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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Dubner J, Neugut AI, Joffe M, O'Neil DS, Ayeni OA, Chen WC, Buccimazza I, Cacala SR, Stopforth LW, Farrow HA, Nietz S, Murugan N, Phakathi B, Jacobson JS, Crew KD, McCormack V, Ruff P, Cubasch H, Pumpalova YS. The association of HIV status with triple-negative breast cancer in patients with breast cancer in South Africa: a cross-sectional analysis of case-only data from a prospective cohort study. Lancet Glob Health. 2024 Dec; 12(12):e1993-e2002. PMID: 39577973; PMCID: PMC11584318.
      Citations:    Fields:    Translation:Humans
    2. Cohen G, Rapoport B, Chan SW, Ruff P, Arance A, Mujika Eizmendi K, Houghton B, Brown MP, Zielinski RM, Mu?oz Couselo E, Lyle M, Anderson JR, Jain L, de Alwis D, Lala M, Akala O, Chartash E, Jacobs C. Pembrolizumab 400 mg every 6 weeks as first-line therapy for advanced melanoma (KEYNOTE-555): Results from cohort B of an open-label, phase 1 study. PLoS One. 2024; 19(11):e0309778. PMID: 39531423; PMCID: PMC11556718.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    3. Ubanako P, Mirza S, Ruff P, Penny C. Exosome-mediated delivery of siRNA molecules in cancer therapy: triumphs and challenges. Front Mol Biosci. 2024; 11:1447953. PMID: 39355533; PMCID: PMC11442288.
      Citations:    
    4. Ruff P. Editorial: Emerging mutations in colorectal cancer development and progression. Front Oncol. 2024; 14:1469129. PMID: 39263190; PMCID: PMC11387156.
      Citations: 1     
    5. O'Neil DS, Blanchard CL, Joffe M, Antoni M, Ream M, Mmoledi KC, Mkwanazi N, Shandukani V, Ruff P. Associations between HIV infection status, psychosocial factors, and adjuvant endocrine therapy adherence among South African women with early-stage breast cancer. Res Sq. 2024 Jun 27. PMID: 38978566; PMCID: PMC11230477.
      Citations:    
    6. Carbonell C, Adegbulugbe A, Cheung W, Ruff P. Barriers and Challenges to Implementing a Quality Improvement Program: Political and Administrative Challenges. JCO Glob Oncol. 2024 Jun; 10:e2300455. PMID: 38935883.
      Citations:    Fields:    Translation:Humans
    7. Joffe M, Ayeni OA, Mapanga W, Ruff P, Murugan N, Cubasch H, Norris SA. Perspectives on common chronic diseases in adult cancer patients in South Africa. Glob Health Action. 2023 12 31; 16(1):2228567. PMID: 37431748; PMCID: PMC10337486.
      Citations:    Fields:    Translation:Humans
    8. Mapanga W, Ayeni OA, Chen WC, Jacobson JS, Neugut AI, Ruff P, Cubasch H, O'Neil DS, Buccimazza I, Cacala S, Stopforth LW, Farrow HA, Nietz S, Phakathi B, Chirwa T, McCormack VA, Joffe M. The South African breast cancer and HIV outcomes study: Profiling the cancer centres and cohort characteristics, diagnostic pathways, and treatment approaches. PLOS Glob Public Health. 2023; 3(10):e0002432. PMID: 37874786; PMCID: PMC10597516.
      Citations: 1     
    9. Dix-Peek T, Dickens C, Augustine TN, Phakathi BP, Van Den Berg EJ, Joffe M, Ayeni OA, Cubasch H, Nietz S, Mathew CG, Hayat M, Neugut AI, Jacobson JS, Ruff P, Duarte RAB. FGFR2 genetic variants in women with breast cancer. Mol Med Rep. 2023 Dec; 28(6). PMID: 37830168; PMCID: PMC10619128.
      Citations:    Fields:    Translation:Humans
    10. O'Neil DS, Ayeni OA, Farrow HA, Chen WC, Demetriou G, Buccimazza I, Cacala S, Stopforth LW, Joffe M, Antoni MH, Lopes G, Pumpalova YS, Mapanga W, Jacobson JS, Crew KD, Neugut AI, Ruff P, Cubasch H. The Impact of HIV Infection on Neoadjuvant and Adjuvant Chemotherapy Relative Dose Intensity in South African Patients with Breast Cancer. Oncologist. 2023 10 03; 28(10):e921-e929. PMID: 36943395; PMCID: PMC10546819.
      Citations: 2     Fields:    Translation:Humans
    11. Tan SX, Pumpalova Y, Rogers AM, Bhatt K, Herbst CL, Ruff P, Neugut AI, Hur C. Cost-effectiveness of adjuvant chemotherapy for high-risk stage II and stage III colon cancer in South Africa. Cancer Med. 2023 07; 12(14):15515-15529. PMID: 37318753; PMCID: PMC10417185.
      Citations: 2     Fields:    Translation:Humans
    12. Phakathi B, Dix-Peek T, Van Den Berg E, Dickens C, Nietz S, Cubasch H, Joffe M, Neugut AI, Jacobson JS, Ruff P, Duarte R. PAM50 intrinsic subtypes, risk of recurrence score and breast cancer survival in HIV-positive and HIV-negative patients-a South African cohort study. Breast Cancer Res Treat. 2023 Aug; 200(3):337-346. PMID: 37266756; PMCID: PMC10300149.
      Citations: 2     Fields:    Translation:Humans
    13. Breiman RF, Demetriou G, Naidu G, Papathanasopoulos MA, Ruff P, Madhi SA. Shifting the center of gravity for addressing the rising cancer disease burden in Africa: A rationale for African-based integrative infectious diseases and oncology research. PLOS Glob Public Health. 2023; 3(5):e0001970. PMID: 37256858; PMCID: PMC10231805.
      Citations:    
    14. Chiwambutsa SM, Ayeni O, Kapungu N, Kanji C, Thelingwani R, Chen WC, Mokone DH, O'Neil DS, Neugut AI, Jacobson JS, Ruff P, Cubasch H, Joffe M, Masimirembwa C. Effects of Genetic Polymorphisms of Drug Metabolizing Enzymes and co-Medications on Tamoxifen Metabolism in Black South African Women with Breast Cancer. Clin Pharmacol Ther. 2023 07; 114(1):127-136. PMID: 37042388; PMCID: PMC11016593.
      Citations: 1     Fields:    Translation:Humans
    15. Dix-Peek T, Phakathi BP, van den Berg EJ, Dickens C, Augustine TN, Cubasch H, Neugut AI, Jacobson JS, Joffe M, Ruff P, Duarte RAB. Discordance between PAM50 intrinsic subtyping and immunohistochemistry in South African women with breast cancer. Breast Cancer Res Treat. 2023 May; 199(1):1-12. PMID: 36867282; PMCID: PMC10147771.
      Citations: 5     Fields:    Translation:Humans
    16. Mapanga W, Norris SA, Craig A, Ayeni OA, Chen WC, Jacobson JS, Neugut AI, Ruff P, Cubasch H, O'Neil DS, Buccimazza I, Cacala S, Stopforth LW, Farrow HA, Nietz S, Phakathi B, Chirwa T, McCormack VA, Joffe M. Drivers of disparities in stage at diagnosis among women with breast cancer: South African breast cancers and HIV outcomes cohort. PLoS One. 2023; 18(2):e0281916. PMID: 36795733; PMCID: PMC9934316.
      Citations: 4     Fields:    Translation:Humans
    17. Ayeni OA, Joffe M, Mapanga W, Chen WC, O'Neil DS, Phakathi B, Nietz S, Buccimazza I, Cacala S, Stopforth LW, Jacobson JS, Crew KD, Neugut AI, Ramiah D, Ruff P, Cubasch H, Chirwa T, McCormack V, Micklesfield LK, Norris SA. Multimorbidity and overall survival among women with breast cancer: results from the South African Breast Cancer and HIV Outcomes Study. Breast Cancer Res. 2023 01 23; 25(1):7. PMID: 36691057; PMCID: PMC9872426.
      Citations: 6     Fields:    Translation:HumansCells
    18. Mirza S, Bhadresha K, Mughal MJ, McCabe M, Shahbazi R, Ruff P, Penny C. Liquid biopsy approaches and immunotherapy in colorectal cancer for precision medicine: Are we there yet? Front Oncol. 2022; 12:1023565. PMID: 36686736; PMCID: PMC9853908.
      Citations: 6     
    19. Ayeni OA, Chiwambutsa S, Chen WC, Kapungu N, Kanji C, Thelingwani R, Murugan N, Mathiba R, Phakathi B, Nietz S, Ramiah D, O'Neil DS, Jacobson JS, Ruff P, Cubasch H, Chirwa T, Joffe M, Masimirembwa C, Neugut AI. The impact of HIV on non-adherence for tamoxifen among women with breast cancer in South Africa. Breast Cancer Res Treat. 2023 Feb; 197(3):647-659. PMID: 36538247; PMCID: PMC10149344.
      Citations: 7     Fields:    Translation:Humans
    20. Cicero KI, Joffe M, Patel M, Chiuzan C, Pentz A, Ruff P, Lentzsch S, Leng S, Jacobson JS, Rebbeck TR, Neugut AI. Prevalence of Monoclonal Gammopathy of Undetermined Significance in Black South African Men. Cancer Epidemiol Biomarkers Prev. 2022 12 05; 31(12):2192-2198. PMID: 36126958.
      Citations: 3     Fields:    Translation:Humans
    21. Bouter C, Puttergill B, Hyman GY, Maphosa S, Gaylard P, Etheredge H, Fabian J, Ruff P, Bebington B. Burn-injured patients - the preferably unheard. S Afr J Surg. 2022 Dec; 60(4):229-234. PMID: 36477050.
      Citations: 2     Fields:    Translation:Humans
    22. Wilkinson M, Gray AL, Wiseman R, Kredo T, Cohen K, Miot J, Blecher M, Ruff P, Johnson Y, Poluta M, McGee S, Leong TD, Brand M, Suleman F, Maramba E, Blockman M, Jugathpal J, Cleary S, Nematswerani N, Moodliar S, Parrish A, Jamaloodien KK, Stander T, MacQuilkan K, Crisp N, Wilkinson T. Health Technology Assessment in Support of National Health Insurance in South Africa. Int J Technol Assess Health Care. 2022 May 06; 38(1):e44. PMID: 35513309.
      Citations: 7     Fields:    
    23. Pumpalova YS, Ayeni OA, Chen WC, Buccimazza I, Cacala S, Stopforth LW, Farrow HA, Mapanga W, Nietz S, Phakathi B, Joffe M, McCormack V, Jacobson JS, Crew KD, Neugut AI, Ruff P, Cubasch H, O'Neil DS. The Impact of Breast Cancer Treatment Delays on Survival Among South African Women. Oncologist. 2022 03 11; 27(3):e233-e243. PMID: 35274708; PMCID: PMC8914482.
      Citations: 5     Fields:    Translation:Humans
    24. Ayeni OA, O'Neil DS, Pumpalova YS, Chen WC, Nietz S, Phakathi B, Buccimazza I, Cacala S, Stopforth LW, Farrow HA, Mapanga W, Joffe M, Chirwa T, McCormack V, Jacobson JS, Crew KD, Neugut AI, Ruff P, Cubasch H. Impact of HIV infection on survival among women with stage I-III breast cancer: Results from the South African breast cancer and HIV outcomes study. Int J Cancer. 2022 Jul 15; 151(2):209-221. PMID: 35218568.
      Citations: 10     Fields:    Translation:Humans
    25. Blanchard CL, Mmoledi K, Antoni MH, Demetriou G, Joffe M, Lopes G, Ruff P, O'Neil DS. Validating an Instrument for Direct Patient Reporting of Distress and Chemotherapy-Related Toxicity among South African Cancer Patients. Cancers (Basel). 2021 Dec 24; 14(1). PMID: 35008258; PMCID: PMC8750185.
      Citations:    
    26. Pumpalova Y, Rogers AM, Tan SX, Herbst CL, Ruff P, Neugut AI, Hur C. Modeling the Cost-Effectiveness of Adjuvant Chemotherapy for Stage III Colon Cancer in South African Public Hospitals. JCO Glob Oncol. 2021 12; 7:1730-1741. PMID: 34936375; PMCID: PMC8710350.
      Citations: 3     Fields:    Translation:Humans
    27. Neugut AI, El-Sadr WM, Ruff P. The Looming Threat: Cancer in Sub-Saharan Africa. Oncologist. 2021 12; 26(12):e2099-e2101. PMID: 34473874; PMCID: PMC8649061.
      Citations: 2     Fields:    Translation:Humans
    28. Blayney DW, Bariani G, Das D, Dawood S, Gnant M, De Guzman R, Martin SE, O'Mahony D, Roach A, Ruff P, Sampaio C, Sanchez JA, Vanderpuye V, Kamal A, Hendricks C. Spotlight on International Quality: COVID-19 and Its Impact on Quality Improvement in Cancer Care. JCO Glob Oncol. 2021 09; 7:1513-1521. PMID: 34714666; PMCID: PMC8563078.
      Citations: 2     Fields:    Translation:HumansCellsPHPublic Health
    29. Pumpalova YS, Ayeni OA, Chen WC, O'Neil DS, Nietz S, Phakathi B, Buccimazza I, Cacala S, Stopforth LW, Farrow HA, Joffe M, Mapanga W, Jacobson JS, Crew KD, Cubasch H, Ruff P, Neugut AI. Impact of HIV infection on overall survival among women with stage IV breast cancer in South Africa. Breast Cancer Res Treat. 2021 Aug; 189(1):285-296. PMID: 34125339; PMCID: PMC9034410.
      Citations: 3     Fields:    Translation:Humans
    30. Phakathi B, Nietz S, Cubasch H, Dickens C, Dix-Peek T, Joffe M, Neugut AI, Jacobson J, Duarte R, Ruff P. Survival of south african women with breast cancer receiving anti-retroviral therapy for HIV. Breast. 2021 Oct; 59:27-36. PMID: 34126376; PMCID: PMC8209274.
      Citations: 7     Fields:    Translation:Humans
    31. Grossheim L, Ruff P, Ngoma T, Vanderpuye V, Mwango G, Ochieng P, Palmer D, Kouya F, Lasebikan N, Ntekim A, Ngoma M, Bih N, Malloum A, Elzawawy A, Kerr D, Ngwa W. Cancer and COVID-19 Experiences at African Cancer Centers: The Silver Lining. JCO Glob Oncol. 2021 03; 7:410-415. PMID: 33760639; PMCID: PMC8081519.
      Citations: 9     Fields:    Translation:Humans
    32. Mapanga W, Norris SA, Chen WC, Blanchard C, Graham A, Baldwin-Ragaven L, Boyles T, Donde B, Greef L, Huddle K, Khumalo B, Leepile E, Lubuzo B, Makhutle R, Mayet Y, Tsitsi M, Mistri P, Mmoledi K, Ratshikana-Moloko M, Morer R, Pretorius L, Punwasi J, Richards GA, Ruff P, Shabalala D, Sibadela M, Soma N, Wong M, Joffe M. Consensus study on the health system and patient-related barriers for lung cancer management in South Africa. PLoS One. 2021; 16(2):e0246716. PMID: 33571312; PMCID: PMC7877667.
      Citations: 5     Fields:    Translation:Humans
    33. Toma A, O'Neil D, Joffe M, Ayeni O, Nel C, van den Berg E, Nayler S, Cubasch H, Phakathi B, Buccimazza I, Cacala S, Ruff P, Norris S, Nietz S. Quality of Histopathological Reporting in Breast Cancer: Results From Four South African Breast Units. JCO Glob Oncol. 2021 01; 7:72-80. PMID: 33434068; PMCID: PMC8081479.
      Citations: 7     Fields:    Translation:Humans
    34. Nietz S, Ruff P, Chen WC, O'Neil DS, Norris SA. Quality indicators for the diagnosis and surgical management of breast cancer in South Africa. Breast. 2020 Dec; 54:187-196. PMID: 33120084; PMCID: PMC7593621.
      Citations: 2     Fields:    Translation:Humans
    35. Price T, Ang A, Boedigheimer M, Kim TW, Li J, Cascinu S, Ruff P, Satya Suresh A, Thomas A, Tjulandin S, Peeters M. Frequency of S492R mutations in the epidermal growth factor receptor: analysis of plasma DNA from patients with metastatic colorectal cancer treated with panitumumab or cetuximab monotherapy. Cancer Biol Ther. 2020 10 02; 21(10):891-898. PMID: 33026965; PMCID: PMC7583702.
      Citations: 17     Fields:    Translation:Humans
    36. Nietz S, O'Neil DS, Ayeni O, Chen WC, Joffe M, Jacobson JS, Neugut AI, Ruff P, Mapanga W, Buccimazza I, Singh U, Cacala S, Stopforth L, Phakathi B, Chirwa T, Cubasch H. A comparison of complete pathologic response rates following neoadjuvant chemotherapy among South African breast cancer patients with and without concurrent HIV infection. Breast Cancer Res Treat. 2020 Dec; 184(3):861-872. PMID: 32875480; PMCID: PMC7658037.
      Citations: 8     Fields:    Translation:Humans
    37. Redondo A, Colombo N, McCormack M, Dreosti L, Nogueira-Rodrigues A, Scambia G, Lorusso D, Joly F, Schenker M, Ruff P, Estevez-Diz M, Irahara N, Donica M, Gonzalez-Martín A. Primary results from CECILIA, a global single-arm phase II study evaluating bevacizumab, carboplatin and paclitaxel for advanced cervical cancer. Gynecol Oncol. 2020 10; 159(1):142-149. PMID: 32763109.
      Citations: 15     Fields:    Translation:HumansCTClinical Trials
    38. Maponga TG, Glashoff RH, Vermeulen H, Robertson B, Burmeister S, Bernon M, Omoshoro-Jones J, Ruff P, Neugut AI, Jacobson JS, Preiser W, Andersson MI. Hepatitis B virus-associated hepatocellular carcinoma in South Africa in the era of HIV. BMC Gastroenterol. 2020 Jul 13; 20(1):226. PMID: 32660431; PMCID: PMC7359588.
      Citations: 10     Fields:    Translation:HumansCells
    39. Taniguchi H, Yamanaka T, Sakai D, Muro K, Yamazaki K, Nakata S, Kimura H, Ruff P, Kim TW, Peeters M, Price T. Efficacy of Panitumumab and Cetuximab in Patients with Colorectal Cancer Previously Treated with Bevacizumab; a Combined Analysis of Individual Patient Data from ASPECCT and WJOG6510G. Cancers (Basel). 2020 Jun 28; 12(7). PMID: 32605298; PMCID: PMC7407286.
      Citations: 6     
    40. Bouter C, Bebington B, Maphosa S, Maher H, Gaylard P, Etheredge HR, Fabian J, Prodehl L, Surridge D, Fourie RL, Harran N, Lutrin D, Bizos D, Ruff P. It's contrary - comorbidity does not affect survival of South Africans with colorectal cancer: An analysis from the Colorectal Cancer in South Africa cohort. S Afr Med J. 2020 Apr 29; 110(5):382-388. PMID: 32657722.
      Citations: 3     Fields:    Translation:Humans
    41. Herbst CL, Miot JK, Moch SL, Ruff P. Colorectal Cancer (CRC) treatment and associated costs in the public sector compared to the private sector in Johannesburg, South Africa. BMC Health Serv Res. 2020 Apr 07; 20(1):290. PMID: 32264964; PMCID: PMC7137465.
      Citations: 3     Fields:    Translation:Humans
    42. Ratshikana-Moloko M, Ayeni O, Tsitsi JM, Wong ML, Jacobson JS, Neugut AI, Sobekwa M, Joffe M, Mmoledi K, Blanchard CL, Mapanga W, Ruff P, Cubasch H, O'Neil DS, Balboni TA, Prigerson HG. Spiritual Care, Pain Reduction, and Preferred Place of Death Among Advanced Cancer Patients in Soweto, South Africa. J Pain Symptom Manage. 2020 07; 60(1):37-47. PMID: 32045675; PMCID: PMC7311268.
      Citations: 11     Fields:    Translation:Humans
    43. O'Neil DS, Chen WC, Ayeni O, Nietz S, Buccimazza I, Singh U, Cacala S, Stopforth L, Joffe M, Crew KD, Jacobson JS, Neugut AI, Ruff P, Cubasch H. Breast Cancer Care Quality in South Africa's Public Health System: An Evaluation Using American Society of Clinical Oncology/National Quality Forum Measures. J Glob Oncol. 2019 11; 5:1-16. PMID: 31770052; PMCID: PMC6882520.
      Citations: 15     Fields:    Translation:Humans
    44. Ayeni OA, Norris SA, Joffe M, Cubasch H, Nietz S, Buccimazza I, Singh U, Cacala S, Stopforth L, Chen WC, McCormack VA, O'Neil DS, Jacobson JS, Neugut AI, Ruff P, Micklesfield LK. The multimorbidity profile of South African women newly diagnosed with breast cancer. Int J Cancer. 2020 07 15; 147(2):361-374. PMID: 31600408; PMCID: PMC7649092.
      Citations: 11     Fields:    Translation:Humans
    45. Blanchard CL, Ayeni O, O'Neil DS, Prigerson HG, Jacobson JS, Neugut AI, Joffe M, Mmoledi K, Ratshikana-Moloko M, Sackstein PE, Ruff P. A Prospective Cohort Study of Factors Associated With Place of Death Among Patients With Late-Stage Cancer in Southern Africa. J Pain Symptom Manage. 2019 05; 57(5):923-932. PMID: 30708125; PMCID: PMC6531674.
      Citations: 13     Fields:    Translation:Humans
    46. Kandhavelu J, Subramanian K, Khan A, Omar A, Ruff P, Penny C. Computational Analysis of miRNA and their Gene Targets Significantly Involved in Colorectal Cancer Progression. Microrna. 2019; 8(1):68-75. PMID: 30073936.
      Citations: 11     Fields:    Translation:Humans
    47. Phakathi B, Cubasch H, Nietz S, Dickens C, Dix-Peek T, Joffe M, Neugut AI, Jacobson J, Duarte R, Ruff P. Clinico-pathological characteristics among South African women with breast cancer receiving anti-retroviral therapy for HIV. Breast. 2019 Feb; 43:123-129. PMID: 30550925; PMCID: PMC6369009.
      Citations: 11     Fields:    Translation:Humans
    48. O'Neil DS, Nietz S, Buccimazza I, Singh U, Cacala S, Stopforth LW, Joffe M, Jacobson JS, Neugut AI, Crew KD, Ruff P, Cubasch H. Neoadjuvant Chemotherapy Use for Nonmetastatic Breast Cancer at Five Public South African Hospitals and Impact on Time to Initial Cancer Therapy. Oncologist. 2019 07; 24(7):933-944. PMID: 30518615; PMCID: PMC6656461.
      Citations: 11     Fields:    Translation:Humans
    49. Peeters M, Price T, Boedigheimer M, Kim TW, Ruff P, Gibbs P, Thomas A, Demonty G, Hool K, Ang A. Evaluation of Emergent Mutations in Circulating Cell-Free DNA and Clinical Outcomes in Patients with Metastatic Colorectal Cancer Treated with Panitumumab in the ASPECCT Study. Clin Cancer Res. 2019 02 15; 25(4):1216-1225. PMID: 30487126.
      Citations: 22     Fields:    Translation:HumansCellsCTClinical Trials
    50. Shen MJ, Prigerson HG, Ratshikana-Moloko M, Mmoledi K, Ruff P, Jacobson JS, Neugut AI, Amanfu J, Cubasch H, Wong M, Joffe M, Blanchard C. Illness Understanding and End-of-Life Care Communication and Preferences for Patients With Advanced Cancer in South Africa. J Glob Oncol. 2018 09; 4:1-9. PMID: 30241251; PMCID: PMC6223439.
      Citations: 15     Fields:    Translation:Humans
    51. Raymond E, Kulke MH, Qin S, Yu X, Schenker M, Cubillo A, Lou W, Tomasek J, Thiis-Evensen E, Xu JM, Croitoru AE, Khasraw M, Sedlackova E, Borbath I, Ruff P, Oberstein PE, Ito T, Jia L, Hammel P, Shen L, Shrikhande SV, Shen Y, Sufliarsky J, Khan GN, Morizane C, Galdy S, Khosravan R, Fernandez KC, Rosbrook B, Fazio N. Efficacy and Safety of Sunitinib in Patients with Well-Differentiated Pancreatic Neuroendocrine Tumours. Neuroendocrinology. 2018; 107(3):237-245. PMID: 29991024.
      Citations: 20     Fields:    Translation:Humans
    52. Bebington B, Singh E, Fabian J, Jan Kruger C, Prodehl L, Surridge D, Penny C, McNamara L, Ruff P. Design and methodology of a study on colorectal cancer in Johannesburg, South Africa. JGH Open. 2018 Aug; 2(4):139-143. PMID: 30483579; PMCID: PMC6152464.
      Citations: 14     
    53. O'Neil DS, Prigerson HG, Mmoledi K, Sobekwa M, Ratshikana-Moloko M, Tsitsi JM, Cubasch H, Wong ML, Omoshoro-Jones JAO, Sackstein PE, Blinderman CD, Jacobson JS, Joffe M, Ruff P, Neugut AI, Blanchard CL. Informal Caregiver Challenges for Advanced Cancer Patients During End-of-Life Care in Johannesburg, South Africa and Distinctions Based on Place of Death. J Pain Symptom Manage. 2018 07; 56(1):98-106. PMID: 29604380; PMCID: PMC6082019.
      Citations: 8     Fields:    Translation:Humans
    54. Ruff P, Cubasch H, Joffe M, Rosenbaum E, Murugan N, Tsai MC, Ayeni O, Crew KD, Jacobson JS, Neugut AI. Neoadjuvant chemotherapy among patients treated for nonmetastatic breast cancer in a population with a high HIV prevalence in Johannesburg, South Africa. Cancer Manag Res. 2018; 10:279-286. PMID: 29467582; PMCID: PMC5811175.
      Citations: 5     
    55. Joffe M, Ayeni O, Norris SA, McCormack VA, Ruff P, Das I, Neugut AI, Jacobson JS, Cubasch H. Barriers to early presentation of breast cancer among women in Soweto, South Africa. PLoS One. 2018; 13(2):e0192071. PMID: 29394271; PMCID: PMC5796726.
      Citations: 35     Fields:    Translation:Humans
    56. Cubasch H, Dickens C, Joffe M, Duarte R, Murugan N, Tsai Chih M, Moodley K, Sharma V, Ayeni O, Jacobson JS, Neugut AI, McCormack V, Ruff P. Breast cancer survival in Soweto, Johannesburg, South Africa: A receptor-defined cohort of women diagnosed from 2009 to 11. Cancer Epidemiol. 2018 02; 52:120-127. PMID: 29306221; PMCID: PMC6127863.
      Citations: 23     Fields:    Translation:Humans
    57. Ruff P, Van Cutsem E, Lakomy R, Prausova J, van Hazel GA, Moiseyenko VM, Soussan-Lazard K, Dochy E, Magherini E, Macarulla T, Papamichael D. Observed benefit and safety of aflibercept in elderly patients with metastatic colorectal cancer: An age-based analysis from the randomized placebo-controlled phase III VELOUR trial. J Geriatr Oncol. 2018 01; 9(1):32-39. PMID: 28807738.
      Citations: 18     Fields:    Translation:HumansCTClinical Trials
    58. Cubasch H, Joffe M, Ruff P, Dietz D, Rosenbaum E, Murugan N, Chih MT, Ayeni O, Dickens C, Crew K, Jacobson JS, Neugut A. Breast conservation surgery versus total mastectomy among women with localized breast cancer in Soweto, South Africa. PLoS One. 2017; 12(8):e0182125. PMID: 28797046; PMCID: PMC5552305.
      Citations: 7     Fields:    Translation:Humans
    59. Cubasch H, Ruff P, Joffe M, Norris S, Chirwa T, Nietz S, Sharma V, Duarte R, Buccimazza I, Cacala S, Stopforth LW, Tsai WY, Stavsky E, Crew KD, Jacobson JS, Neugut AI. South African Breast Cancer and HIV Outcomes Study: Methods and Baseline Assessment. J Glob Oncol. 2017 Apr; 3(2):114-124. PMID: 28706996; PMCID: PMC5493271.
      Citations: 28     Fields:    
    60. Price T, Kim TW, Li J, Cascinu S, Ruff P, Suresh AS, Thomas A, Tjulandin S, Guan X, Peeters M. Final results and outcomes by prior bevacizumab exposure, skin toxicity, and hypomagnesaemia from ASPECCT: randomized phase 3 non-inferiority study of panitumumab versus cetuximab in chemorefractory wild-type KRAS exon 2 metastatic colorectal cancer. Eur J Cancer. 2016 11; 68:51-59. PMID: 27716478.
      Citations: 25     Fields:    Translation:HumansCTClinical Trials
    61. Van Cutsem E, Joulain F, Hoff PM, Mitchell E, Ruff P, Lakomý R, Prausová J, Moiseyenko VM, van Hazel G, Cunningham D, Arnold D, Schmoll HJ, Ten Tije AJ, McKendrick J, Kröning H, Humblet Y, Grávalos C, Le-Guennec S, Andria M, Dochy E, Vishwanath RL, Macarulla T, Tabernero J. Aflibercept Plus FOLFIRI vs. Placebo Plus FOLFIRI in Second-Line Metastatic Colorectal Cancer: a Post Hoc Analysis of Survival from the Phase III VELOUR Study Subsequent to Exclusion of Patients who had Recurrence During or Within 6 Months of Completing Adjuvant Oxaliplatin-Based Therapy. Target Oncol. 2016 06; 11(3):383-400. PMID: 26706237.
      Citations: 20     Fields:    Translation:HumansCTClinical Trials
    62. Moodley J, Stefan DC, Sewram V, Ruff P, Freeman M, Asante-Shongwe K. An overview of cancer research in South African academic and research institutions, 2013 - 2014. S Afr Med J. 2016 May 10; 106(6). PMID: 27245728.
      Citations: 2     Fields:    
    63. Siena S, Tabernero J, Bodoky G, Cunningham D, Rivera F, Ruff P, Canon JL, Koukakis R, Demonty G, Hechmati G, Douillard JY. Quality of life during first-line FOLFOX4±panitumumab in RAS wild-type metastatic colorectal carcinoma: results from a randomised controlled trial. ESMO Open. 2016; 1(2):e000041. PMID: 27843597; PMCID: PMC5070244.
      Citations: 7     
    64. Ruff P, Al-Sukhun S, Blanchard C, Shulman LN. Access to Cancer Therapeutics in Low- and Middle-Income Countries. Am Soc Clin Oncol Educ Book. 2016; 35:58-65. PMID: 27249686.
      Citations: 25     Fields:    Translation:Humans
    65. Singh E, Ruff P, Babb C, Sengayi M, Beery M, Khoali L, Kellett P, Underwood JM. Establishment of a cancer surveillance programme: the South African experience. Lancet Oncol. 2015 Aug; 16(8):e414-21. PMID: 26248849; PMCID: PMC4591917.
      Citations: 24     Fields:    Translation:HumansPHPublic Health
    66. Ruff P, Ferry DR, Lakom? R, Prausová J, Van Hazel GA, Hoff PM, Cunningham D, Arnold D, Schmoll HJ, Moiseyenko VM, McKendrick JJ, Ten Tije AJ, Vishwanath RL, Bhargava P, Chevalier S, Macarulla T, Van Cutsem E. Time course of safety and efficacy of aflibercept in combination with FOLFIRI in patients with metastatic colorectal cancer who progressed on previous oxaliplatin-based therapy. Eur J Cancer. 2015 Jan; 51(1):18-26. PMID: 25466509.
      Citations: 14     Fields:    Translation:Humans
    67. Singh E, Sengayi M, Urban M, Babb C, Kellett P, Ruff P. The South African National Cancer Registry: an update. Lancet Oncol. 2014 Aug; 15(9):e363. PMID: 25079099.
      Citations: 8     Fields:    Translation:Humans
    68. Price TJ, Peeters M, Ruff P, Murugappan S, Sidhu R. ASPECCT: panitumumab versus cetuximab for colorectal cancer--authors' reply. Lancet Oncol. 2014 Jul; 15(8):e303. PMID: 24988928.
      Citations: 1     Fields:    Translation:Humans
    69. Price TJ, Peeters M, Kim TW, Li J, Cascinu S, Ruff P, Suresh AS, Thomas A, Tjulandin S, Zhang K, Murugappan S, Sidhu R. Panitumumab versus cetuximab in patients with chemotherapy-refractory wild-type KRAS exon 2 metastatic colorectal cancer (ASPECCT): a randomised, multicentre, open-label, non-inferiority phase 3 study. Lancet Oncol. 2014 May; 15(6):569-79. PMID: 24739896.
      Citations: 173     Fields:    Translation:HumansCTClinical Trials
    70. Tabernero J, Van Cutsem E, Lakomý R, Prausová J, Ruff P, van Hazel GA, Moiseyenko VM, Ferry DR, McKendrick JJ, Soussan-Lazard K, Chevalier S, Allegra CJ. Aflibercept versus placebo in combination with fluorouracil, leucovorin and irinotecan in the treatment of previously treated metastatic colorectal cancer: prespecified subgroup analyses from the VELOUR trial. Eur J Cancer. 2014 Jan; 50(2):320-31. PMID: 24140268.
      Citations: 90     Fields:    Translation:HumansCTClinical Trials
    71. Douillard JY, Oliner KS, Siena S, Tabernero J, Burkes R, Barugel M, Humblet Y, Bodoky G, Cunningham D, Jassem J, Rivera F, Kocákova I, Ruff P, Blasinska-Morawiec M, Šmakal M, Canon JL, Rother M, Williams R, Rong A, Wiezorek J, Sidhu R, Patterson SD. Panitumumab-FOLFOX4 treatment and RAS mutations in colorectal cancer. N Engl J Med. 2013 Sep 12; 369(11):1023-34. PMID: 24024839.
      Citations: 1006     Fields:    Translation:Humans
    72. Van Cutsem E, Tabernero J, Lakomy R, Prenen H, Prausová J, Macarulla T, Ruff P, van Hazel GA, Moiseyenko V, Ferry D, McKendrick J, Polikoff J, Tellier A, Castan R, Allegra C. Addition of aflibercept to fluorouracil, leucovorin, and irinotecan improves survival in a phase III randomized trial in patients with metastatic colorectal cancer previously treated with an oxaliplatin-based regimen. J Clin Oncol. 2012 Oct 01; 30(28):3499-506. PMID: 22949147.
      Citations: 530     Fields:    Translation:HumansCTClinical Trials
    73. Abratt RP, Dreosti L, Ruff P. Cancer care in South Africa. Lancet Oncol. 2012 Aug; 13(8):e324. PMID: 22846830.
      Citations:    Fields:    Translation:Humans
    74. Douillard JY, Siena S, Cassidy J, Tabernero J, Burkes R, Barugel M, Humblet Y, Bodoky G, Cunningham D, Jassem J, Rivera F, Kocákova I, Ruff P, Blasinska-Morawiec M, Šmakal M, Canon JL, Rother M, Oliner KS, Wolf M, Gansert J. Randomized, phase III trial of panitumumab with infusional fluorouracil, leucovorin, and oxaliplatin (FOLFOX4) versus FOLFOX4 alone as first-line treatment in patients with previously untreated metastatic colorectal cancer: the PRIME study. J Clin Oncol. 2010 Nov 01; 28(31):4697-705. PMID: 20921465.
      Citations: 719     Fields:    Translation:HumansCTClinical Trials
    75. Gibbon VE, Penny CB, Strkalj G, Ruff P. Brief communication: Minimally invasive bone sampling method for DNA analysis. Am J Phys Anthropol. 2009 Aug; 139(4):596-9. PMID: 19350643.
      Citations:    Fields:    Translation:Humans
    76. Van Cutsem E, Köhne CH, Hitre E, Zaluski J, Chang Chien CR, Makhson A, D'Haens G, Pintér T, Lim R, Bodoky G, Roh JK, Folprecht G, Ruff P, Stroh C, Tejpar S, Schlichting M, Nippgen J, Rougier P. Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer. N Engl J Med. 2009 Apr 02; 360(14):1408-17. PMID: 19339720.
      Citations: 1540     Fields:    Translation:Humans
    77. Ruff P, Vorobiof DA, Jordaan JP, Demetriou GS, Moodley SD, Nosworthy AL, Werner ID, Raats J, Burgess LJ. A randomized, placebo-controlled, double-blind phase 2 study of docetaxel compared to docetaxel plus zosuquidar (LY335979) in women with metastatic or locally recurrent breast cancer who have received one prior chemotherapy regimen. Cancer Chemother Pharmacol. 2009 Sep; 64(4):763-8. PMID: 19241078.
      Citations: 26     Fields:    Translation:HumansCTClinical Trials
    78. Gibbon V, Paximadis M, Strkalj G, Ruff P, Penny C. Novel methods of molecular sex identification from skeletal tissue using the amelogenin gene. Forensic Sci Int Genet. 2009 Mar; 3(2):74-9. PMID: 19215875.
      Citations: 13     Fields:    Translation:HumansCells
    79. Ruff P, Schlaphoff T, du Toit E, Heyns A, Board of the South African Bone Marrow Registry. The South African Bone Marrow Registry (SABMR) and allogeneic bone marrow transplantation. S Afr Med J. 2008 Jul; 98(7):516, 518, 520. PMID: 18785385.
      Citations:    Fields:    Translation:Humans
    80. Stein L, Urban MI, O'Connell D, Yu XQ, Beral V, Newton R, Ruff P, Donde B, Hale M, Patel M, Sitas F. The spectrum of human immunodeficiency virus-associated cancers in a South African black population: results from a case-control study, 1995-2004. Int J Cancer. 2008 May 15; 122(10):2260-5. PMID: 18241034.
      Citations: 60     Fields:    Translation:HumansCells
    81. Gish RG, Porta C, Lazar L, Ruff P, Feld R, Croitoru A, Feun L, Jeziorski K, Leighton J, Gallo J, Kennealey GT. Phase III randomized controlled trial comparing the survival of patients with unresectable hepatocellular carcinoma treated with nolatrexed or doxorubicin. J Clin Oncol. 2007 Jul 20; 25(21):3069-75. PMID: 17634485.
      Citations: 82     Fields:    Translation:HumansCTClinical Trials
    82. Jacobs P, Ruff P, Wood L, Moodley D, Mansvelt E. Amyloidosis: a changing clinical perspective. Hematology. 2007 Apr; 12(2):163-7. PMID: 17454199.
      Citations:    Fields:    Translation:HumansCells
    83. Sitas F, Urban M, Stein L, Beral V, Ruff P, Hale M, Patel M, O'Connell D, Yu XQ, Verzijden A, Marais D, Williamson AL. The relationship between anti-HPV-16 IgG seropositivity and cancer of the cervix, anogenital organs, oral cavity and pharynx, oesophagus and prostate in a black South African population. Infect Agent Cancer. 2007 Mar 02; 2:6. PMID: 17331260; PMCID: PMC1821007.
      Citations: 20     
    84. Nyongesa C, Ruff P, Donde B, Kotzen J. A phase I study of concurrent cisplatin chemotherapy in patients with carcinoma of the cervix receiving pelvic radiotherapy. Int J Gynecol Cancer. 2006 Jul-Aug; 16(4):1614-9. PMID: 16884375.
      Citations: 11     Fields:    Translation:HumansCTClinical Trials
    85. Kuehr T, Ruff P, Rapoport BL, Falk S, Daniel F, Jacobs C, Davidson N, Thaler J, Boussard B, Carmichael J. Phase I/II study of first-line irinotecan combined with 5-fluorouracil and folinic acid Mayo Clinic schedule in patients with advanced colorectal cancer. BMC Cancer. 2004 Jul 16; 4:36. PMID: 15257756; PMCID: PMC493270.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    86. Wojcicki JM, Newton R, Urban MI, Stein L, Hale M, Patel M, Ruff P, Sur R, Bourboulia D, Sitas F. Risk factors for high anti-HHV-8 antibody titers (> or =1:51,200) in black, HIV-1 negative South African cancer patients: a case control study. BMC Infect Dis. 2003 Sep 12; 3:21. PMID: 12971827; PMCID: PMC222909.
      Citations: 3     Fields:    Translation:HumansCells
    87. Levine AM, Hancock BW, MacPhail P, Ruff P, Ashcroft RE. The treatment of AIDS-related cancers. Lancet Oncol. 2003 Sep; 4(9):576-81. PMID: 12965280.
      Citations:    Fields:    Translation:Humans
    88. Zampieri L, Bianchi P, Ruff P, Arbuthnot P. Differential modulation by estradiol of P-glycoprotein drug resistance protein expression in cultured MCF7 and T47D breast cancer cells. Anticancer Res. 2002 Jul-Aug; 22(4):2253-9. PMID: 12174911.
      Citations: 14     Fields:    Translation:HumansCells
    89. Sitas F, Pacella-Norman R, Carrara H, Patel M, Ruff P, Sur R, Jentsch U, Hale M, Rowji P, Saffer D, Connor M, Bull D, Newton R, Beral V. The spectrum of HIV-1 related cancers in South Africa. Int J Cancer. 2000 Nov 01; 88(3):489-92. PMID: 11054682.
      Citations: 49     Fields:    Translation:HumansCells
    90. Ruff P, Chishti AH, Grimm E, Bischoff D, Kim AC. Exon skipping truncates the PDZ domain of human erythroid p55 in a patient with chronic myeloid leukemia in acute megakaryoblastic blast crisis. Leuk Res. 1999 Mar; 23(3):247-50. PMID: 10071076.
      Citations: 2     Fields:    Translation:HumansCells
    91. Ruff P, Chasen MR, Long JE, van Rensburg CE. A phase II study of oral clofazimine in unresectable and metastatic hepatocellular carcinoma. Ann Oncol. 1998 Feb; 9(2):217-9. PMID: 9553669.
      Citations: 8     Fields:    Translation:HumansCTClinical Trials
    92. Ribeiro M, Ruff P, Falkson G. Low serum testosterone and a younger age predict for a poor outcome in metastatic prostate cancer. Am J Clin Oncol. 1997 Dec; 20(6):605-8. PMID: 9391550.
      Citations: 34     Fields:    Translation:Humans
    93. Sitas F, Bezwoda WR, Levin V, Ruff P, Kew MC, Hale MJ, Carrara H, Beral V, Fleming G, Odes R, Weaving A. Association between human immunodeficiency virus type 1 infection and cancer in the black population of Johannesburg and Soweto, South Africa. Br J Cancer. 1997; 75(11):1704-7. PMID: 9184191; PMCID: PMC2223539.
      Citations: 17     Fields:    Translation:HumansCells
    94. Panz VR, Ruff P, Joffe BI, Kedda MA, Seftel HC. SSCP analysis of the tyrosine kinase domain of the insulin receptor gene: polymorphisms detected in South African black and white subjects. Hum Genet. 1996 Apr; 97(4):438-40. PMID: 8834239.
      Citations: 2     Fields:    Translation:HumansCells
    95. Ruff P, Grimm E, Kim A. Molecular analysis of a silent polymorphism in the PDZ domain of p55, the major palmitoylated erythrocyte membrane protein. Hematopathol Mol Hematol. 1996; 10(4):187-91. PMID: 9042661.
      Citations:    Fields:    Translation:HumansCells
    96. Ruff P, Saragas E, Poulos M, Weaving A. Patterns of clonal evolution in transformed chronic myelogenous leukemia. Cancer Genet Cytogenet. 1995 Jun; 81(2):182-4. PMID: 7621419.
      Citations: 4     Fields:    Translation:HumansCells
    97. Stein ME, Spencer D, Ruff P. Lymphoproliferative malignancies in association with endemic African Kaposi's sarcoma. Cent Afr J Med. 1994 Jul; 40(7):176-8. PMID: 7812990.
      Citations:    Fields:    Translation:HumansPHPublic Health
    98. Stein M, Kantor A, Spencer D, Lakier R, Ruff P, Dale J. Radiation therapy in an elderly African population with Kaposi's sarcoma. Tumori. 1994 Apr 30; 80(2):139-40. PMID: 8016906.
      Citations:    Fields:    Translation:Humans
    99. Ruff P, Paska W, Goedhals L, Pouillart P, Rivière A, Vorobiof D, Bloch B, Jones A, Martin C, Brunet R, et al. Ondansetron compared with granisetron in the prophylaxis of cisplatin-induced acute emesis: a multicentre double-blind, randomised, parallel-group study. The Ondansetron and Granisetron Emesis Study Group. Oncology. 1994 Jan-Feb; 51(1):113-8. PMID: 8265095.
      Citations: 31     Fields:    Translation:HumansCTClinical Trials
    100. Stein ME, Lakier R, Kuten A, Spencer D, Ruff P, Bezwoda WR. Radiation therapy in endemic (African) Kaposi's sarcoma. Int J Radiat Oncol Biol Phys. 1993 Dec 01; 27(5):1181-4. PMID: 8262845.
      Citations:    Fields:    Translation:HumansCTClinical Trials
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