"Disulfides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Chemical groups containing the covalent disulfide bonds -S-S-. The sulfur atoms can be bound to inorganic or organic moieties.
| Descriptor ID |
D004220
|
| MeSH Number(s) |
D01.248.497.158.874.390 D01.875.350.850.150 D02.886.520.150
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Disulfides".
Below are MeSH descriptors whose meaning is more specific than "Disulfides".
This graph shows the total number of publications written about "Disulfides" by people in this website by year, and whether "Disulfides" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Disulfides" by people in Profiles.
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Redox exchange of the disulfides of human two-domain CD4 regulates the conformational dynamics of each domain, providing insight into its mechanisms of control. Biochem Biophys Res Commun. 2018 03 04; 497(2):811-817.
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Human CD4 Metastability Is a Function of the Allosteric Disulfide Bond in Domain 2. Biochemistry. 2016 Apr 19; 55(15):2227-37.
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Disulphide-thiol chemistry: a multi-faceted tool for macromolecular design and synthesis of polyfunctional materials for specialized drug delivery. Curr Drug Deliv. 2015; 12(3):282-98.
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Disulfide reduction in CD4 domain 1 or 2 is essential for interaction with HIV glycoprotein 120 (gp120), which impairs thioredoxin-driven CD4 dimerization. J Biol Chem. 2014 Apr 11; 289(15):10455-10465.
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Stabilization of HIV-1 gp120-CD4 receptor complex through targeted interchain disulfide exchange. J Biol Chem. 2010 Aug 13; 285(33):25743-52.