"Genes, Immunoglobulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Genes encoding the different subunits of the IMMUNOGLOBULINS, for example the IMMUNOGLOBULIN LIGHT CHAIN GENES and the IMMUNOGLOBULIN HEAVY CHAIN GENES. The heavy and light immunoglobulin genes are present as gene segments in the germline cells. The completed genes are created when the segments are shuffled and assembled (B-LYMPHOCYTE GENE REARRANGEMENT) during B-LYMPHOCYTE maturation. The gene segments of the human light and heavy chain germline genes are symbolized V (variable), J (joining) and C (constant). The heavy chain germline genes have an additional segment D (diversity).
Descriptor ID |
D005803
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MeSH Number(s) |
G05.360.340.024.340.335 G12.500.299
|
Concept/Terms |
Genes, Immunoglobulin- Genes, Immunoglobulin
- Immunoglobulin Genes
- Gene, Immunoglobulin
- Immunoglobulin Gene
- Genes, Ig
- Gene, Ig
- Ig Gene
- Ig Genes
|
Below are MeSH descriptors whose meaning is more general than "Genes, Immunoglobulin".
Below are MeSH descriptors whose meaning is more specific than "Genes, Immunoglobulin".
This graph shows the total number of publications written about "Genes, Immunoglobulin" by people in this website by year, and whether "Genes, Immunoglobulin" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2015 | 1 | 0 | 1 |
2016 | 0 | 1 | 1 |
2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Genes, Immunoglobulin" by people in Profiles.
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Inferred Allelic Variants of Immunoglobulin Receptor Genes: A System for Their Evaluation, Documentation, and Naming. Front Immunol. 2019; 10:435.
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Effects of Darwinian Selection and Mutability on Rate of Broadly Neutralizing Antibody Evolution during HIV-1 Infection. PLoS Comput Biol. 2016 05; 12(5):e1004940.
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Ability to develop broadly neutralizing HIV-1 antibodies is not restricted by the germline Ig gene repertoire. J Immunol. 2015 May 01; 194(9):4371-8.