"Tretinoin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An important regulator of GENE EXPRESSION during growth and development, and in NEOPLASMS. Tretinoin, also known as retinoic acid and derived from maternal VITAMIN A, is essential for normal GROWTH; and EMBRYONIC DEVELOPMENT. An excess of tretinoin can be teratogenic. It is used in the treatment of PSORIASIS; ACNE VULGARIS; and several other SKIN DISEASES. It has also been approved for use in promyelocytic leukemia (LEUKEMIA, PROMYELOCYTIC, ACUTE).
| Descriptor ID |
D014212
|
| MeSH Number(s) |
D02.455.326.271.665.202.495.818.500 D02.455.426.392.368.367.379.249.700.860.500 D02.455.849.131.495.818.800 D23.767.261.700.780
|
| Concept/Terms |
Tretinoin- Tretinoin
- Retinoic Acid
- Acid, Retinoic
- Vitamin A Acid
- Acid, Vitamin A
- all-trans-Retinoic Acid
- Acid, all-trans-Retinoic
- all trans Retinoic Acid
- trans-Retinoic Acid
- Acid, trans-Retinoic
- trans Retinoic Acid
|
Below are MeSH descriptors whose meaning is more general than "Tretinoin".
Below are MeSH descriptors whose meaning is more specific than "Tretinoin".
This graph shows the total number of publications written about "Tretinoin" by people in this website by year, and whether "Tretinoin" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Tretinoin" by people in Profiles.
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The V2 loop of HIV gp120 delivers costimulatory signals to CD4+ T cells through Integrin a4ß7 and promotes cellular activation and infection. Proc Natl Acad Sci U S A. 2020 12 22; 117(51):32566-32573.
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The protective variant rs7173049 at LOXL1 locus impacts on retinoic acid signaling pathway in pseudoexfoliation syndrome. Hum Mol Genet. 2019 08 01; 28(15):2531-2548.
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Alitretinoin: A Review in Severe Chronic Hand Eczema. Drugs. 2016 Sep; 76(13):1271-1279.
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Retinoic acid increases the length and volume density of ducts in the rat embryonic pancreas. Dev Growth Differ. 2003 Apr; 45(2):199-207.
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Regulation of embryonic chick insulin cells: effect of retinoic acid and insulin-like growth factor 1. Cells Tissues Organs. 2001; 169(1):42-8.
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The effect of retinoic acid on the proportion of insulin cells in the developing chick pancreas. In Vitro Cell Dev Biol Anim. 2000 Jan; 36(1):14-8.