"Cyclic AMP" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An adenine nucleotide containing one phosphate group which is esterified to both the 3'- and 5'-positions of the sugar moiety. It is a second messenger and a key intracellular regulator, functioning as a mediator of activity for a number of hormones, including epinephrine, glucagon, and ACTH.
| Descriptor ID |
D000242
|
| MeSH Number(s) |
D03.633.100.759.646.138.395 D13.695.462.200 D13.695.667.138.395 D13.695.827.068.395
|
| Concept/Terms |
Cyclic AMP- Cyclic AMP
- AMP, Cyclic
- Adenosine Cyclic-3',5'-Monophosphate
- Cyclic-3',5'-Monophosphate, Adenosine
- Adenosine Cyclic Monophosphate
- Cyclic Monophosphate, Adenosine
- Monophosphate, Adenosine Cyclic
- Adenosine Cyclic 3,5 Monophosphate
- Adenosine Cyclic 3',5'-Monophosphate
- 3',5'-Monophosphate, Adenosine Cyclic
- Adenosine Cyclic 3',5' Monophosphate
- Cyclic 3',5'-Monophosphate, Adenosine
|
Below are MeSH descriptors whose meaning is more general than "Cyclic AMP".
Below are MeSH descriptors whose meaning is more specific than "Cyclic AMP".
This graph shows the total number of publications written about "Cyclic AMP" by people in this website by year, and whether "Cyclic AMP" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 1999 | 0 | 1 | 1 |
| 2005 | 0 | 2 | 2 |
| 2008 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cyclic AMP" by people in Profiles.
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The beta-2-adrenoreceptor agonists, formoterol and indacaterol, but not salbutamol, effectively suppress the reactivity of human neutrophils in vitro. Mediators Inflamm. 2014; 2014:105420.
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Interactive inhibitory effects of formoterol and montelukast on activated human neutrophils. Eur Respir J. 2010 Dec; 36(6):1417-24.
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Montelukast inhibits neutrophil pro-inflammatory activity by a cyclic AMP-dependent mechanism. Br J Pharmacol. 2009 Jan; 156(1):105-15.
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Contractile responses to selective phosphodiesterase inhibitors following chronic beta-adrenoreceptor activation. Pflugers Arch. 2006 May; 452(2):155-63.
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Phosphodiesterase inhibition promotes the transition from compensated hypertrophy to cardiac dilatation in rats. Pflugers Arch. 2006 Jan; 451(4):526-33.
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Exposure of N-formyl-L-methionyl-L-leucyl-L-phenylalanine-activated human neutrophils to the Pseudomonas aeruginosa-derived pigment 1-hydroxyphenazine is associated with impaired calcium efflux and potentiation of primary granule enzyme release. Infect Immun. 1999 Oct; 67(10):5157-62.
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Anti-oxidative effects of theophylline on human neutrophils involve cyclic nucleotides and protein kinase A. Inflammation. 1998 Dec; 22(6):545-57.