"Angiotensinogen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An alpha-globulin of about 453 amino acids, depending on the species. It is produced by the liver and secreted into blood circulation. Angiotensinogen is the inactive precursor of natural angiotensins. Upon successive enzyme cleavages, angiotensinogen yields angiotensin I, II, and III with amino acids numbered at 10, 8, and 7, respectively.
| Descriptor ID |
D000808
|
| MeSH Number(s) |
D12.644.456.073.070 D12.644.861.020 D12.776.811.070 D12.776.872.020
|
| Concept/Terms |
Angiotensinogen- Angiotensinogen
- Serpin A8
- Renin-Substrate
- Renin Substrate
- Hypertensinogen
- Proangiotensin
|
Below are MeSH descriptors whose meaning is more general than "Angiotensinogen".
Below are MeSH descriptors whose meaning is more specific than "Angiotensinogen".
This graph shows the total number of publications written about "Angiotensinogen" by people in this website by year, and whether "Angiotensinogen" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 1 | 2 |
| 2003 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Angiotensinogen" by people in Profiles.
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Systemic Angiotensinogen Concentrations Are Independently Associated With Left Ventricular Diastolic Function in a Community Sample. Am J Hypertens. 2018 01 12; 31(2):212-219.
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Urinary angiotensinogen excretion is associated with blood pressure independent of the circulating renin-angiotensin system in a group of african ancestry. Hypertension. 2014 Jul; 64(1):149-56.
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Contribution of circulating angiotensinogen concentrations to variations in aldosterone and blood pressure in a group of African ancestry depends on salt intake. Hypertension. 2012 Jan; 59(1):62-9.
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Gene variants of the renin-angiotensin system and hypertension: from a trough of disillusionment to a welcome phase of enlightenment? Clin Sci (Lond). 2010 Jan 26; 118(8):487-506.
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Functional variants of the angiotensinogen gene determine antihypertensive responses to angiotensin-converting enzyme inhibitors in subjects of African origin. J Hypertens. 2006 Jun; 24(6):1057-64.
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Impact of renin-angiotensin-aldosterone system gene variants on the severity of hypertension in patients with newly diagnosed hypertension. Am J Hypertens. 2003 Dec; 16(12):1006-10.
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Angiotensinogen gene promoter region variant modifies body size-ambulatory blood pressure relations in hypertension. Circulation. 2002 Sep 17; 106(12):1483-7.
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An aldosterone synthase gene variant is associated with improvement in left ventricular ejection fraction in dilated cardiomyopathy. Cardiovasc Res. 2002 Jun; 54(3):584-9.