"Neutrophil Activation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process in which the neutrophil is stimulated by diverse substances, resulting in degranulation and/or generation of reactive oxygen products, and culminating in the destruction of invading pathogens. The stimulatory substances, including opsonized particles, immune complexes, and chemotactic factors, bind to specific cell-surface receptors on the neutrophil.
| Descriptor ID |
D018375
|
| MeSH Number(s) |
G12.604
|
| Concept/Terms |
Neutrophil Activation- Neutrophil Activation
- Activation, Neutrophil
- Activations, Neutrophil
- Neutrophil Activations
|
Below are MeSH descriptors whose meaning is more general than "Neutrophil Activation".
Below are MeSH descriptors whose meaning is more specific than "Neutrophil Activation".
This graph shows the total number of publications written about "Neutrophil Activation" by people in this website by year, and whether "Neutrophil Activation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 2 | 2 |
| 1999 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Neutrophil Activation" by people in Profiles.
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Pro-inflammatory interactions of streptolysin O toxin with human neutrophils in vitro. J Immunotoxicol. 2024 Dec; 21(1):2345152.
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Pneumolysin mediates heterotypic aggregation of neutrophils and platelets in vitro. J Infect. 2017 06; 74(6):599-608.
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Pharmacological approaches to regulate neutrophil activity. Semin Immunopathol. 2013 Jul; 35(4):395-409.
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Characterization of the interactions of the pneumolysoid, ?6 PLY, with human neutrophils in vitro. Vaccine. 2011 Nov 08; 29(48):8780-2.
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Interactive inhibitory effects of formoterol and montelukast on activated human neutrophils. Eur Respir J. 2010 Dec; 36(6):1417-24.
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Montelukast inhibits neutrophil pro-inflammatory activity by a cyclic AMP-dependent mechanism. Br J Pharmacol. 2009 Jan; 156(1):105-15.
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Pneumolysin-mediated activation of NFkappaB in human neutrophils is antagonized by docosahexaenoic acid. Clin Exp Immunol. 2005 May; 140(2):274-81.
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Pneumolysin potentiates oxidative inactivation of alpha-1-proteinase inhibitor by activated human neutrophils. Respir Med. 2004 Sep; 98(9):865-71.
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Pneumolysin activates the synthesis and release of interleukin-8 by human neutrophils in vitro. J Infect Dis. 2002 Aug 15; 186(4):562-5.
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Exposure of N-formyl-L-methionyl-L-leucyl-L-phenylalanine-activated human neutrophils to the Pseudomonas aeruginosa-derived pigment 1-hydroxyphenazine is associated with impaired calcium efflux and potentiation of primary granule enzyme release. Infect Immun. 1999 Oct; 67(10):5157-62.