"HLA-C Antigens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Class I human histocompatibility (HLA) antigens encoded by a small cluster of structural genes at the C locus on chromosome 6. They have significantly lower immunogenicity than the HLA-A and -B determinants and are therefore of minor importance in donor/recipient crossmatching. Their primary role is their high-risk association with certain disease manifestations (e.g., spondylarthritis, psoriasis, multiple myeloma).
| Descriptor ID |
D015236
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| MeSH Number(s) |
D12.776.395.550.489.600 D12.776.543.550.439.600 D23.050.301.500.100.600 D23.050.301.500.450.390 D23.050.705.552.100.600 D23.050.705.552.450.390
|
| Concept/Terms |
HLA-C Antigens- HLA-C Antigens
- HLA C Antigens
- HLA-C
- Antigens, HLA-C
- Antigens, HLA C
|
Below are MeSH descriptors whose meaning is more general than "HLA-C Antigens".
Below are MeSH descriptors whose meaning is more specific than "HLA-C Antigens".
This graph shows the total number of publications written about "HLA-C Antigens" by people in this website by year, and whether "HLA-C Antigens" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 2 | 0 | 2 |
| 2013 | 1 | 0 | 1 |
| 2017 | 2 | 0 | 2 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "HLA-C Antigens" by people in Profiles.
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Lack of association of KIR2DL1-R245 and KIR2DL1-C245 with HIV-1 control in black South Africans with HLA-C2. Hum Immunol. 2021 Aug; 82(8):600-607.
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Human leukocyte antigen class I (A, B and C) allele and haplotype variation in a South African Indian population. Hum Immunol. 2017 Jul - Aug; 78(7-8):468-470.
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Human leukocyte antigen class I (A, B and C) allele and haplotype variation in a South African Mixed ancestry population. Hum Immunol. 2017 May - Jun; 78(5-6):399-400.
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Genetic variability in markers of HLA-C expression in two diverse South African populations. PLoS One. 2013; 8(7):e67780.
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Human leukocyte antigen class I (A, B, C) and II (DRB1) diversity in the black and Caucasian South African population. Hum Immunol. 2012 Jan; 73(1):80-92.
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Natural killer cell responses to HIV-1 peptides are associated with more activating KIR genes and HLA-C genes of the C1 allotype. J Acquir Immune Defic Syndr. 2011 Jul 01; 57(3):181-9.