"Islets of Langerhans" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Irregular microscopic structures consisting of cords of endocrine cells that are scattered throughout the PANCREAS among the exocrine acini. Each islet is surrounded by connective tissue fibers and penetrated by a network of capillaries. There are four major cell types. The most abundant beta cells (50-80%) secrete INSULIN. Alpha cells (5-20%) secrete GLUCAGON. PP cells (10-35%) secrete PANCREATIC POLYPEPTIDE. Delta cells (~5%) secrete SOMATOSTATIN.
| Descriptor ID |
D007515
|
| MeSH Number(s) |
A03.734.414 A06.407.414
|
| Concept/Terms |
Islets of Langerhans- Islets of Langerhans
- Langerhans Islets
- Pancreatic Islets
- Islet, Pancreatic
- Islets, Pancreatic
- Pancreatic Islet
- Nesidioblasts
- Nesidioblast
- Pancreas, Endocrine
- Endocrine Pancreas
- Islands of Langerhans
- Langerhans Islands
- Islet Cells
- Cell, Islet
- Cells, Islet
- Islet Cell
|
Below are MeSH descriptors whose meaning is more general than "Islets of Langerhans".
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This graph shows the total number of publications written about "Islets of Langerhans" by people in this website by year, and whether "Islets of Langerhans" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 2000 | 2 | 0 | 2 |
| 2001 | 2 | 0 | 2 |
| 2002 | 2 | 0 | 2 |
| 2003 | 0 | 1 | 1 |
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Below are the most recent publications written about "Islets of Langerhans" by people in Profiles.
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Retinoic acid increases the length and volume density of ducts in the rat embryonic pancreas. Dev Growth Differ. 2003 Apr; 45(2):199-207.
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Absolute numbers versus proportions in the assessment of differentiation of beta-cells in the embryonic avian pancreas. Eur J Morphol. 2002 Jul; 40(3):153-9.
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Exogenous activin increases the proportion of insulin cells in the developing chick pancreas in culture. Cell Biol Int. 2002; 26(12):1057-64.
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The quest for factors regulating the development of chick embryonic insulin cells in vitro. Ital J Anat Embryol. 2001; 106(2 Suppl 1):451-8.
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Regulation of embryonic chick insulin cells: effect of retinoic acid and insulin-like growth factor 1. Cells Tissues Organs. 2001; 169(1):42-8.
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Relation between weight gain and beta-cell secretory activity and non-esterified fatty acid production in 7-year-old African children: results from the Birth to Ten study. Diabetologia. 2000 Aug; 43(8):978-85.
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The effect of retinoic acid on the proportion of insulin cells in the developing chick pancreas. In Vitro Cell Dev Biol Anim. 2000 Jan; 36(1):14-8.
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Fishing in the stream of diabetes: from measuring insulin to the control of fetal organogenesis. Biochem Soc Trans. 1996 May; 24(2):341-50.
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Immunological and insulin secretory studies on isolated porcine islets of Langerhans. J Endocrinol. 1990 Jul; 126(1):43-9.
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Porcine islet isolation, cellular composition and secretory response. Horm Metab Res. 1989 Nov; 21(11):590-5.