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Geoffrey

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Elebo N, Abdel-Shafy EA, Omoshoro-Jones JAO, Nsingwane Z, Hussein AAA, Smith M, Candy G, Cacciatore S, Fru P, Nweke EE. Comparative immune profiling of pancreatic ductal adenocarcinoma progression among South African patients. BMC Cancer. 2024 Jul 07; 24(1):809. PMID: 38973003; PMCID: PMC11229237.
      Citations:    Fields:    Translation:HumansCells
    2. Baichan P, Naicker P, Augustine TN, Smith M, Candy G, Devar J, Nweke EE. Proteomic analysis identifies dysregulated proteins and associated molecular pathways in a cohort of gallbladder cancer patients of African ancestry. Clin Proteomics. 2023 Mar 01; 20(1):8. PMID: 36855072; PMCID: PMC9976386.
      Citations: 1     
    3. Grossberg SJ, Brener JD, Bizos EL, Candy GP, Bizos DB. The negative appendicectomy rate at Charlotte Maxeke Johannesburg Academic Hospital - a 10-year review. S Afr J Surg. 2022 Mar; 60(1):4-9. PMID: 35451262.
      Citations:    Fields:    Translation:Humans
    4. Elebo N, Omoshoro-Jones J, Fru PN, Devar J, De Wet van Zyl C, Vorster BC, Smith M, Cacciatore S, Zerbini LF, Candy G, Nweke EE. Serum Metabolomic and Lipoprotein Profiling of Pancreatic Ductal Adenocarcinoma Patients of African Ancestry. Metabolites. 2021 Sep 28; 11(10). PMID: 34677378; PMCID: PMC8540259.
      Citations: 8     
    5. Xelwa N, Candy GP, Devar J, Omoshoro-Jones J, Smith M, Nweke EE. Targeting Growth Factor Signaling Pathways in Pancreatic Cancer: Towards Inhibiting Chemoresistance. Front Oncol. 2021; 11:683788. PMID: 34195085; PMCID: PMC8236623.
      Citations: 4     
    6. Augustine TN, Duarte R, Candy GP. Breast Cancer Cells Induce a Pro-inflammatory Response to Mitigate Immune Mediation in a 3D Culture Model. Anticancer Res. 2020 Nov; 40(11):6179-6193. PMID: 33109555.
      Citations: 1     Fields:    Translation:HumansCells
    7. Nweke EE, Naicker P, Aron S, Stoychev S, Devar J, Tabb DL, Omoshoro-Jones J, Smith M, Candy G. SWATH-MS based proteomic profiling of pancreatic ductal adenocarcinoma tumours reveals the interplay between the extracellular matrix and related intracellular pathways. PLoS One. 2020; 15(10):e0240453. PMID: 33048956; PMCID: PMC7553299.
      Citations: 8     Fields:    Translation:HumansCells
    8. Nsingwane Z, Candy G, Devar J, Omoshoro-Jones J, Smith M, Nweke E. Immunotherapeutic strategies in pancreatic ductal adenocarcinoma (PDAC): current perspectives and future prospects. Mol Biol Rep. 2020 Aug; 47(8):6269-6280. PMID: 32661873.
      Citations: 4     Fields:    Translation:HumansAnimals
    9. Mannell A, Nel CE, Smilg JS, Haberfield J, Nietz S, Candy GP. A prospective study of receptor profiles in breast cancer and the ipsilateral axillary lymph node metastases measured simultaneously in treatment naïve cases. S Afr J Surg. 2020 Jun; 58(2):86-90. PMID: 32644312.
      Citations: 2     Fields:    Translation:Humans
    10. Nweke E, Ntwasa M, Brand M, Devar J, Smith M, Candy G. Increased expression of plakoglobin is associated with upregulated MAPK and PI3K/AKT signalling pathways in early resectable pancreatic ductal adenocarcinoma. Oncol Lett. 2020 Jun; 19(6):4133-4141. PMID: 32382352; PMCID: PMC7202312.
      Citations: 6     
    11. Baichan P, Naicker P, Devar JWS, Smith M, Candy GP, Nweke E. Targeting gallbladder cancer: a pathway based perspective. Mol Biol Rep. 2020 Mar; 47(3):2361-2369. PMID: 32020429.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    12. Thomson JE, Nweke EE, Brand M, Nel M, Candy GP, Fonteh PN. Transient Expression of Interleukin-21 in the Second Hit of Acute Pancreatitis May Potentiate Immune Paresis in Severe Acute Pancreatitis. Pancreas. 2019 01; 48(1):107-112. PMID: 30451792.
      Citations: 6     Fields:    Translation:Humans
    13. Tsai MC, Candy G, Costello MA, Grieve AD, Brand M. Do iatrogenic serosal injuries result in small bowel perforation in a rabbit model? S Afr J Surg. 2017 Jun; 55(2):18-22. PMID: 28876619.
      Citations:    Fields:    Translation:Animals
    14. Spencer K, Haffejee M, Candy G, Kaseke E. Intimate partner violence at a tertiary institution. S Afr Med J. 2016 Nov 02; 106(11):1129-1133. PMID: 27842637.
      Citations: 1     Fields:    
    15. Smerup M, Damkjær M, Brøndum E, Baandrup UT, Kristiansen SB, Nygaard H, Funder J, Aalkjær C, Sauer C, Buchanan R, Bertelsen MF, Østergaard K, Grøndahl C, Candy G, Hasenkam JM, Secher NH, Bie P, Wang T. The thick left ventricular wall of the giraffe heart normalises wall tension, but limits stroke volume and cardiac output. J Exp Biol. 2016 Feb; 219(Pt 3):457-63. PMID: 26643090.
      Citations: 8     Fields:    Translation:Animals
    16. Augustine TN, Dix-Peek T, Duarte R, Candy GP. Establishment of a heterotypic 3D culture system to evaluate the interaction of TREG lymphocytes and NK cells with breast cancer. J Immunol Methods. 2015 Nov; 426:1-13. PMID: 26215372.
      Citations: 17     Fields:    Translation:HumansCells
    17. Seape T, Gounden V, van Deventer HE, Candy GP, George JA. Cystatin C- and creatinine-based equations in the assessment of renal function in HIV-positive patients prior to commencing Highly Active Antiretroviral Therapy. Ann Clin Biochem. 2016 Jan; 53(Pt 1):58-66. PMID: 25766385.
      Citations: 22     Fields:    Translation:Humans
    18. Fockema MW, Candy GP, Kruger D, Haffejee M. Enuresis in South African children: prevalence, associated factors and parental perception of treatment. BJU Int. 2012 Dec; 110(11 Pt C):E1114-20. PMID: 22958477.
      Citations: 10     Fields:    Translation:Humans
    19. Libhaber EN, Norton GR, Libhaber CD, Woodiwiss AJ, Candy GP, Essop MR, Sareli P. Prevalence of residual left ventricular structural changes after one year of antihypertensive treatment in patients of African descent: role of 24-hour pulse pressure. Cardiovasc J Afr. 2012 Apr; 23(3):147-52. PMID: 22354147; PMCID: PMC3721865.
      Citations: 2     Fields:    Translation:Humans
    20. Nel MJ, Woodiwiss AJ, Candy GP. Modeling of cellular arginine uptake by more than one transporter. J Membr Biol. 2012 Jan; 245(1):1-13. PMID: 22113524.
      Citations: 2     Fields:    Translation:HumansCells
    21. Widgerow AD, Chait LA, Stals PJ, Stals R, Candy G. Multimodality scar management program. Aesthetic Plast Surg. 2009 Jul; 33(4):533-43. PMID: 19048338.
      Citations: 11     Fields:    Translation:Humans
    22. Pillai J, Levien LJ, Haagensen M, Candy G, Cluver MD, Veller MG. Assessment of the medial head of the gastrocnemius muscle in functional compression of the popliteal artery. J Vasc Surg. 2008 Nov; 48(5):1189-96. PMID: 18971035.
      Citations: 8     Fields:    Translation:Humans
    23. Hähnle UR, Sliwa K, de Villiers M, Weinberg IR, Sweet BM, Candy GP. Is Degenerative Spondylolisthesis a Contraindication for Total Disc Replacement? Kineflex Lumbar Disc Replacement in 7 Patients With 24-Month Follow-up. SAS J. 2008; 2(2):92-100. PMID: 25802608; PMCID: PMC4365827.
      Citations:    
    24. Widgerow AD, Wittstock C, Candy GP. Lavage drain extension for local anaesthetic instillation into abdominal wounds. S Afr J Surg. 2008 Feb; 46(1):14-6. PMID: 18468417.
      Citations: 1     Fields:    Translation:Humans
    25. Pillai J, Britz R, Cluver MD, Candy GP, Abdool-Carrim AT, Veller MG. Proximal suture line support in open abdominal aortic aneurysm repair: a comparative study. Eur J Vasc Endovasc Surg. 2008 Mar; 35(3):301-5. PMID: 17988906.
      Citations:    Fields:    Translation:Humans
    26. Hähnle UR, Sliwa K, Weinberg IR, Sweet BM, de Villiers M, Candy GP. Lumbar disc replacement for junctional decompensation after fusion surgery: clinical and radiological outcome at an average follow-up of 33 months. SAS J. 2007; 1(3):85-92. PMID: 25802584; PMCID: PMC4365576.
      Citations:    
    27. Wong ML, Back P, Candy G, Nelson G, Murray J. Cryptococcal pneumonia in African miners at autopsy. Int J Tuberc Lung Dis. 2007 May; 11(5):528-33. PMID: 17439676.
      Citations: 8     Fields:    Translation:Humans
    28. Wong ML, Back P, Candy G, Nelson G, Murray J. Pneumocystis jirovecii pneumonia in African miners at autopsy. Int J Tuberc Lung Dis. 2006 Jul; 10(7):756-60. PMID: 16848337.
      Citations: 7     Fields:    Translation:HumansAnimals
    29. Woodiwiss AJ, Nkeh B, Samani NJ, Badenhorst D, Maseko M, Tiago AD, Candy GP, Libhaber E, Sareli P, Brooksbank R, Norton GR. Functional variants of the angiotensinogen gene determine antihypertensive responses to angiotensin-converting enzyme inhibitors in subjects of African origin. J Hypertens. 2006 Jun; 24(6):1057-64. PMID: 16685205.
      Citations: 6     Fields:    Translation:Humans
    30. Libhaber EN, Norton GR, Libhaber CD, Candy GP, Woodiwiss AJ, Sliwa K, Essop MR, Sareli P. Change in blood pressure predicts regression of cardiac hypertrophy in patients of African ancestry receiving agents influencing the renin-angiotensin system. J Hum Hypertens. 2005 Aug; 19(8):659-61. PMID: 15905887.
      Citations:    Fields:    Translation:Humans
    31. Sliwa K, Norton GR, Kone N, Candy G, Kachope J, Woodiwiss AJ, Libhaber C, Sareli P, Essop R. Impact of initiating carvedilol before angiotensin-converting enzyme inhibitor therapy on cardiac function in newly diagnosed heart failure. J Am Coll Cardiol. 2004 Nov 02; 44(9):1825-30. PMID: 15519014.
      Citations: 16     Fields:    Translation:HumansCTClinical Trials
    32. Sliwa K, Forster O, Zhanje F, Candy G, Kachope J, Essop R. Outcome of subsequent pregnancy in patients with documented peripartum cardiomyopathy. Am J Cardiol. 2004 Jun 01; 93(11):1441-3, A10. PMID: 15165937.
      Citations: 15     Fields:    Translation:Humans
    33. Libhaber EN, Libhaber CD, Candy GP, Sliwa K, Kachope J, Hlatshwayo NM, Puane MO, Woodiwiss AJ, Norton GR, Essop MR, Sareli P. Effect of slow-release indapamide and perindopril compared with amlodipine on 24-hour blood pressure and left ventricular mass in hypertensive patients of African ancestry. Am J Hypertens. 2004 May; 17(5 Pt 1):428-32. PMID: 15110902.
      Citations: 3     Fields:    Translation:HumansCTClinical Trials
    34. Sliwa K, Woodiwiss A, Kone VN, Candy G, Badenhorst D, Norton G, Zambakides C, Peters F, Essop R. Therapy of ischemic cardiomyopathy with the immunomodulating agent pentoxifylline: results of a randomized study. Circulation. 2004 Feb 17; 109(6):750-5. PMID: 14970111.
      Citations: 40     Fields:    Translation:HumansCTClinical Trials
    35. Tiago AD, Badenhorst D, Nkeh B, Candy GP, Brooksbank R, Sareli P, Libhaber E, Samani NJ, Woodiwiss AJ, Norton GR. Impact of renin-angiotensin-aldosterone system gene variants on the severity of hypertension in patients with newly diagnosed hypertension. Am J Hypertens. 2003 Dec; 16(12):1006-10. PMID: 14643573.
      Citations: 10     Fields:    Translation:Humans
    36. Sliwa K, Woodiwiss A, Candy G, Badenhorst D, Libhaber C, Norton G, Skudicky D, Sareli P. Effects of pentoxifylline on cytokine profiles and left ventricular performance in patients with decompensated congestive heart failure secondary to idiopathic dilated cardiomyopathy. Am J Cardiol. 2002 Nov 15; 90(10):1118-22. PMID: 12423714.
      Citations: 35     Fields:    Translation:HumansCTClinical Trials
    37. Tiago AD, Samani NJ, Candy GP, Brooksbank R, Libhaber EN, Sareli P, Woodiwiss AJ, Norton GR. Angiotensinogen gene promoter region variant modifies body size-ambulatory blood pressure relations in hypertension. Circulation. 2002 Sep 17; 106(12):1483-7. PMID: 12234952.
      Citations: 11     Fields:    Translation:HumansCells
    38. Radevski IV, Valtchanova ZP, Candy GP, Wald AM, Ngcezula T, Sareli P. Comparison of indapamide and low-dose hydrochlorothiazide monotherapy in black patients with mild to moderate hypertension. S Afr Med J. 2002 Jul; 92(7):532-6. PMID: 12197195.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    39. Tiago AD, Badenhorst D, Skudicky D, Woodiwiss AJ, Candy GP, Brooksbank R, Sliwa K, Sareli P, Norton GR. An aldosterone synthase gene variant is associated with improvement in left ventricular ejection fraction in dilated cardiomyopathy. Cardiovasc Res. 2002 Jun; 54(3):584-9. PMID: 12031704.
      Citations: 15     Fields:    Translation:Humans
    40. Sliwa K, Skudicky D, Candy G, Bergemann A, Hopley M, Sareli P. The addition of pentoxifylline to conventional therapy improves outcome in patients with peripartum cardiomyopathy. Eur J Heart Fail. 2002 Jun; 4(3):305-9. PMID: 12034156.
      Citations: 40     Fields:    Translation:HumansCTClinical Trials
    41. Nkeh B, Tiago A, Candy GP, Woodiwiss AJ, Badenhorst D, Luker F, Netjhardt M, Brooksbank R, Libhaber C, Sareli P, Norton GR. Association between an atrial natriuretic peptide gene polymorphism and normal blood pressure in subjects of African ancestry. Cardiovasc J S Afr. 2002 May-Jun; 13(3):97-101. PMID: 12193960.
      Citations: 7     Fields:    Translation:Humans
    42. Skudicky D, Sareli P, Libhaber E, Candy G, Radevski I, Valtchanova Z, Tshele E, Thijs L, Wang JG, Staessen JA. Relationship between treatment-induced changes in left ventricular mass and blood pressure in black african hypertensive patients: results of the Baragwanath Trial. Circulation. 2002 Feb 19; 105(7):830-6. PMID: 11854123.
      Citations: 5     Fields:    Translation:HumansCTClinical Trials
    43. Sareli P, Radevski IV, Valtchanova ZP, Libhaber E, Candy GP, Den Hond E, Libhaber C, Skudicky D, Wang JG, Staessen JA. Efficacy of different drug classes used to initiate antihypertensive treatment in black subjects: results of a randomized trial in Johannesburg, South Africa. Arch Intern Med. 2001 Apr 09; 161(7):965-71. PMID: 11295959.
      Citations: 15     Fields:    Translation:HumansCTClinical Trials
    44. Tiago AD, Nkeh B, Candy GP, Badenhorst D, Defterios D, Brooksbank R, Nejthardt M, Luker F, Milne J, Woodiwiss AJ, Norton GR. Association study of eight candidate genes with renin status in mild-to-moderate hypertension in patients of African ancestry. Cardiovasc J S Afr. 2001 Apr-May; 12(2):75-80. PMID: 11447495.
      Citations: 3     Fields:    Translation:Humans
    45. Skudicky D, Bergemann A, Sliwa K, Candy G, Sareli P. Beneficial effects of pentoxifylline in patients with idiopathic dilated cardiomyopathy treated with angiotensin-converting enzyme inhibitors and carvedilol: results of a randomized study. Circulation. 2001 Feb 27; 103(8):1083-8. PMID: 11222470.
      Citations: 40     Fields:    Translation:HumansCTClinical Trials
    46. Skudicky D, Sliwa K, Bergemann A, Candy G, Sareli P. Reduction in Fas/APO-1 plasma concentrations correlates with improvement in left ventricular function in patients with idiopathic dilated cardiomyopathy treated with pentoxifylline. Heart. 2000 Oct; 84(4):438-9. PMID: 10995419; PMCID: PMC1729442.
      Citations: 15     Fields:    Translation:HumansCTClinical Trials
    47. Radevski IV, Valtchanova ZP, Candy GP, Hlatswayo MN, Sareli P. Antihypertensive effect of low-dose hydrochlorothiazide alone or in combination with quinapril in black patients with mild to moderate hypertension. J Clin Pharmacol. 2000 Jul; 40(7):713-21. PMID: 10883412.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    48. Sliwa K, Skudicky D, Bergemann A, Candy G, Puren A, Sareli P. Peripartum cardiomyopathy: analysis of clinical outcome, left ventricular function, plasma levels of cytokines and Fas/APO-1. J Am Coll Cardiol. 2000 Mar 01; 35(3):701-5. PMID: 10716473.
      Citations: 69     Fields:    Translation:Humans
    49. Candy G, Samani N, Norton G, Woodiwiss A, Radevski I, Wheatley A, Cockcroft J, Hall IP. Association analysis of beta2 adrenoceptor polymorphisms with hypertension in a Black African population. J Hypertens. 2000 Feb; 18(2):167-72. PMID: 10694184.
      Citations: 11     Fields:    Translation:HumansCells
    50. Radevski IV, Valtchanova SP, Candy GP, Tshele EF, Sareli P. Comparison of acebutolol with and without hydrochlorothiazide versus carvedilol with and without hydrochlorothiazide in black patients with mild to moderate systemic hypertension. Am J Cardiol. 1999 Jul 01; 84(1):70-5. PMID: 10404854.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    51. Candy GP, Skudicky D, Mueller UK, Woodiwiss AJ, Sliwa K, Luker F, Esser J, Sareli P, Norton GR. Association of left ventricular systolic performance and cavity size with angiotensin-converting enzyme genotype in idiopathic dilated cardiomyopathy. Am J Cardiol. 1999 Mar 01; 83(5):740-4. PMID: 10080429.
      Citations: 13     Fields:    Translation:Humans
    52. Radevski I, Skudicky D, Candy G, Sathekge S, Strugo V, Sareli P. Antihypertensive monotherapy with nisoldipine CC is superior to enalapril in black patients with severe hypertension. Am J Hypertens. 1999 Feb; 12(2 Pt 1):194-203. PMID: 10090348.
      Citations: 13     Fields:    Translation:HumansCTClinical Trials
    53. Sliwa K, Skudicky D, Candy G, Wisenbaugh T, Sareli P. Randomised investigation of effects of pentoxifylline on left-ventricular performance in idiopathic dilated cardiomyopathy. Lancet. 1998 Apr 11; 351(9109):1091-3. PMID: 9660578.
      Citations: 46     Fields:    Translation:HumansCTClinical Trials
    54. Evans JP, Candy GP, Veller MG, Esser JD. A method for creating reversible ureteric obstruction in the primate. J Med Primatol. 1998 Feb; 27(1):44-8. PMID: 9606043.
      Citations:    Fields:    Translation:Animals
    55. Norton GR, Tsotetsi J, Trifunovic B, Hartford C, Candy GP, Woodiwiss AJ. Myocardial stiffness is attributed to alterations in cross-linked collagen rather than total collagen or phenotypes in spontaneously hypertensive rats. Circulation. 1997 Sep 16; 96(6):1991-8. PMID: 9323091.
      Citations: 52     Fields:    Translation:Animals
    56. Evans JP, Candy GP, Veller MG, Esser JD. The glomerular filtration rate, effective renal plasma flow, and renal blood flow in the adult male chacma baboon (Papio ursinus). J Med Primatol. 1996 Dec; 25(6):382-6. PMID: 9210022.
      Citations:    Fields:    Translation:HumansAnimals
    57. Norton GR, Candy G, Woodiwiss AJ. Aminoguanidine prevents the decreased myocardial compliance produced by streptozotocin-induced diabetes mellitus in rats. Circulation. 1996 May 15; 93(10):1905-12. PMID: 8635270.
      Citations: 59     Fields:    Translation:Animals
    58. Fine DR, Lurie RE, Candy GP. An anatomical and physiological model of the renal parenchyma--model development and parametric identification. Physiol Meas. 1994 Nov; 15(4):407-28. PMID: 7881364.
      Citations: 2     Fields:    Translation:Humans
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