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Connection

Patrick Arbuthnot to RNA Interference

This is a "connection" page, showing publications Patrick Arbuthnot has written about RNA Interference.
Connection Strength

6,766
  1. Progress and Prospects of Anti-HBV Gene Therapy Development. Int J Mol Sci. 2015 Jul 31; 16(8):17589-610.
    View in: PubMed
    Score: 0,487
  2. Inhibition of HBV replication in vivo using helper-dependent adenovirus vectors to deliver antiviral RNA interference expression cassettes. Antivir Ther. 2014; 19(4):363-73.
    View in: PubMed
    Score: 0,434
  3. Recent advances in developing nucleic acid-based HBV therapy. Future Microbiol. 2013 Nov; 8(11):1489-504.
    View in: PubMed
    Score: 0,432
  4. Efficient silencing of hepatitis B virus by helper-dependent adenovirus vector-mediated delivery of artificial antiviral primary micro RNAs. Microrna. 2012; 1(1):19-25.
    View in: PubMed
    Score: 0,380
  5. Therapeutic potential of adenoviral vectors for delivery of expressed RNAi activators. Expert Opin Drug Deliv. 2010 Dec; 7(12):1373-85.
    View in: PubMed
    Score: 0,352
  6. tRNA Lys3 promoter cassettes that efficiently express RNAi-activating antihepatitis B virus short hairpin RNAs. Biochem Biophys Res Commun. 2010 Aug 06; 398(4):640-6.
    View in: PubMed
    Score: 0,343
  7. Harnessing RNA interference for the treatment of viral infections. Drug News Perspect. 2010 Jul-Aug; 23(6):341-50.
    View in: PubMed
    Score: 0,343
  8. Inhibition of hepatitis B virus replication with linear DNA sequences expressing antiviral micro-RNA shuttles. Biochem Biophys Res Commun. 2009 Nov 20; 389(3):484-9.
    View in: PubMed
    Score: 0,324
  9. Efficient silencing of gene expression with modular trimeric Pol II expression cassettes comprising microRNA shuttles. Nucleic Acids Res. 2009 Jul; 37(13):e91.
    View in: PubMed
    Score: 0,318
  10. Hepatic delivery of RNA interference activators for therapeutic application. Curr Gene Ther. 2009 Apr; 9(2):91-103.
    View in: PubMed
    Score: 0,314
  11. Harnessing the RNA interference pathway to advance treatment and prevention of hepatocellular carcinoma. World J Gastroenterol. 2008 Mar 21; 14(11):1670-81.
    View in: PubMed
    Score: 0,293
  12. Opportunities for treating chronic hepatitis B and C virus infection using RNA interference. J Viral Hepat. 2007 Jul; 14(7):447-59.
    View in: PubMed
    Score: 0,278
  13. Effective anti-hepatitis B virus hammerhead ribozymes derived from multimeric precursors. Oligonucleotides. 2007; 17(1):104-12.
    View in: PubMed
    Score: 0,269
  14. Effective inhibition of HBV replication in vivo by anti-HBx short hairpin RNAs. Mol Ther. 2006 Feb; 13(2):411-21.
    View in: PubMed
    Score: 0,250
  15. Exploiting the RNA interference pathway to counter hepatitis B virus replication. Liver Int. 2005 Feb; 25(1):9-15.
    View in: PubMed
    Score: 0,236
  16. How successful has targeted RNA interference for hepatic fibrosis been? Expert Opin Biol Ther. 2018 04; 18(4):381-388.
    View in: PubMed
    Score: 0,144
  17. Hepatic Delivery of Artificial Micro RNAs Using Helper-Dependent Adenoviral Vectors. Methods Mol Biol. 2016; 1364:249-60.
    View in: PubMed
    Score: 0,125
  18. Differing prospects for the future of using gene therapy to treat infections with hepatitis B virus and hepatitis C virus. Discov Med. 2015 Sep; 20(109):137-43.
    View in: PubMed
    Score: 0,123
  19. Recent advances in use of gene therapy to treat hepatitis B virus infection. Adv Exp Med Biol. 2015; 848:31-49.
    View in: PubMed
    Score: 0,117
  20. Sustained inhibition of hepatitis B virus replication in vivo using RNAi-activating lentiviruses. Gene Ther. 2015 Feb; 22(2):163-71.
    View in: PubMed
    Score: 0,116
  21. Inhibition of hepatitis B virus replication in cultured cells and in vivo using 2'-O-guanidinopropyl modified siRNAs. Bioorg Med Chem. 2013 Oct 15; 21(20):6145-55.
    View in: PubMed
    Score: 0,104
  22. Impact of sustained RNAi-mediated suppression of cellular cofactor Tat-SF1 on HIV-1 replication in CD4+ T cells. Virol J. 2012 Nov 15; 9:272.
    View in: PubMed
    Score: 0,101
  23. MicroRNA-like antivirals. Biochim Biophys Acta. 2011 Nov-Dec; 1809(11-12):746-55.
    View in: PubMed
    Score: 0,091
  24. Deriving four functional anti-HIV siRNAs from a single Pol III-generated transcript comprising two adjacent long hairpin RNA precursors. Nucleic Acids Res. 2010 Oct; 38(19):6652-63.
    View in: PubMed
    Score: 0,085
  25. Design of RNAi hairpins for mutation-specific silencing of ataxin-7 and correction of a SCA7 phenotype. PLoS One. 2009 Sep 30; 4(9):e7232.
    View in: PubMed
    Score: 0,081
  26. RNA interference-based gene expression strategies aimed at sustained therapeutic inhibition of HIV. Curr Top Med Chem. 2009; 9(12):1065-78.
    View in: PubMed
    Score: 0,077
  27. Efficient inhibition of hepatitis B virus replication in vivo, using polyethylene glycol-modified adenovirus vectors. Hum Gene Ther. 2008 Nov; 19(11):1325-31.
    View in: PubMed
    Score: 0,076
  28. The efficacy of generating three independent anti-HIV-1 siRNAs from a single U6 RNA Pol III-expressed long hairpin RNA. PLoS One. 2008 Jul 02; 3(7):e2602.
    View in: PubMed
    Score: 0,075
  29. Expressed anti-HBV primary microRNA shuttles inhibit viral replication efficiently in vitro and in vivo. Mol Ther. 2008 Jun; 16(6):1105-12.
    View in: PubMed
    Score: 0,074
  30. Specific inhibition of HBV replication in vitro and in vivo with expressed long hairpin RNA. Mol Ther. 2007 Mar; 15(3):534-41.
    View in: PubMed
    Score: 0,067
  31. The inhibitory efficacy of RNA POL III-expressed long hairpin RNAs targeted to untranslated regions of the HIV-1 5' long terminal repeat. Oligonucleotides. 2007; 17(4):419-31.
    View in: PubMed
    Score: 0,067
  32. Silencing of HIV-1 subtype C primary isolates by expressed small hairpin RNAs targeted to gag. AIDS Res Hum Retroviruses. 2006 May; 22(5):401-10.
    View in: PubMed
    Score: 0,064
  33. In Vivo Delivery of Cassettes Encoding Anti-HBV Primary MicroRNAs Using an Ancestral Adeno-Associated Viral Vector. Methods Mol Biol. 2020; 2115:171-183.
    View in: PubMed
    Score: 0,041
  34. Successful disabling of the 5' UTR of HCV using adeno-associated viral vectors to deliver modular multimeric primary microRNA mimics. J Virol Methods. 2016 09; 235:26-33.
    View in: PubMed
    Score: 0,032
  35. Construction of mismatched inverted repeat (IR) silencing vectors for maximizing IR stability and effective gene silencing in plants. Methods Mol Biol. 2015; 1287:295-304.
    View in: PubMed
    Score: 0,029
  36. Pathogenic effects of Rift Valley fever virus NSs gene are alleviated in cultured cells by expressed antiviral short hairpin RNAs. Antivir Ther. 2012; 17(4):643-56.
    View in: PubMed
    Score: 0,024
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.