"Oligonucleotide Probes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Synthetic or natural oligonucleotides used in hybridization studies in order to identify and study specific nucleic acid fragments, e.g., DNA segments near or within a specific gene locus or gene. The probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the probe include the radioisotope labels 32P and 125I and the chemical label biotin.
| Descriptor ID |
D015345
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| MeSH Number(s) |
D13.444.600.601 D27.505.259.750.600.650 D27.720.470.530.600.650
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| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Oligonucleotide Probes".
Below are MeSH descriptors whose meaning is more specific than "Oligonucleotide Probes".
This graph shows the total number of publications written about "Oligonucleotide Probes" by people in this website by year, and whether "Oligonucleotide Probes" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
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Below are the most recent publications written about "Oligonucleotide Probes" by people in Profiles.
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A comparison of DNA sequencing and the hydrolysis probe analysis (TaqMan assay) for knockdown resistance (kdr) mutations in Anopheles gambiae from the Republic of the Congo. Malar J. 2010 Oct 12; 9:278.
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Evaluation of an oligonucleotide ligation assay for detection of mutations in HIV-1 subtype C individuals who have high level resistance to nucleoside reverse transcriptase inhibitors and non-nucleoside reverse transcriptase inhibitors. J Virol Methods. 2005 May; 125(2):99-109.
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Frequent coinfection with hepatitis B virus strains of distinct genotypes detected by hybridization with type-specific probes immobilized on a solid-phase support. J Virol Methods. 2003 Jun 09; 110(1):29-35.
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Fiber sequence heterogeneity in subgroup F adenoviruses. Virology. 1990 Nov; 179(1):139-50.