"beta Catenin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multi-functional catenin that participates in CELL ADHESION and nuclear signaling. Beta catenin binds CADHERINS and helps link their cytoplasmic tails to the ACTIN in the CYTOSKELETON via ALPHA CATENIN. It also serves as a transcriptional co-activator and downstream component of WNT PROTEIN-mediated SIGNAL TRANSDUCTION PATHWAYS.
| Descriptor ID |
D051176
|
| MeSH Number(s) |
D12.776.091.249 D12.776.220.145.500 D12.776.930.130
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "beta Catenin".
Below are MeSH descriptors whose meaning is more specific than "beta Catenin".
This graph shows the total number of publications written about "beta Catenin" by people in this website by year, and whether "beta Catenin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 1 | 2 |
| 2009 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "beta Catenin" by people in Profiles.
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Synthesis and Cytotoxic Activity of 1,2,4-Triazolo-Linked Bis-Indolyl Conjugates as Dual Inhibitors of Tankyrase and PI3K. Molecules. 2022 Nov 07; 27(21).
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Increased expression of ErbB-2 in liver is associated with hepatitis B x antigen and shorter survival in patients with liver cancer. Int J Cancer. 2009 Oct 15; 125(8):1894-901.
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Enhanced cell survival of Hep3B cells by the hepatitis B x antigen effector, URG11, is associated with upregulation of beta-catenin. Hepatology. 2006 Mar; 43(3):415-24.
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Downregulation of E-cadherin by hepatitis B virus X antigen in hepatocellullar carcinoma. Oncogene. 2006 Feb 16; 25(7):1008-17.