"Hydrochlorothiazide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
| Descriptor ID |
D006852
|
| MeSH Number(s) |
D02.886.590.700.135.261.476 D02.886.655.500.261.476 D03.633.100.174.261.476
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Hydrochlorothiazide".
Below are MeSH descriptors whose meaning is more specific than "Hydrochlorothiazide".
This graph shows the total number of publications written about "Hydrochlorothiazide" by people in this website by year, and whether "Hydrochlorothiazide" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
| 2002 | 1 | 1 | 2 |
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Below are the most recent publications written about "Hydrochlorothiazide" by people in Profiles.
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Comparison of indapamide and low-dose hydrochlorothiazide monotherapy in black patients with mild to moderate hypertension. S Afr Med J. 2002 Jul; 92(7):532-6.
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Relationship between treatment-induced changes in left ventricular mass and blood pressure in black african hypertensive patients: results of the Baragwanath Trial. Circulation. 2002 Feb 19; 105(7):830-6.
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Efficacy of different drug classes used to initiate antihypertensive treatment in black subjects: results of a randomized trial in Johannesburg, South Africa. Arch Intern Med. 2001 Apr 09; 161(7):965-71.
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Antihypertensive effect of low-dose hydrochlorothiazide alone or in combination with quinapril in black patients with mild to moderate hypertension. J Clin Pharmacol. 2000 Jul; 40(7):713-21.
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Comparison of acebutolol with and without hydrochlorothiazide versus carvedilol with and without hydrochlorothiazide in black patients with mild to moderate systemic hypertension. Am J Cardiol. 1999 Jul 01; 84(1):70-5.
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Hydrochlorothiazide improves ventricular compliance and thus performance without reducing hypertrophy in renal artery stenosis in rats. Hypertension. 1993 May; 21(5):638-45.
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A double-blind trial in hypertension comparing Baycaron (FBA 1500), hydrochlorothiazide and placebo. S Afr Med J. 1971 Mar 20; 45(12):323.