Nucleic Acid Hybridization
"Nucleic Acid Hybridization" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Widely used technique which exploits the ability of complementary sequences in single-stranded DNAs or RNAs to pair with each other to form a double helix. Hybridization can take place between two complimentary DNA sequences, between a single-stranded DNA and a complementary RNA, or between two RNA sequences. The technique is used to detect and isolate specific sequences, measure homology, or define other characteristics of one or both strands. (Kendrew, Encyclopedia of Molecular Biology, 1994, p503)
Descriptor ID |
D009693
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MeSH Number(s) |
E05.393.661 G02.111.611
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Concept/Terms |
Nucleic Acid Hybridization- Nucleic Acid Hybridization
- Acid Hybridization, Nucleic
- Acid Hybridizations, Nucleic
- Hybridization, Nucleic Acid
- Hybridizations, Nucleic Acid
- Nucleic Acid Hybridizations
Genomic Hybridization- Genomic Hybridization
- Genomic Hybridizations
- Hybridization, Genomic
- Hybridizations, Genomic
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Below are MeSH descriptors whose meaning is more general than "Nucleic Acid Hybridization".
Below are MeSH descriptors whose meaning is more specific than "Nucleic Acid Hybridization".
This graph shows the total number of publications written about "Nucleic Acid Hybridization" by people in this website by year, and whether "Nucleic Acid Hybridization" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2000 | 0 | 1 | 1 |
2003 | 1 | 0 | 1 |
2010 | 1 | 0 | 1 |
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Below are the most recent publications written about "Nucleic Acid Hybridization" by people in Profiles.
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A comparison of DNA sequencing and the hydrolysis probe analysis (TaqMan assay) for knockdown resistance (kdr) mutations in Anopheles gambiae from the Republic of the Congo. Malar J. 2010 Oct 12; 9:278.
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Frequent coinfection with hepatitis B virus strains of distinct genotypes detected by hybridization with type-specific probes immobilized on a solid-phase support. J Virol Methods. 2003 Jun 09; 110(1):29-35.
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Use of PCR to detect Leishmania (Viannia) spp. in dog blood and bone marrow. J Clin Microbiol. 2000 Feb; 38(2):748-51.
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Inhibition of primer extension by single mismatches during asymmetric re-amplification. Biochem J. 1992 Dec 15; 288 ( Pt 3):1073-4.