"beta 2-Microglobulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An 11-kDa protein associated with the outer membrane of many cells including lymphocytes. It is the small subunit of the MHC class I molecule. Association with beta 2-microglobulin is generally required for the transport of class I heavy chains from the endoplasmic reticulum to the cell surface. Beta 2-microglobulin is present in small amounts in serum, csf, and urine of normal people, and to a much greater degree in the urine and plasma of patients with tubular proteinemia, renal failure, or kidney transplants.
| Descriptor ID |
D001613
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| MeSH Number(s) |
D12.776.124.790.223.100 D12.776.377.715.182.100
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "beta 2-Microglobulin".
Below are MeSH descriptors whose meaning is more specific than "beta 2-Microglobulin".
This graph shows the total number of publications written about "beta 2-Microglobulin" by people in this website by year, and whether "beta 2-Microglobulin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
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Below are the most recent publications written about "beta 2-Microglobulin" by people in Profiles.
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In vivo effects of HIV-1 exposure in the presence and absence of single-dose nevirapine on cellular plasma activation markers of infants born to HIV-1-seropositive mothers. J Acquir Immune Defic Syndr. 2006 Aug 15; 42(5):545-53.
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High human immunodeficiency virus type 1 RNA load in the cerebrospinal fluid from patients with lymphocytic meningitis. J Infect Dis. 1998 Feb; 177(2):473-6.