"fas Receptor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A tumor necrosis factor receptor subtype found in a variety of tissues and on activated LYMPHOCYTES. It has specificity for FAS LIGAND and plays a role in regulation of peripheral immune responses and APOPTOSIS. Multiple isoforms of the protein exist due to multiple ALTERNATIVE SPLICING. The activated receptor signals via a conserved death domain that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM. Mutations in the CD95 gene are associated with cases of autoimmune lymphoproliferative syndrome.
| Descriptor ID |
D019014
|
| MeSH Number(s) |
D12.776.543.750.690.500 D12.776.543.750.705.852.760.195
|
| Concept/Terms |
fas Receptor- fas Receptor
- Receptor, fas
- fas Antigen
- fas Antigens
- APO-1 Antigen
- APO 1 Antigen
- CD95 Antigen
- TNFRSF6 Receptor
- Receptor, TNFRSF6
- Antigens, CD95
- Receptors, fas
- fas Receptors
- Tumor Necrosis Factor Receptor Superfamily, Member 6
- Fas Cell Surface Death Receptor
- CD95 Antigens
|
Below are MeSH descriptors whose meaning is more general than "fas Receptor".
Below are MeSH descriptors whose meaning is more specific than "fas Receptor".
This graph shows the total number of publications written about "fas Receptor" by people in this website by year, and whether "fas Receptor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 2 | 0 | 2 |
| 2001 | 1 | 2 | 3 |
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 2 | 2 |
| 2005 | 1 | 0 | 1 |
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Below are the most recent publications written about "fas Receptor" by people in Profiles.
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Peripartum cardiomyopathy: inflammatory markers as predictors of outcome in 100 prospectively studied patients. Eur Heart J. 2006 Feb; 27(4):441-6.
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C-reactive protein predicts response to pentoxifylline in patients with idiopathic dilated cardiomyopathy. Eur J Heart Fail. 2004 Oct; 6(6):731-4.
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Therapy of ischemic cardiomyopathy with the immunomodulating agent pentoxifylline: results of a randomized study. Circulation. 2004 Feb 17; 109(6):750-5.
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Effects of pentoxifylline on cytokine profiles and left ventricular performance in patients with decompensated congestive heart failure secondary to idiopathic dilated cardiomyopathy. Am J Cardiol. 2002 Nov 15; 90(10):1118-22.
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Expression of Fas antigen (CD95) in peripheral blood lymphocytes and in liver-infiltrating, cytotoxic lymphocytes in patients with hepatocellular carcinoma. Cancer. 2001 Oct 15; 92(8):2136-41.
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A cellular gene up-regulated by hepatitis B virus-encoded X antigen promotes hepatocellular growth and survival. Hepatology. 2001 Jul; 34(1):146-57.
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Beneficial effects of pentoxifylline in patients with idiopathic dilated cardiomyopathy treated with angiotensin-converting enzyme inhibitors and carvedilol: results of a randomized study. Circulation. 2001 Feb 27; 103(8):1083-8.
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Reduction in Fas/APO-1 plasma concentrations correlates with improvement in left ventricular function in patients with idiopathic dilated cardiomyopathy treated with pentoxifylline. Heart. 2000 Oct; 84(4):438-9.
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Peripartum cardiomyopathy: analysis of clinical outcome, left ventricular function, plasma levels of cytokines and Fas/APO-1. J Am Coll Cardiol. 2000 Mar 01; 35(3):701-5.