"Leukotriene Antagonists" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of drugs designed to prevent leukotriene synthesis or activity by blocking binding at the receptor level.
| Descriptor ID |
D020024
|
| MeSH Number(s) |
D06.347.565 D27.505.696.399.450.565
|
| Concept/Terms |
Leukotriene Antagonists- Leukotriene Antagonists
- Receptor Antagonists, Leukotriene
- Antagonists, Leukotriene Receptor
- Leukotriene Receptor Antagonists
- Antagonists, Leukotriene
|
Below are MeSH descriptors whose meaning is more general than "Leukotriene Antagonists".
Below are MeSH descriptors whose meaning is more specific than "Leukotriene Antagonists".
This graph shows the total number of publications written about "Leukotriene Antagonists" by people in this website by year, and whether "Leukotriene Antagonists" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 1 | 2 |
| 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Leukotriene Antagonists" by people in Profiles.
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Cysteinyl leukotriene receptor-1 antagonists as modulators of innate immune cell function. J Immunol Res. 2014; 2014:608930.
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Montelukast: more than a cysteinyl leukotriene receptor antagonist? ScientificWorldJournal. 2010 Dec 14; 10:2403-13.
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Interactive inhibitory effects of formoterol and montelukast on activated human neutrophils. Eur Respir J. 2010 Dec; 36(6):1417-24.
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Leukotrienes C4 and D4 sensitize human neutrophils for hyperreactivity to chemoattractants. Inflamm Res. 2009 May; 58(5):263-8.
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Montelukast inhibits neutrophil pro-inflammatory activity by a cyclic AMP-dependent mechanism. Br J Pharmacol. 2009 Jan; 156(1):105-15.
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Guideline for the management of chronic asthma in adults--2000 update. South African Pulmonology Society Adult Asthma Working Group. S Afr Med J. 2000 May; 90(5 Pt 2):540-1, 544-52.