"Receptors, CXCR4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
CXCR receptors with specificity for CXCL12 CHEMOKINE. The receptors may play a role in HEMATOPOIESIS regulation and can also function as coreceptors for the HUMAN IMMUNODEFICIENCY VIRUS.
| Descriptor ID |
D019718
|
| MeSH Number(s) |
D12.776.543.750.695.160.500.400 D12.776.543.750.705.852.125.500.400 D12.776.543.750.830.700.650
|
| Concept/Terms |
Receptors, CXCR4- Receptors, CXCR4
- LESTR Receptor
- CXC Chemokine Receptor 4
- Fusin
- CXCR4 Receptor
- Receptor, CXCR4
- CXCR4 Receptors
- Leukocyte-Derived Seven-Transmembrane Domain Receptor
- Leukocyte Derived Seven Transmembrane Domain Receptor
- Receptor, LESTR
|
Below are MeSH descriptors whose meaning is more general than "Receptors, CXCR4".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Chemokine [D12.776.543.750.695.160]
- Receptors, CXCR [D12.776.543.750.695.160.500]
- Receptors, CXCR4 [D12.776.543.750.695.160.500.400]
- Receptors, Immunologic [D12.776.543.750.705]
- Receptors, Cytokine [D12.776.543.750.705.852]
- Receptors, Chemokine [D12.776.543.750.705.852.125]
- Receptors, CXCR [D12.776.543.750.705.852.125.500]
- Receptors, CXCR4 [D12.776.543.750.705.852.125.500.400]
- Receptors, Virus [D12.776.543.750.830]
- Receptors, HIV [D12.776.543.750.830.700]
- Receptors, CXCR4 [D12.776.543.750.830.700.650]
Below are MeSH descriptors whose meaning is more specific than "Receptors, CXCR4".
This graph shows the total number of publications written about "Receptors, CXCR4" by people in this website by year, and whether "Receptors, CXCR4" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 2 | 0 | 2 |
| 2002 | 1 | 1 | 2 |
| 2003 | 3 | 0 | 3 |
| 2004 | 1 | 1 | 2 |
| 2006 | 1 | 1 | 2 |
| 2007 | 0 | 2 | 2 |
| 2008 | 2 | 0 | 2 |
| 2011 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Receptors, CXCR4" by people in Profiles.
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Immune activation correlates with and predicts CXCR4 co-receptor tropism switch in HIV-1 infection. Sci Rep. 2020 09 28; 10(1):15866.
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Comparisons of Human Immunodeficiency Virus Type 1 Envelope Variants in Blood and Genital Fluids near the Time of Male-to-Female Transmission. J Virol. 2019 07 01; 93(13).
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HIV-1 subtype C unproductively infects human cardiomyocytes in vitro and induces apoptosis mitigated by an anti-Gp120 aptamer. PLoS One. 2014; 9(10):e110930.
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Differences are evident within the CXCR4-CXCL12 axis between ethnically divergent South African populations. Cytokine. 2013 Mar; 61(3):792-800.
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Extreme genetic divergence is required for coreceptor switching in HIV-1 subtype C. J Acquir Immune Defic Syndr. 2011 Jan 01; 56(1):9-15.
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Genotypic characterization and comparison of full-length envelope glycoproteins from South African HIV type 1 subtype C primary isolates that utilize CCR5 and/or CXCR4. AIDS Res Hum Retroviruses. 2008 May; 24(5):743-51.
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Emergence of X4 usage among HIV-1 subtype C: evidence for an evolving epidemic in South Africa. AIDS. 2008 Apr 23; 22(7):896-9.
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Longitudinal analysis of HIV type 1 subtype C envelope sequences from South Africa. AIDS Res Hum Retroviruses. 2007 Feb; 23(2):316-21.
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Phenotypic characterization of HIV type 1 isolates from Ghana. AIDS Res Hum Retroviruses. 2007 Jan; 23(1):144-52.
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Genetic characteristics of the V3 region associated with CXCR4 usage in HIV-1 subtype C isolates. Virology. 2006 Dec 5-20; 356(1-2):95-105.