
      Citations: 24     Fields:    Translation:Humans
    150. Tiemessen CT, Martin DJ. Cytokine-induced interleukin-8 production is depressed in chronic as opposed to acute human immunodeficiency virus 1 infection of promonocytic cells. Acta Virol. 2000 Jun-Aug; 44(3):193-8. PMID: 11155365.
      Citations:    Fields:    Translation:HumansCells
    151. Bredell H, Hunt G, Morgan B, Tiemessen CT, Martin DJ, Morris L. Identification of HIV type 1 intersubtype recombinants in South Africa using env and gag heteroduplex mobility assays. AIDS Res Hum Retroviruses. 2000 Mar 20; 16(5):493-7. PMID: 10772535.
      Citations: 4     Fields:    Translation:HumansCellsPHPublic Health
    152. Hunt G, Tiemessen CT. Occurrence of additional NF-kappaB-binding motifs in the long terminal repeat region of South African HIV type 1 subtype C isolates. AIDS Res Hum Retroviruses. 2000 Feb 10; 16(3):305-6. PMID: 10710220.
      Citations: 10     Fields:    Translation:HumansCells
    153. Michelow IC, Nicol M, Tiemessen C, Chezzi C, Pettifor JM. Value of cerebrospinal fluid leukocyte aggregation in distinguishing the causes of meningitis in children. Pediatr Infect Dis J. 2000 Jan; 19(1):66-72. PMID: 10643853.
      Citations: 6     Fields:    Translation:HumansCellsCTClinical Trials
    154. Meddows-Taylor S, Martin DJ, Tiemessen CT. Impaired interleukin-8-induced degranulation of polymorphonuclear neutrophils from human immunodeficiency virus type 1-infected individuals. Clin Diagn Lab Immunol. 1999 May; 6(3):345-51. PMID: 10225834; PMCID: PMC103721.
      Citations: 7     Fields:    Translation:HumansCells
    155. Meddows-Taylor S, Martin DJ, Tiemessen CT. Dysregulated production of interleukin-8 in individuals infected with human immunodeficiency virus type 1 and Mycobacterium tuberculosis. Infect Immun. 1999 Mar; 67(3):1251-60. PMID: 10024568; PMCID: PMC96454.
      Citations: 10     Fields:    Translation:HumansCells
    156. Shalekoff S, Page-Shipp L, Tiemessen CT. Effects of anticoagulants and temperature on expression of activation markers CD11b and HLA-DR on human leukocytes. Clin Diagn Lab Immunol. 1998 Sep; 5(5):695-702. PMID: 9729538; PMCID: PMC95642.
      Citations: 12     Fields:    Translation:HumansCells
    157. Meddows-Taylor S, Martin DJ, Tiemessen CT. Reduced expression of interleukin-8 receptors A and B on polymorphonuclear neutrophils from persons with human immunodeficiency virus type 1 disease and pulmonary tuberculosis. J Infect Dis. 1998 Apr; 177(4):921-30. PMID: 9534964.
      Citations: 11     Fields:    Translation:HumansCells
    158. Tiemessen CT, Kilroe B, Martin DJ. Interleukin-4 regulation of cytokine-induced HIV1 and interleukin-8 expression in promonocytic U1 cells is concentration- and cytokine-dependent. Res Virol. 1998 Jan-Feb; 149(1):21-7. PMID: 9561561.
      Citations: 1     Fields:    Translation:HumansCells
    159. Shalekoff S, Tiemessen CT, Gray CM, Martin DJ. Depressed phagocytosis and oxidative burst in polymorphonuclear leukocytes from individuals with pulmonary tuberculosis with or without human immunodeficiency virus type 1 infection. Clin Diagn Lab Immunol. 1998 Jan; 5(1):41-4. PMID: 9455878; PMCID: PMC121389.
      Citations: 14     Fields:    Translation:HumansCells
    160. Meddows-Taylor S, Martin DJ, Tiemessen CT. Altered expression of Fc gammaRIII (CD16) on polymorphonuclear neutrophils from individuals with human immunodeficiency virus type 1 disease and pulmonary tuberculosis. Clin Diagn Lab Immunol. 1997 Nov; 4(6):789-91. PMID: 9384310; PMCID: PMC170661.
      Citations: 4     Fields:    Translation:HumansCells
    161. Tiemessen CT, Nel MJ, Kidd AH. Adenovirus 41 replication: cell-related differences in viral gene transcription. Mol Cell Probes. 1996 Aug; 10(4):279-87. PMID: 8865176.
      Citations: 2     Fields:    Translation:HumansCells
    162. Tiemessen CT, Nel MJ. Detection and typing of subgroup F adenoviruses using the polymerase chain reaction. J Virol Methods. 1996 May; 59(1-2):73-82. PMID: 8793832.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    163. Tiemessen CT, Kidd AH. The subgroup F adenoviruses. J Gen Virol. 1995 Mar; 76 ( Pt 3):481-97. PMID: 7897343.
      Citations: 18     Fields:    Translation:HumansCells
    164. Tiemessen CT, Shalekoff S, Morris L, Becker Y, Martin DJ. Characterization of human blood dendritic cells: cytokine profiles. Adv Exp Med Biol. 1995; 378:85-7. PMID: 8526151.
      Citations:    Fields:    Translation:HumansCells
    165. Tiemessen CT, Kidd AH. Adenovirus type 40 and 41 growth in vitro: host range diversity reflected by differences in patterns of DNA replication. J Virol. 1994 Feb; 68(2):1239-44. PMID: 8289359; PMCID: PMC236569.
      Citations: 11     Fields:    Translation:HumansCells
    166. Kidd AH, Tiemessen CT. Characterization of a single SA7-like VA RNA gene in subgroup F adenoviruses. J Gen Virol. 1993 Aug; 74 ( Pt 8):1621-6. PMID: 8345354.
      Citations: 2     Fields:    Translation:Cells
    167. Tiemessen CT, Ujfalusi M, Kidd AH. Subgroup F adenovirus growth in foetal intestinal organ cultures. Arch Virol. 1993; 132(1-2):193-200. PMID: 8352657.
      Citations: 1     Fields:    Translation:HumansCells
    168. Tiemessen CT, Kidd AH. Sensitivity of subgroup F adenoviruses to interferon. Arch Virol. 1993; 128(1-2):1-13. PMID: 7678191.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    169. Kidd AH, Erasmus MJ, Tiemessen CT. Fiber sequence heterogeneity in subgroup F adenoviruses. Virology. 1990 Nov; 179(1):139-50. PMID: 2219717.
      Citations: 14     Fields:    Translation:HumansCells
    170. Tiemessen CT, Kidd AH. Adenovirus 41 growth in semi-permissive cells shows multiple-hit kinetics. Arch Virol. 1990; 110(3-4):239-45. PMID: 2317153.
      Citations: 1     Fields:    Translation:HumansCells
    171. Tiemessen CT, Wegerhoff FO, Erasmus MJ, Kidd AH. Infection by enteric adenoviruses, rotaviruses, and other agents in a rural African environment. J Med Virol. 1989 Jul; 28(3):176-82. PMID: 2547021; PMCID: PMC7167002.
      Citations: 10     Fields:    Translation:HumansCells
    172. Tiemessen CT, Kidd AH. Helper function of adenovirus 2 for adenovirus 41 antigen synthesis in semi-permissive and non-permissive cells. Arch Virol. 1988; 103(3-4):207-18. PMID: 3063232.
      Citations: 7     Fields:    Translation:HumansCells
    173. Kidd AH, Rosenblatt A, Besselaar TG, Erasmus MJ, Tiemessen CT, Berkowitz FE, Schoub BD. Characterization of rotaviruses and subgroup F adenoviruses from acute summer gastroenteritis in South Africa. J Med Virol. 1986 Feb; 18(2):159-68. PMID: 3005488.
      Citations: 10     Fields:    Translation:HumansCells
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