"Drug Design" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The molecular designing of drugs for specific purposes (such as DNA-binding, enzyme inhibition, anti-cancer efficacy, etc.) based on knowledge of molecular properties such as activity of functional groups, molecular geometry, and electronic structure, and also on information cataloged on analogous molecules. Drug design is generally computer-assisted molecular modeling and does not include pharmacokinetics, dosage analysis, or drug administration analysis.
| Descriptor ID |
D015195
|
| MeSH Number(s) |
E05.295.500 H01.158.703.007.675.500 H01.181.466.675.500
|
| Concept/Terms |
Drug Design- Drug Design
- Design, Drug
- Designs, Drug
- Drug Designs
Drug Modeling- Drug Modeling
- Drug Modelings
- Modeling, Drug
- Modelings, Drug
|
Below are MeSH descriptors whose meaning is more general than "Drug Design".
Below are MeSH descriptors whose meaning is more specific than "Drug Design".
This graph shows the total number of publications written about "Drug Design" by people in this website by year, and whether "Drug Design" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2011 | 0 | 2 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2015 | 2 | 0 | 2 |
| 2016 | 3 | 1 | 4 |
| 2017 | 0 | 1 | 1 |
| 2018 | 2 | 1 | 3 |
| 2019 | 0 | 1 | 1 |
| 2021 | 2 | 0 | 2 |
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Below are the most recent publications written about "Drug Design" by people in Profiles.
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Importance of Surface Topography in Both Biological Activity and Catalysis of Nanomaterials: Can Catalysis by Design Guide Safe by Design? Int J Mol Sci. 2021 Aug 03; 22(15).
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Design and synthesis of quinoline-pyrimidine inspired hybrids as potential plasmodial inhibitors. Eur J Med Chem. 2021 May 05; 217:113330.
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Patented therapeutic approaches targeting LRP/LR for cancer treatment. Expert Opin Ther Pat. 2019 Dec; 29(12):987-1009.
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Covalent simulations of covalent/irreversible enzyme inhibition in drug discovery: a reliable technical protocol. Future Med Chem. 2018 10; 10(19):2265-2275.
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An update on the discovery and development of selective heat shock protein inhibitors as anti-cancer therapy. Expert Opin Drug Discov. 2018 10; 13(10):903-918.
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Covalent Inhibition in Drug Discovery: Filling the Void in Literature. Curr Top Med Chem. 2018; 18(13):1135-1145.
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Targeted nanotechnologies for cancer intervention: a patent review (2010-2016). Expert Opin Ther Pat. 2017 Sep; 27(9):1005-1019.
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Design, synthesis and biological evaluation of 6-aryl-1,6-dihydro-1,3,5-triazine-2,4-diamines as antiplasmodial antifolates. Org Biomol Chem. 2016 Aug 16; 14(33):7899-911.
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Multi-target therapeutics for neuropsychiatric and neurodegenerative disorders. Drug Discov Today. 2016 12; 21(12):1886-1914.
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Design of an In Situ Cross-Linked Eutectic Tablet for Enhanced Delivery of Gastro-Sensitive Proteins and Peptides. J Pharm Sci. 2016 07; 105(7):2086-98.