Transcription Activator-Like Effector Nucleases
"Transcription Activator-Like Effector Nucleases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Artificial nucleases that cleave DNA at a defined distance from specific DNA sequences recognized by TRANSCRIPTION ACTIVATOR-LIKE EFFECTORS. They are composed of an endodeoxyribonuclease fused to DNA-binding domains of the transcription activator-like effectors.
| Descriptor ID |
D000069896
|
| MeSH Number(s) |
D08.811.277.352.335.350.850 D12.776.828.300.850
|
| Concept/Terms |
Transcription Activator-Like Effector Nucleases- Transcription Activator-Like Effector Nucleases
- Transcription Activator Like Effector Nucleases
- Nucleases, Transcription Activator-Like Effector
- Nucleases, Transcription Activator Like Effector
- TALENs
|
Below are MeSH descriptors whose meaning is more general than "Transcription Activator-Like Effector Nucleases".
Below are MeSH descriptors whose meaning is more specific than "Transcription Activator-Like Effector Nucleases".
This graph shows the total number of publications written about "Transcription Activator-Like Effector Nucleases" by people in this website by year, and whether "Transcription Activator-Like Effector Nucleases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Transcription Activator-Like Effector Nucleases" by people in Profiles.
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Improved Specificity and Safety of Anti-Hepatitis B Virus TALENs Using Obligate Heterodimeric FokI Nuclease Domains. Viruses. 2021 07 12; 13(7).
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In vitro transcribed mRNA for expression of designer nucleases: Advantages as a novel therapeutic for the management of chronic HBV infection. Adv Drug Deliv Rev. 2021 01; 168:134-146.
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A T7 Endonuclease I Assay to Detect Talen-Mediated Targeted Mutation of HBV cccDNA. Methods Mol Biol. 2017; 1540:85-95.
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Improved antiviral efficacy using TALEN-mediated homology directed recombination to introduce artificial primary miRNAs into DNA of hepatitis B virus. Biochem Biophys Res Commun. 2016 09 30; 478(4):1563-8.