"Insulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).
| Descriptor ID |
D007328
|
| MeSH Number(s) |
D06.472.699.587.200.500.625 D12.644.548.586.200.500.625
|
| Concept/Terms |
Insulin- Insulin
- Insulin, Regular
- Regular Insulin
- Soluble Insulin
- Insulin, Soluble
|
Below are MeSH descriptors whose meaning is more general than "Insulin".
Below are MeSH descriptors whose meaning is more specific than "Insulin".
This graph shows the total number of publications written about "Insulin" by people in this website by year, and whether "Insulin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 1 | 1 | 2 |
| 2000 | 3 | 2 | 5 |
| 2001 | 0 | 2 | 2 |
| 2002 | 2 | 2 | 4 |
| 2003 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 2 | 2 |
| 2008 | 1 | 0 | 1 |
| 2009 | 0 | 3 | 3 |
| 2010 | 2 | 1 | 3 |
| 2012 | 0 | 3 | 3 |
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 3 | 3 |
| 2015 | 0 | 3 | 3 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 1 | 2 |
| 2019 | 1 | 2 | 3 |
| 2020 | 2 | 1 | 3 |
| 2022 | 0 | 1 | 1 |
| 2024 | 0 | 2 | 2 |
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Below are the most recent publications written about "Insulin" by people in Profiles.
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Implementation research: a protocol for two three-arm pragmatic randomised controlled trials on continuous glucose monitoring devices in people with type 1 diabetes in South Africa and Kenya. Trials. 2024 May 21; 25(1):331.
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An unmet need: Pancreatic beta cell replacement. S Afr Med J. 2024 Apr 24; 114(3b):e1249.
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Targeted proteomics identifies potential biomarkers of dysglycaemia, beta cell function and insulin sensitivity in Black African men and women. Diabetologia. 2023 01; 66(1):174-189.
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Endocrine profiling in patients with Fanconi anemia, homozygous for a FANCG founder mutation. Mol Genet Genomic Med. 2020 08; 8(8):e1351.
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Impact of metabolic and inflammatory changes on glomerular function beyond conventional risk factors in an urban South Africa community with prevalent obesity. Cardiovasc J Afr. 2020 Mar/Apr; 31(4):91-102.
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Maternal and neonatal outcomes following the introduction of oral hypoglycaemic agents for gestational diabetes mellitus were comparable to insulin monotherapy in two historical cohorts. S Afr Med J. 2020 Jan 29; 110(2):154-158.
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Adiposity Mediates the Association between the Dietary Inflammatory Index and Markers of Type 2 Diabetes Risk in Middle-Aged Black South African Women. Nutrients. 2019 May 31; 11(6).
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Audit of diabetic ketoacidosis management at a tertiary hospital in Johannesburg, South Africa. S Afr Med J. 2019 May 31; 109(6):407-411.
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Fat redistribution and accumulation of visceral adipose tissue predicts type 2 diabetes risk in middle-aged black South African women: a 13-year longitudinal study. Nutr Diabetes. 2019 03 27; 9(1):12.
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Review of a causal role of fructose-containing sugars in myocardial susceptibility to ischemia/reperfusion injury. Nutr Res. 2017 Jun; 42:11-19.