N-Formylmethionine Leucyl-Phenylalanine
"N-Formylmethionine Leucyl-Phenylalanine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A formylated tripeptide originally isolated from bacterial filtrates that is positively chemotactic to polymorphonuclear leucocytes, and causes them to release lysosomal enzymes and become metabolically activated.
| Descriptor ID |
D009240
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| MeSH Number(s) |
D02.886.030.676.450.440 D12.125.072.050.685.445 D12.125.142.666.500 D12.125.166.676.450.440 D12.644.456.400 D23.125.685
|
| Concept/Terms |
N-Formylmethionine Leucyl-Phenylalanine- N-Formylmethionine Leucyl-Phenylalanine
- Leucyl-Phenylalanine, N-Formylmethionine
- N Formylmethionine Leucyl Phenylalanine
- Formylmethionyl-Leucyl-Phenylalanine
- Formylmethionyl Leucyl Phenylalanine
- N-Formyl-Methionyl-Leucyl-Phenylalanine
- N Formyl Methionyl Leucyl Phenylalanine
- Formylmet-Leu-Phe
- Formylmet Leu Phe
- Formylmethionylleucylphenylalanine
Formylmethionyl Peptide- Formylmethionyl Peptide
- Peptide, Formylmethionyl
- N-Formylated Peptide
- N Formylated Peptide
- Peptide, N-Formylated
|
Below are MeSH descriptors whose meaning is more general than "N-Formylmethionine Leucyl-Phenylalanine".
Below are MeSH descriptors whose meaning is more specific than "N-Formylmethionine Leucyl-Phenylalanine".
This graph shows the total number of publications written about "N-Formylmethionine Leucyl-Phenylalanine" by people in this website by year, and whether "N-Formylmethionine Leucyl-Phenylalanine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1998 | 1 | 0 | 1 |
| 1999 | 1 | 1 | 2 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 2 | 2 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
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Below are the most recent publications written about "N-Formylmethionine Leucyl-Phenylalanine" by people in Profiles.
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Calcium-dependent potentiation of the pro-inflammatory functions of human neutrophils by tigecycline in vitro. J Antimicrob Chemother. 2012 Jan; 67(1):130-7.
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Interactive inhibitory effects of formoterol and montelukast on activated human neutrophils. Eur Respir J. 2010 Dec; 36(6):1417-24.
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Pneumolysin induces release of matrix metalloproteinase-8 and -9 from human neutrophils. Eur Respir J. 2009 Nov; 34(5):1167-70.
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Leukotrienes C4 and D4 sensitize human neutrophils for hyperreactivity to chemoattractants. Inflamm Res. 2009 May; 58(5):263-8.
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Montelukast inhibits neutrophil pro-inflammatory activity by a cyclic AMP-dependent mechanism. Br J Pharmacol. 2009 Jan; 156(1):105-15.
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Pneumolysin potentiates oxidative inactivation of alpha-1-proteinase inhibitor by activated human neutrophils. Respir Med. 2004 Sep; 98(9):865-71.
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Pneumolysin activates the synthesis and release of interleukin-8 by human neutrophils in vitro. J Infect Dis. 2002 Aug 15; 186(4):562-5.
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Pneumolysin potentiates production of prostaglandin E(2) and leukotriene B(4) by human neutrophils. Infect Immun. 2001 May; 69(5):3494-6.
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Investigation of the anti-inflammatory and membrane-stabilizing potential of spiramycin in vitro. J Antimicrob Chemother. 2000 Aug; 46(2):269-71.
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Exposure of N-formyl-L-methionyl-L-leucyl-L-phenylalanine-activated human neutrophils to the Pseudomonas aeruginosa-derived pigment 1-hydroxyphenazine is associated with impaired calcium efflux and potentiation of primary granule enzyme release. Infect Immun. 1999 Oct; 67(10):5157-62.