"Immunosuppressive Agents" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-CELLS or by inhibiting the activation of HELPER CELLS. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of INTERLEUKINS and other CYTOKINES are emerging.
Descriptor ID |
D007166
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MeSH Number(s) |
D27.505.696.477.656
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Immunosuppressive Agents".
Below are MeSH descriptors whose meaning is more specific than "Immunosuppressive Agents".
This graph shows the total number of publications written about "Immunosuppressive Agents" by people in this website by year, and whether "Immunosuppressive Agents" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1996 | 0 | 1 | 1 |
2000 | 1 | 1 | 2 |
2002 | 1 | 0 | 1 |
2005 | 0 | 1 | 1 |
2008 | 0 | 1 | 1 |
2011 | 0 | 1 | 1 |
2016 | 1 | 0 | 1 |
2017 | 1 | 1 | 2 |
2018 | 0 | 1 | 1 |
2021 | 0 | 1 | 1 |
2024 | 2 | 0 | 2 |
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Below are the most recent publications written about "Immunosuppressive Agents" by people in Profiles.
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Impact of donor CYP3A5 genotype on pharmacokinetics of tacrolimus in South African paediatric liver transplant patients. S Afr Med J. 2024 Apr 24; 114(3b):e1367.
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Pregnancy after kidney and liver transplantation. S Afr Med J. 2024 Apr 24; 114(3b):e1240.
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Managing ANCA-associated vasculitis during the COVID-19 pandemic: results from an online survey. Rheumatol Int. 2021 Nov; 41(11):1941-1947.
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Thrombotic thrombocytopenic purpura: A 5-year tertiary care centre experience. J Clin Apher. 2019 Feb; 34(1):44-50.
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Interstitial lung disease in South Africans with systemic sclerosis. Rheumatol Int. 2018 Apr; 38(4):657-662.
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Treatment outcome in early diffuse cutaneous systemic sclerosis: the European Scleroderma Observational Study (ESOS). Ann Rheum Dis. 2017 Jul; 76(7):1207-1218.
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Biomarkers of Tolerance in Kidney Transplantation: Are We Predicting Tolerance or Response to Immunosuppressive Treatment? Am J Transplant. 2016 12; 16(12):3443-3457.
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Guidelines for the treatment of myelodysplastic syndromes (MDS) in South Africa. S Afr Med J. 2011 Nov 28; 101(12):900-6.
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The South African Bone Marrow Registry (SABMR) and allogeneic bone marrow transplantation. S Afr Med J. 2008 Jul; 98(7):516, 518, 520.
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The importance of clinical parameters when differentiating cholestatic hepatitis C virus from allograft rejection. Transplant Proc. 2005 Dec; 37(10):4397-402.