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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Pal K, Lala S, Agarwal P, Patel TS, Legac J, Rahman MA, Ahmedi S, Shahid N, Singh S, Kumari K, Madhav H, Sen A, Manzoor N, Dixit BC, Van Zyl R, Rosenthal PJ, Hoda N. Naphthyl bearing 1,3,4-thiadiazoleacetamides targeting the parasitic folate pathway as anti-infectious agents: in silico, synthesis, and biological approach. RSC Med Chem. 2023 Dec 13; 14(12):2768-2781. PMID: 38107179; PMCID: PMC10718588.
      Citations: 1     
    2. Rants'o TA, Koekemoer LL, van Zyl RL. Bioactivity of select essential oil constituents against life stages of Anopheles arabiensis (Diptera: Culicidae). Exp Parasitol. 2023 Aug; 251:108569. PMID: 37330107.
      Citations:    Fields:    Translation:AnimalsPHPublic Health
    3. Rants'o TA, Koekemoer LL, van Zyl RL. The insecticidal activity of essential oil constituents against pyrethroid-resistant Anopheles funestus (Diptera: Culicidae). Parasitol Int. 2023 Aug; 95:102749. PMID: 36898498.
      Citations:    Fields:    Translation:AnimalsPHPublic Health
    4. Bashar MA, van Zyl RL, Miot J, McInerney PA. A content analysis of two african medical schools' antibiotic stewardship curricula. Educ Health (Abingdon). 2023 Jan-Apr; 36(1):4-13. PMID: 38047342.
      Citations:    Fields:    Translation:Humans
    5. Rants'o TA, Koekemoer LL, van Zyl RL. In vitro and in silico analysis of the Anopheles anticholinesterase activity of terpenoids. Parasitol Int. 2023 Apr; 93:102713. PMID: 36455706.
      Citations: 1     Fields:    Translation:AnimalsPHPublic Health
    6. Rants'o TA, van Greunen DG, van der Westhuizen CJ, Riley DL, Panayides JL, Koekemoer LL, van Zyl RL. The in silico and in vitro analysis of donepezil derivatives for Anopheles acetylcholinesterase inhibition. PLoS One. 2022; 17(11):e0277363. PMID: 36350894; PMCID: PMC9645637.
      Citations: 1     Fields:    Translation:HumansAnimalsPHPublic Health
    7. Rants'o TA, Koekemoer LL, Panayides JL, van Zyl RL. Potential of Essential Oil-Based Anticholinesterase Insecticides against Anopheles Vectors: A Review. Molecules. 2022 Oct 18; 27(20). PMID: 36296618; PMCID: PMC9611659.
      Citations: 2     Fields:    Translation:HumansAnimalsPHPublic Health
    8. Bashar MA, Miot J, Shoul E, van Zyl RL. Impact of an antibiotic stewardship programme in a surgical setting. S Afr J Infect Dis. 2021; 36(1):307. PMID: 34917678; PMCID: PMC8661296.
      Citations: 8     
    9. Augie BM, van Zyl RL, McInerney PA, Miot J. Knowledge and perceptions about antibiotic resistance and prudent antibiotic prescribing among final year medical students in two African countries. Int J Pharm Pract. 2021 Oct 18; 29(5):508-514. PMID: 34331444.
      Citations: 6     Fields:    Translation:Humans
    10. Rants'o TA, Johan van der Westhuizen C, van Zyl RL. Optimization of covalent docking for organophosphates interaction with Anopheles acetylcholinesterase. J Mol Graph Model. 2022 01; 110:108054. PMID: 34688161.
      Citations: 6     Fields:    Translation:AnimalsCellsPHPublic Health
    11. Augie BM, Miot J, van Zyl RL, McInerney PA. Educational antimicrobial stewardship programs in medical schools: a scoping review. JBI Evid Synth. 2021 08 13; 19(11):2906-2928. PMID: 34392265.
      Citations: 1     Fields:    Translation:Humans
    12. Kayamba F, Malimabe T, Ademola IK, Pooe OJ, Kushwaha ND, Mahlalela M, van Zyl RL, Gordon M, Mudau PT, Zininga T, Shonhai A, Nyamori VO, Karpoormath R. Design and synthesis of quinoline-pyrimidine inspired hybrids as potential plasmodial inhibitors. Eur J Med Chem. 2021 May 05; 217:113330. PMID: 33744688.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    13. Govender S, Pfister C, Rayner B, Dyer R, Flint M, Roodt F, Davids J, Nejthardt MB, Swanevelder JL, Chiu E, Cloete E, Koller V, Pretorius T, Fullerton Z, Roos J, Van Zyl R, Biccard BM. A multicentre cross-sectional descriptive study evaluating the cardiovascular risk profile of preoperatively identified patients with hypertension. S Afr Med J. 2020 Dec 14; 111(1):74-79. PMID: 33404010.
      Citations: 1     Fields:    Translation:HumansPHPublic Health
    14. Augie BM, McInerney PA, van Zyl RL, Miot J. Educational antimicrobial stewardship programs in medical schools: a scoping review protocol. JBI Evid Synth. 2020 05; 18(5):1028-1035. PMID: 32813355.
      Citations:    Fields:    Translation:Humans
    15. Mathebula B, Butsi KR, van Zyl RL, Jansen van Vuuren NC, Hoppe HC, Michael JP, de Koning CB, Rousseau AL. Preparation and antiplasmodial activity of 3',4'-dihydro-1'H-spiro(indoline-3,2'-quinolin)-2-ones. Chem Biol Drug Des. 2019 10; 94(4):1849-1858. PMID: 31361393.
      Citations: 2     Fields:    Translation:HumansAnimals
    16. Dlamini N, Mukaya HE, Van Zyl RL, Chen CT, Zeevaart RJ, Mbianda XY. Synthesis, characterization, kinetic drug release and anticancer activity of bisphosphonates multi-walled carbon nanotube conjugates. Mater Sci Eng C Mater Biol Appl. 2019 Nov; 104:109967. PMID: 31499981.
      Citations: 4     Fields:    Translation:HumansCells
    17. Munedzimwe TC, van Zyl RL, Heslop DC, Edkins AL, Beukes DR. Semi-Synthesis and Evaluation of Sargahydroquinoic Acid Derivatives as Potential Antimalarial Agents. Medicines (Basel). 2019 Apr 01; 6(2). PMID: 30939856; PMCID: PMC6630221.
      Citations: 2     
    18. Dlamini NL, Mukaya HE, Van Zyl RL, Jansen van Vuuren NC, Mbianda XY. Carbon nanospheres conjugated bisphosphonates: synthesis, characterization and in vitro antimalarial activity. Artif Cells Nanomed Biotechnol. 2018; 46(sup3):S287-S296. PMID: 30648446.
      Citations: 2     Fields:    Translation:HumansAnimals
    19. Ansari MF, Hayat F, Inam A, Kathrada F, van Zyl RL, Coetzee M, Ahmad K, Shin D, Azam A. New antiprotozoal agents: Synthesis and biological evaluation of different 4-(7-chloroquinolin-4-yl) piperazin-1-yl)pyrrolidin-2-yl)methanone derivatives. Bioorg Med Chem Lett. 2017 02 01; 27(3):460-465. PMID: 28027871.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    20. Lourens AC, Gravestock D, van Zyl RL, Hoppe HC, Kolesnikova N, Taweechai S, Yuthavong Y, Kamchonwongpaisan S, Rousseau AL. Design, synthesis and biological evaluation of 6-aryl-1,6-dihydro-1,3,5-triazine-2,4-diamines as antiplasmodial antifolates. Org Biomol Chem. 2016 Aug 16; 14(33):7899-911. PMID: 27477595.
      Citations: 4     Fields:    Translation:AnimalsCells
    21. Knight M, van Zyl RL, Sanne I, Bassett J, van Rie A. Impact of combination antiretroviral therapy initiation on adherence to antituberculosis treatment. South Afr J HIV Med. 2015; 16(1):346. PMID: 29568579; PMCID: PMC5850563.
      Citations: 2     
    22. Naidoo D, van Vuuren SF, van Zyl RL, de Wet H. Plants traditionally used individually and in combination to treat sexually transmitted infections in northern Maputaland, South Africa: antimicrobial activity and cytotoxicity. J Ethnopharmacol. 2013 Oct 07; 149(3):656-67. PMID: 23880127.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    23. Salahuddin A, Inam A, van Zyl RL, Heslop DC, Chen CT, Avecilla F, Agarwal SM, Azam A. Synthesis and evaluation of 7-chloro-4-(piperazin-1-yl)quinoline-sulfonamide as hybrid antiprotozoal agents. Bioorg Med Chem. 2013 Jun 01; 21(11):3080-9. PMID: 23602620.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    24. Hayat F, Moseley E, Salahuddin A, Van Zyl RL, Azam A. Antiprotozoal activity of chloroquinoline based chalcones. Eur J Med Chem. 2011 May; 46(5):1897-905. PMID: 21377771.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    25. Gravestock D, Rousseau AL, Lourens AC, Moleele SS, van Zyl RL, Steenkamp PA. Expeditious synthesis and biological evaluation of novel 2,N6-disubstituted 1,2-dihydro-1,3,5-triazine-4,6-diamines as potential antimalarials. Eur J Med Chem. 2011 Jun; 46(6):2022-30. PMID: 21420762.
      Citations:    Fields:    Translation:AnimalsCells
    26. Sibandze GF, van Zyl RL, van Vuuren SF. The anti-diarrhoeal properties of Breonadia salicina, Syzygium cordatum and Ozoroa sphaerocarpa when used in combination in Swazi traditional medicine. J Ethnopharmacol. 2010 Nov 11; 132(2):506-11. PMID: 20817084.
      Citations: 11     Fields:    Translation:AnimalsCells
    27. De Villiers BJ, Van Vuuren SF, Van Zyl RL, Van Wyk BE. Antimicrobial and antimalarial activity of Cussonia species (Araliaceae). J Ethnopharmacol. 2010 May 27; 129(2):189-96. PMID: 20298772.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    28. Nyiligira E, Viljoen AM, Van Heerden FR, Van Zyl RL, Van Vuuren SF, Steenkamp PA. Phytochemistry and in vitro pharmacological activities of South African Vitex (Verbenaceae) species. J Ethnopharmacol. 2008 Oct 28; 119(3):680-5. PMID: 18678237.
      Citations: 8     Fields:    Translation:AnimalsCells
    29. Paraskeva MP, van Vuuren SF, van Zyl RL, Davids H, Viljoen AM. The in vitro biological activity of selected South African Commiphora species. J Ethnopharmacol. 2008 Oct 28; 119(3):673-9. PMID: 18640253.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    30. Essop AB, van Zyl RL, van Vuuren SF, Mulholland D, Viljoen AM. The in vitro pharmacological activities of 12 South African Hermannia species. J Ethnopharmacol. 2008 Oct 28; 119(3):615-9. PMID: 18640257.
      Citations:    Fields:    Translation:HumansAnimalsCells
    31. Bhat AR, Athar F, Van Zyl RL, Chen CT, Azam A. Synthesis and biological evaluation of novel 4-substituted 1-{[4-(10,15,20-triphenylporphyrin-5-yl)phenyl]methylidene}thiosemicarbazides as new class of potential antiprotozoal agents. Chem Biodivers. 2008 May; 5(5):764-76. PMID: 18493963.
      Citations: 5     Fields:    Translation:AnimalsCells
    32. De Wet H, Van Heerden FR, Van Wyk BE, Van Zyl RL. Antiplasmodial activity and cytotoxicity of Albertisia delagoensis. Fitoterapia. 2007 Sep; 78(6):420-2. PMID: 17570613.
      Citations: 1     Fields:    Translation:Animals
    33. Chemaly SM, Chen CT, van Zyl RL. Naturally occurring cobalamins have antimalarial activity. J Inorg Biochem. 2007 May; 101(5):764-73. PMID: 17343914.
      Citations: 3     Fields:    Translation:HumansAnimals
    34. Kamatou GP, Viljoen AM, Gono-Bwalya AB, van Zyl RL, van Vuuren SF, Lourens AC, Baser KH, Demirci B, Lindsey KL, van Staden J, Steenkamp P. The in vitro pharmacological activities and a chemical investigation of three South African Salvia species. J Ethnopharmacol. 2005 Dec 01; 102(3):382-90. PMID: 16099614.
      Citations: 22     Fields:    Translation:Animals
    35. Uys AC, Malan SF, van Dyk S, van Zyl RL. Antimalarial compounds from Parinari capensis. Bioorg Med Chem Lett. 2002 Aug 19; 12(16):2167-9. PMID: 12127529.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    36. Harmse L, van Zyl R, Gray N, Schultz P, Leclerc S, Meijer L, Doerig C, Havlik I. Structure-activity relationships and inhibitory effects of various purine derivatives on the in vitro growth of Plasmodium falciparum. Biochem Pharmacol. 2001 Aug 01; 62(3):341-8. PMID: 11434907.
      Citations: 12     Fields:    Translation:Animals
    37. van Zyl RL, Havlik I, Hempelmann E, MacPhail AP, McNamara L. Malaria pigment and extracellular iron. Possible target for iron chelating agents. Biochem Pharmacol. 1993 Apr 06; 45(7):1431-6. PMID: 8471067.
      Citations:    Fields:    Translation:AnimalsCells
    38. van Zyl RL, Havlik I, Monteagudo FS. The combined effect of iron chelators and classical antimalarials on the in-vitro growth of Plasmodium falciparum. J Antimicrob Chemother. 1992 Sep; 30(3):273-8. PMID: 1452491.
      Citations: 4     Fields:    Translation:Animals
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