"Necrosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The pathological process occurring in cells that are dying from irreparable injuries. It is caused by the progressive, uncontrolled action of degradative ENZYMES, leading to MITOCHONDRIAL SWELLING, nuclear flocculation, and cell lysis. It is distinct it from APOPTOSIS, which is a normal, regulated cellular process.
| Descriptor ID |
D009336
|
| MeSH Number(s) |
C23.550.717 G04.146.638
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Necrosis".
Below are MeSH descriptors whose meaning is more specific than "Necrosis".
This graph shows the total number of publications written about "Necrosis" by people in this website by year, and whether "Necrosis" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Necrosis" by people in Profiles.
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Inducing apoptosis using chemical treatment and acidic pH, and detecting it using the Annexin V flow cytometric assay. PLoS One. 2022; 17(6):e0270599.
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Folate-decorated, endostatin-loaded, nanoparticles for anti-proliferative chemotherapy in esophaegeal squamous cell carcinoma. Biomed Pharmacother. 2019 Nov; 119:109450.
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Dietary-induced obesity hastens the progression from concentric cardiac hypertrophy to pump dysfunction in spontaneously hypertensive rats. Hypertension. 2009 Dec; 54(6):1376-83.
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Susceptibility to systolic dysfunction in the myocardium from chronically infarcted spontaneously hypertensive rats. Am J Physiol Heart Circ Physiol. 2008 Jan; 294(1):H372-8.
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Chronic beta-adrenoreceptor activation increases cardiac cavity size through chamber remodeling and not via modifications in myocardial material properties. Am J Physiol Heart Circ Physiol. 2004 Dec; 287(6):H2762-7.
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The cytotoxic effects of a traditional Zulu remedy, impila (Callilepis laureola). Hum Exp Toxicol. 2002 Dec; 21(12):643-7.