Systemic Inflammatory Response Syndrome
"Systemic Inflammatory Response Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A systemic inflammatory response to a variety of clinical insults, characterized by two or more of the following conditions: (1) fever >38 degrees C or HYPOTHERMIA <36 degrees C; (2) TACHYCARDIA >90 beat/minute; (3) tachypnea >24 breaths/minute; (4) LEUKOCYTOSIS >12,000 cells/cubic mm or 10% immature forms. While usually related to infection, SIRS can also be associated with noninfectious insults such as TRAUMA; BURNS; or PANCREATITIS. If infection is involved, a patient with SIRS is said to have SEPSIS.
Descriptor ID |
D018746
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MeSH Number(s) |
C23.550.470.790 C23.550.835.900
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Systemic Inflammatory Response Syndrome".
Below are MeSH descriptors whose meaning is more specific than "Systemic Inflammatory Response Syndrome".
- Systemic Inflammatory Response Syndrome
- Sepsis
This graph shows the total number of publications written about "Systemic Inflammatory Response Syndrome" by people in this website by year, and whether "Systemic Inflammatory Response Syndrome" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1997 | 1 | 0 | 1 |
2008 | 0 | 1 | 1 |
2019 | 0 | 1 | 1 |
2021 | 1 | 1 | 2 |
2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Systemic Inflammatory Response Syndrome" by people in Profiles.
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Comparing the immune abnormalities in MIS-C to healthy children and those with inflammatory disease reveals distinct inflammatory cytokine production and a monofunctional T cell response. Clin Immunol. 2024 02; 259:109877.
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Multisystem inflammatory syndrome (MIS): a multicentre retrospective review of adults and adolescents in South Africa. Int J Infect Dis. 2021 Oct; 111:227-232.
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A case of multisystem inflammatory syndrome in an African adolescent male: case report. Pan Afr Med J. 2021; 38:174.
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Transient Expression of Interleukin-21 in the Second Hit of Acute Pancreatitis May Potentiate Immune Paresis in Severe Acute Pancreatitis. Pancreas. 2019 01; 48(1):107-112.
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Infection in obstetric critical care. Best Pract Res Clin Obstet Gynaecol. 2008 Oct; 22(5):865-83.
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Epidemiology of sepsis syndrome in 8 academic medical centers. JAMA. 1997 Jul 16; 278(3):234-40.