Polymorphism, Single-Stranded Conformational
"Polymorphism, Single-Stranded Conformational" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Variation in a population's DNA sequence that is detected by determining alterations in the conformation of denatured DNA fragments. Denatured DNA fragments are allowed to renature under conditions that prevent the formation of double-stranded DNA and allow secondary structure to form in single stranded fragments. These fragments are then run through polyacrylamide gels to detect variations in the secondary structure that is manifested as an alteration in migration through the gels.
| Descriptor ID |
D018807
|
| MeSH Number(s) |
G05.365.795.600
|
| Concept/Terms |
Polymorphism, Single-Stranded Conformational- Polymorphism, Single-Stranded Conformational
- Polymorphism, Single Stranded Conformational
- SSCP
- Single-Stranded Conformational Polymorphism
- Conformational Polymorphism, Single-Stranded
- Conformational Polymorphisms, Single-Stranded
- Polymorphisms, Single-Stranded Conformational
- Single Stranded Conformational Polymorphism
- Single-Stranded Conformational Polymorphisms
|
Below are MeSH descriptors whose meaning is more general than "Polymorphism, Single-Stranded Conformational".
Below are MeSH descriptors whose meaning is more specific than "Polymorphism, Single-Stranded Conformational".
This graph shows the total number of publications written about "Polymorphism, Single-Stranded Conformational" by people in this website by year, and whether "Polymorphism, Single-Stranded Conformational" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 2 | 2 |
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 2 | 2 |
| 1999 | 1 | 0 | 1 |
| 2000 | 0 | 3 | 3 |
| 2001 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
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Below are the most recent publications written about "Polymorphism, Single-Stranded Conformational" by people in Profiles.
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Evaluation of a species-specific PCR assay for the Anopheles funestus group from eleven African countries and Madagascar. Trans R Soc Trop Med Hyg. 2004 Mar; 98(3):142-7.
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False detection of Plasmodium falciparum sporozoites in Anopheles marshallii group mosquitoes. J Am Mosq Control Assoc. 2001 Sep; 17(3):160-5.
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Phylogenetic analysis of human herpesvirus-8 in South Africa and identification of a novel subgroup. J Gen Virol. 2000 Aug; 81(Pt 8):2029-2038.
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Inhibition of cholesterol synthesis by atorvastatin in homozygous familial hypercholesterolaemia. Atherosclerosis. 2000 Jun; 150(2):421-8.
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Identification of P gene mutations in individuals with oculocutaneous albinism in sub-Saharan Africa. Hum Mutat. 2000; 15(2):166-72.
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Single-strand conformation polymorphism analysis for identification of four members of the Anopheles funestus (Diptera: Culicidae) group. J Med Entomol. 1999 Mar; 36(2):125-30.
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Mutation analysis in familial hypercholesterolemia patients of different ancestries: identification of three novel LDLR gene mutations. Mol Cell Probes. 1998 Jun; 12(3):149-52.
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Two novel and two known low-density lipoprotein receptor gene mutations in German patients with familial hypercholesterolemia. Hum Mutat. 1998; Suppl 1:S232-3.
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CpG hotspot mutations at the LDL receptor locus are a frequent cause of familial hypercholesterolaemia among South African Indians. Clin Genet. 1997 Jun; 51(6):394-8.
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SSCP analysis of the tyrosine kinase domain of the insulin receptor gene: polymorphisms detected in South African black and white subjects. Hum Genet. 1996 Apr; 97(4):438-40.