"Interleukin-8" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the CXC chemokine family that plays a role in the regulation of the acute inflammatory response. It is secreted by variety of cell types and induces CHEMOTAXIS of NEUTROPHILS and other inflammatory cells.
| Descriptor ID |
D016209
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| MeSH Number(s) |
D12.644.276.374.200.120.800 D12.644.276.374.465.312 D12.776.467.374.200.120.800 D12.776.467.374.465.246 D23.125.300.120.800 D23.469.200.120.800 D23.529.374.200.120.800 D23.529.374.465.312
|
| Concept/Terms |
Interleukin-8- Interleukin-8
- Interleukin 8
- IL8
- Monocyte-Derived Neutrophil Chemotactic Factor
- Neutrophil Activation Factor
- Neutrophil-Activating Peptide, Lymphocyte-Derived
- Lymphocyte-Derived Neutrophil-Activating Peptide
- Neutrophil Activating Peptide, Lymphocyte Derived
- Neutrophil-Activating Peptide, Monocyte-Derived
- Monocyte-Derived Neutrophil-Activating Peptide
- Neutrophil Activating Peptide, Monocyte Derived
- Alveolar Macrophage Chemotactic Factor-I
- Alveolar Macrophage Chemotactic Factor I
- AMCF-I
- Anionic Neutrophil-Activating Peptide
- Anionic Neutrophil Activating Peptide
- Neutrophil-Activating Peptide, Anionic
- Peptide, Anionic Neutrophil-Activating
- Chemokine CXCL8
- CXCL8, Chemokine
- Chemokines, CXCL8
- CXCL8 Chemokines
- Chemotactic Factor, Macrophage-Derived
- Chemotactic Factor, Macrophage Derived
- Macrophage-Derived Chemotactic Factor
- Chemotactic Factor, Neutrophil
- Neutrophil Chemotactic Factor
- Chemotactic Factor, Neutrophil, Monocyte-Derived
- CXCL8 Chemokine
- Chemokine, CXCL8
- Granulocyte Chemotactic Peptide-Interleukin-8
- Chemotactic Peptide-Interleukin-8, Granulocyte
- Granulocyte Chemotactic Peptide Interleukin 8
- IL-8
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Below are MeSH descriptors whose meaning is more general than "Interleukin-8".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-8".
This graph shows the total number of publications written about "Interleukin-8" by people in this website by year, and whether "Interleukin-8" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 2 | 2 | 4 |
| 1999 | 2 | 0 | 2 |
| 2000 | 2 | 0 | 2 |
| 2001 | 2 | 0 | 2 |
| 2002 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Interleukin-8" by people in Profiles.
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Interleukin-8 genetic diversity, haplotype structure and production differ in two ethnically distinct South African populations. Cytokine. 2021 07; 143:155489.
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Effects of Tobacco Usage and Antiretroviral Therapy on Biomarkers of Systemic Immune Activation in HIV-Infected Participants. Mediators Inflamm. 2018; 2018:8357109.
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The effect of abdominal obesity on insulin sensitivity and serum lipid and cytokine concentrations in African women. Clin Endocrinol (Oxf). 2006 May; 64(5):535-41.
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Pneumolysin-mediated activation of NFkappaB in human neutrophils is antagonized by docosahexaenoic acid. Clin Exp Immunol. 2005 May; 140(2):274-81.
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Pneumolysin activates the synthesis and release of interleukin-8 by human neutrophils in vitro. J Infect Dis. 2002 Aug 15; 186(4):562-5.
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Interleukin-8 concentrations in the peripheral circulation of human immunodeficiency virus type 1-infected children suggest blunted chemokine responses. Pediatr Infect Dis J. 2001 Aug; 20(8):819-20.
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Defective neutrophil degranulation induced by interleukin-8 and complement 5a and down-regulation of associated receptors in children vertically infected with human immunodeficiency virus type 1. Clin Diagn Lab Immunol. 2001 Jan; 8(1):21-30.
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Interleukin-8 fails to induce human immunodeficiency virus-1 expression in chronically infected promonocytic U1 cells but differentially modulates induction by proinflammatory cytokines. Immunology. 2000 Sep; 101(1):140-6.
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Cytokine-induced interleukin-8 production is depressed in chronic as opposed to acute human immunodeficiency virus 1 infection of promonocytic cells. Acta Virol. 2000 Jun-Aug; 44(3):193-8.
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Impaired interleukin-8-induced degranulation of polymorphonuclear neutrophils from human immunodeficiency virus type 1-infected individuals. Clin Diagn Lab Immunol. 1999 May; 6(3):345-51.