"Exfoliation Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The deposition of flaky, translucent fibrillar material most conspicuous on the anterior lens capsule and pupillary margin but also in both surfaces of the iris, the zonules, trabecular meshwork, ciliary body, corneal endothelium, and orbital blood vessels. It sometimes forms a membrane on the anterior iris surface. Exfoliation refers to the shedding of pigment by the iris. (Newell, Ophthalmology, 7th ed, p380)
Descriptor ID |
D017889
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MeSH Number(s) |
C11.941.375.285
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Concept/Terms |
Exfoliation Syndrome- Exfoliation Syndrome
- Exfoliation Syndromes
- Syndrome, Exfoliation
- Syndromes, Exfoliation
- Pseudoexfoliation Syndrome
- Pseudoexfoliation Syndromes
- Syndrome, Pseudoexfoliation
- Syndromes, Pseudoexfoliation
- Exfoliation Glaucoma
- Exfoliative Syndrome
- Exfoliative Syndromes
- Syndrome, Exfoliative
- Syndromes, Exfoliative
- Pseudoexfoliation Of The Lens
- Glaucoma Capsulare
- Pseudo-Exfoliation Syndrome
- Pseudo Exfoliation Syndrome
- Pseudo-Exfoliation Syndromes
- Syndrome, Pseudo-Exfoliation
- Syndromes, Pseudo-Exfoliation
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Below are MeSH descriptors whose meaning is more general than "Exfoliation Syndrome".
Below are MeSH descriptors whose meaning is more specific than "Exfoliation Syndrome".
This graph shows the total number of publications written about "Exfoliation Syndrome" by people in this website by year, and whether "Exfoliation Syndrome" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2010 | 1 | 0 | 1 |
2012 | 1 | 0 | 1 |
2015 | 2 | 0 | 2 |
2017 | 1 | 0 | 1 |
2019 | 1 | 0 | 1 |
2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Exfoliation Syndrome" by people in Profiles.
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Association of Rare CYP39A1 Variants With Exfoliation Syndrome Involving the Anterior Chamber of the Eye. JAMA. 2021 02 23; 325(8):753-764.
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The protective variant rs7173049 at LOXL1 locus impacts on retinoic acid signaling pathway in pseudoexfoliation syndrome. Hum Mol Genet. 2019 08 01; 28(15):2531-2548.
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Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci. Nat Genet. 2017 07; 49(7):993-1004.
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Genetic variants and cellular stressors associated with exfoliation syndrome modulate promoter activity of a lncRNA within the LOXL1 locus. Hum Mol Genet. 2015 Nov 15; 24(22):6552-63.
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A common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome. Nat Genet. 2015 Apr; 47(4):387-92.
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The role of lysyl oxidase-like 1 DNA copy number variants in exfoliation glaucoma. Mol Vis. 2012; 18:2976-81.
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Major LOXL1 risk allele is reversed in exfoliation glaucoma in a black South African population. Mol Vis. 2010 Apr 21; 16:705-12.