"Thrombin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme formed from PROTHROMBIN that converts FIBRINOGEN to FIBRIN.
| Descriptor ID |
D013917
|
| MeSH Number(s) |
D08.811.277.656.300.760.855 D08.811.277.656.959.350.855 D12.776.124.125.890 D23.119.960
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Thrombin".
Below are MeSH descriptors whose meaning is more specific than "Thrombin".
This graph shows the total number of publications written about "Thrombin" by people in this website by year, and whether "Thrombin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 2 | 2 |
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Below are the most recent publications written about "Thrombin" by people in Profiles.
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The thrombin generation capability of the Chacma baboon (Papio ursinus): implications for haemostatic disease models. Sci Rep. 2023 12 27; 13(1):22968.
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FRONTIER1: a partially randomized phase 2 study assessing the safety, pharmacokinetics, and pharmacodynamics of Mim8, a factor VIIIa mimetic. J Thromb Haemost. 2024 Apr; 22(4):990-1000.
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Dolutegravir potentiates platelet activation by a calcium-dependent, ionophore-like mechanism. J Immunotoxicol. 2022 12; 19(1):1-8.
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Submission for Special Issue: The Role of Platelet Activation in the Pathophysiology of HIV, Tuberculosis, and Pneumococcal Disease. Bedaquiline Suppresses ADP-Mediated Activation of Human Platelets In Vitro via Interference With Phosphatidylinositol 3-Kinase. Front Immunol. 2020; 11:621148.
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Reduction of prothrombin and Factor V levels following supplementation with omega-3 fatty acids is sex dependent: a randomised controlled study. J Nutr Biochem. 2014 Oct; 25(10):997-1002.
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Phase I, randomized, double-blind, placebo-controlled, single-dose escalation study of the recombinant factor VIIa variant BAY 86-6150 in hemophilia. J Thromb Haemost. 2012 May; 10(5):773-80.
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Endogenous thrombin potential for predicting risk of venous thromboembolism in carriers of factor V Leiden. Pathophysiol Haemost Thromb. 2006; 35(6):435-9.