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Shabir Madhi to Streptococcus pneumoniae

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This is a "connection" page, showing publications Shabir Madhi has written about Streptococcus pneumoniae.
Shabir Madhi
Connection Strength
15,934
Streptococcus pneumoniae
  1. Serotype-specific serum immunoglobulin G at 18 months of age following one or two doses of a primary series of 10-valent or 13-valent pneumococcal conjugate vaccine and a booster dose at nine months of age: a randomized controlled study. Expert Rev Vaccines. 2025 Dec; 24(1):121-127.
    View in: PubMed
    Score: 0,786
  2. Single priming and a booster dose of 10-valent and 13-valent pneumococcal conjugate vaccine (PCV) maintains suppression of vaccine serotype colonization in South African children at 3, 4, and 5 years of age: a single-centre, open-labelled, randomized trial. Expert Rev Vaccines. 2024 Jan-Dec; 23(1):1011-1019.
    View in: PubMed
    Score: 0,772
  3. Streptococcus pneumoniae and other bacterial nasopharyngeal colonization seven years post-introduction of 13-valent pneumococcal conjugate vaccine in South African children. Int J Infect Dis. 2023 Sep; 134:45-52.
    View in: PubMed
    Score: 0,699
  4. Single priming and booster dose of ten-valent and 13-valent pneumococcal conjugate vaccines and Streptococcus pneumoniae colonisation in children in South Africa: a single-centre, open-label, randomised trial. Lancet Child Adolesc Health. 2023 05; 7(5):326-335.
    View in: PubMed
    Score: 0,691
  5. Pneumococcal Conjugate Vaccine Protection against Coronavirus-Associated Pneumonia Hospitalization in Children Living with and without HIV. mBio. 2021 01 08; 12(1).
    View in: PubMed
    Score: 0,594
  6. Residual colonization by vaccine serotypes in rural South Africa four years following initiation of pneumococcal conjugate vaccine immunization. Expert Rev Vaccines. 2020 04; 19(4):383-393.
    View in: PubMed
    Score: 0,564
  7. Effect of HIV-exposure and timing of antiretroviral treatment initiation in children living with HIV on antibody persistence and memory responses to Haemophilus influenzae type b and pneumococcal polysaccharide-protein conjugate vaccines. Vaccine. 2020 03 10; 38(12):2651-2659.
    View in: PubMed
    Score: 0,558
  8. Performance of the Biomark HD real-time qPCR System (Fluidigm) for the detection of nasopharyngeal bacterial pathogens and Streptococcus pneumoniae typing. Sci Rep. 2019 04 24; 9(1):6494.
    View in: PubMed
    Score: 0,527
  9. Comparison of traditional culture and molecular qPCR for detection of simultaneous carriage of multiple pneumococcal serotypes in African children. Sci Rep. 2017 07 05; 7(1):4628.
    View in: PubMed
    Score: 0,465
  10. Temporal Changes in Pneumococcal Colonization in HIV-infected and HIV-uninfected Mother-Child Pairs Following Transitioning From 7-valent to 13-valent Pneumococcal Conjugate Vaccine, Soweto, South Africa. J Infect Dis. 2015 Oct 01; 212(7):1082-92.
    View in: PubMed
    Score: 0,397
  11. Acquisition of Streptococcus pneumoniae in South African children vaccinated with 7-valent pneumococcal conjugate vaccine at 6, 14 and 40 weeks of age. Vaccine. 2015 Jan 29; 33(5):628-34.
    View in: PubMed
    Score: 0,390
  12. Temporal association of infant immunisation with pneumococcal conjugate vaccine on the ecology of Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus nasopharyngeal colonisation in a rural South African community. Vaccine. 2014 Sep 22; 32(42):5520-30.
    View in: PubMed
    Score: 0,380
  13. Interrelationship of Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus colonization within and between pneumococcal-vaccine naïve mother-child dyads. BMC Infect Dis. 2013 Oct 17; 13:483.
    View in: PubMed
    Score: 0,360
  14. Association of Streptococcus pneumoniae common protein antigen (CPA) antibodies and pneumococcal nasopharyngeal colonization in HIV-infected and HIV-uninfected African children. Vaccine. 2013 Sep 13; 31(40):4421-7.
    View in: PubMed
    Score: 0,353
  15. Acquisition of Streptococcus pneumoniae in pneumococcal conjugate vaccine-naïve South African children and their mothers. Pediatr Infect Dis J. 2013 May; 32(5):e192-205.
    View in: PubMed
    Score: 0,348
  16. Inferior quantitative and qualitative immune responses to pneumococcal conjugate vaccine in infants with nasopharyngeal colonization by Streptococcus pneumoniae during the primary series of immunization. Vaccine. 2011 Sep 16; 29(40):6994-7001.
    View in: PubMed
    Score: 0,308
  17. Review on the immunogenicity and safety of PCV-13 in infants and toddlers. Expert Rev Vaccines. 2011 Jul; 10(7):951-80.
    View in: PubMed
    Score: 0,307
  18. The impact of antiretroviral treatment on the burden of invasive pneumococcal disease in South African children: a time series analysis. AIDS. 2011 Feb 20; 25(4):453-62.
    View in: PubMed
    Score: 0,299
  19. Role of Streptococcus pneumoniae in hospitalization for acute community-acquired pneumonia associated with culture-confirmed Mycobacterium tuberculosis in children: a pneumococcal conjugate vaccine probe study. Pediatr Infect Dis J. 2010 Dec; 29(12):1099-04.
    View in: PubMed
    Score: 0,295
  20. Long-term effect of pneumococcal conjugate vaccine on nasopharyngeal colonization by Streptococcus pneumoniae--and associated interactions with Staphylococcus aureus and Haemophilus influenzae colonization--in HIV-Infected and HIV-uninfected children. J Infect Dis. 2007 Dec 01; 196(11):1662-6.
    View in: PubMed
    Score: 0,238
  21. Long-term immunogenicity and efficacy of a 9-valent conjugate pneumococcal vaccine in human immunodeficient virus infected and non-infected children in the absence of a booster dose of vaccine. Vaccine. 2007 Mar 22; 25(13):2451-7.
    View in: PubMed
    Score: 0,220
  22. Pneumococcal coinfection with human metapneumovirus. J Infect Dis. 2006 May 01; 193(9):1236-43.
    View in: PubMed
    Score: 0,213
  23. A role for Streptococcus pneumoniae in virus-associated pneumonia. Nat Med. 2004 Aug; 10(8):811-3.
    View in: PubMed
    Score: 0,189
  24. Geographical migration and fitness dynamics of Streptococcus pneumoniae. Nature. 2024 Jul; 631(8020):386-392.
    View in: PubMed
    Score: 0,189
  25. Bacterial nasopharyngeal colonisation in children in South Africa before and during the COVID-19 pandemic: an observational study. Lancet Microbe. 2024 01; 5(1):e34-e42.
    View in: PubMed
    Score: 0,181
  26. Optimization of a high-throughput nanofluidic real-time PCR to detect and quantify of 15 bacterial species and 92 Streptococcus pneumoniae serotypes. Sci Rep. 2023 03 21; 13(1):4588.
    View in: PubMed
    Score: 0,173
  27. Population genomics of pneumococcal carriage in South Africa following the introduction of the 13-valent pneumococcal conjugate vaccine (PCV13) immunization. Microb Genom. 2022 06; 8(6).
    View in: PubMed
    Score: 0,163
  28. High-throughput nanofluidic real-time PCR to discriminate Pneumococcal Conjugate Vaccine (PCV)-associated serogroups 6, 18, and 22 to serotypes using modified oligonucleotides. Sci Rep. 2021 12 09; 11(1):23728.
    View in: PubMed
    Score: 0,158
  29. Bacterial nasopharyngeal carriage following infant immunization with pneumococcal conjugate vaccines according to a 2+1 schedule in children in South Africa: an exploratory analysis of two clinical trials. Expert Rev Vaccines. 2020 12; 19(12):1177-1189.
    View in: PubMed
    Score: 0,148
  30. Impact of human immunodeficiency virus type 1 on the disease spectrum of Streptococcus pneumoniae in South African children. Pediatr Infect Dis J. 2000 Dec; 19(12):1141-7.
    View in: PubMed
    Score: 0,147
  31. Upper airways colonisation of Streptococcus pneumoniae in adults aged 60 years and older: A systematic review of prevalence and individual participant data meta-analysis of risk factors. J Infect. 2020 10; 81(4):540-548.
    View in: PubMed
    Score: 0,143
  32. Visualizing variation within Global Pneumococcal Sequence Clusters (GPSCs) and country population snapshots to contextualize pneumococcal isolates. Microb Genom. 2020 05; 6(5).
    View in: PubMed
    Score: 0,141
  33. A mosaic tetracycline resistance gene tet(S/M) detected in an MDR pneumococcal CC230 lineage that underwent capsular switching in South Africa. J Antimicrob Chemother. 2020 03 01; 75(3):512-520.
    View in: PubMed
    Score: 0,140
  34. Streptococcus pneumoniae colonization in pneumococcal vaccine-naïve human immunodeficiency virus-exposed infected and -uninfected South African children. Medicine (Baltimore). 2020 Feb; 99(9):e19353.
    View in: PubMed
    Score: 0,139
  35. Genomic differences among carriage and invasive nontypeable pneumococci circulating in South Africa. Microb Genom. 2019 10; 5(10).
    View in: PubMed
    Score: 0,136
  36. Pneumococcal conjugate vaccine--prospects for intervention in children. Semin Respir Infect. 1999 Sep; 14(3):285-94.
    View in: PubMed
    Score: 0,135
  37. Putative novel cps loci in a large global collection of pneumococci. Microb Genom. 2019 07; 5(7).
    View in: PubMed
    Score: 0,133
  38. Joint sequencing of human and pathogen genomes reveals the genetics of pneumococcal meningitis. Nat Commun. 2019 05 15; 10(1):2176.
    View in: PubMed
    Score: 0,132
  39. International genomic definition of pneumococcal lineages, to contextualise disease, antibiotic resistance and vaccine impact. EBioMedicine. 2019 May; 43:338-346.
    View in: PubMed
    Score: 0,132
  40. The relative invasive disease potential of Streptococcus pneumoniae among children after PCV introduction: A systematic review and meta-analysis. J Infect. 2018 11; 77(5):368-378.
    View in: PubMed
    Score: 0,125
  41. Global Distribution of Invasive Serotype 35D Streptococcus pneumoniae Isolates following Introduction of 13-Valent Pneumococcal Conjugate Vaccine. J Clin Microbiol. 2018 07; 56(7).
    View in: PubMed
    Score: 0,124
  42. Evaluation of the association of pneumococcal conjugate vaccine immunization and density of nasopharyngeal bacterial colonization using a multiplex quantitative polymerase chain reaction assay. Vaccine. 2018 05 31; 36(23):3278-3285.
    View in: PubMed
    Score: 0,123
  43. Immunogenicity of 13-valent pneumococcal conjugate vaccine among children with underlying medical conditions. Vaccine. 2017 08 03; 35(34):4321-4329.
    View in: PubMed
    Score: 0,116
  44. Density of Upper Respiratory Colonization With Streptococcus pneumoniae and Its Role in the Diagnosis of Pneumococcal Pneumonia Among Children Aged <5 Years in the PERCH Study. Clin Infect Dis. 2017 Jun 15; 64(suppl_3):S317-S327.
    View in: PubMed
    Score: 0,116
  45. Detection of Pneumococcal DNA in Blood by Polymerase Chain Reaction for Diagnosing Pneumococcal Pneumonia in Young Children From Low- and Middle-Income Countries. Clin Infect Dis. 2017 Jun 15; 64(suppl_3):S347-S356.
    View in: PubMed
    Score: 0,116
  46. Evaluation of Pneumococcal Load in Blood by Polymerase Chain Reaction for the Diagnosis of Pneumococcal Pneumonia in Young Children in the PERCH Study. Clin Infect Dis. 2017 Jun 15; 64(suppl_3):S357-S367.
    View in: PubMed
    Score: 0,116
  47. Effectiveness of the 13-valent pneumococcal conjugate vaccine against invasive pneumococcal disease in South African children: a case-control study. Lancet Glob Health. 2017 03; 5(3):e359-e369.
    View in: PubMed
    Score: 0,113
  48. Multiplex Urinary Antigen Detection for 13 Streptococcus pneumoniae Serotypes Improves Diagnosis of Pneumococcal Pneumonia in South African HIV-Infected Adults. J Clin Microbiol. 2017 01; 55(1):302-312.
    View in: PubMed
    Score: 0,112
  49. Epidemiology of Serotype 1 Invasive Pneumococcal Disease, South Africa, 2003-2013. Emerg Infect Dis. 2016 Feb; 22(2):261-70.
    View in: PubMed
    Score: 0,105
  50. The potential impact of pneumococcal conjugate vaccine in Africa: Considerations and early lessons learned from the South African experience. Hum Vaccin Immunother. 2016; 12(2):314-25.
    View in: PubMed
    Score: 0,105
  51. Assessing the impact of pneumococcal conjugate vaccines on invasive pneumococcal disease using polymerase chain reaction-based surveillance: an experience from South Africa. BMC Infect Dis. 2015 Oct 26; 15:450.
    View in: PubMed
    Score: 0,103
  52. Streptococcus pneumoniae Serotypes and Mortality in Adults and Adolescents in South Africa: Analysis of National Surveillance Data, 2003 - 2008. PLoS One. 2015; 10(10):e0140185.
    View in: PubMed
    Score: 0,103
  53. Immunogenicity and safety of the 13-valent pneumococcal conjugate vaccine in HIV-infected individuals naive to pneumococcal vaccination. AIDS. 2015 Jul 17; 29(11):1345-54.
    View in: PubMed
    Score: 0,101
  54. Longitudinal study on Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus nasopharyngeal colonization in HIV-infected and -uninfected infants vaccinated with pneumococcal conjugate vaccine. Vaccine. 2015 May 28; 33(23):2662-9.
    View in: PubMed
    Score: 0,100
  55. Genomic load from sputum samples and nasopharyngeal swabs for diagnosis of pneumococcal pneumonia in HIV-infected adults. J Clin Microbiol. 2014 Dec; 52(12):4224-9.
    View in: PubMed
    Score: 0,096
  56. Pneumococcal colonisation density: a new marker for disease severity in HIV-infected adults with pneumonia. BMJ Open. 2014 Aug 11; 4(8):e005953.
    View in: PubMed
    Score: 0,095
  57. Dynamics of pneumococcal transmission in vaccine-naive children and their HIV-infected or HIV-uninfected mothers during the first 2 years of life. Am J Epidemiol. 2013 Dec 01; 178(11):1629-37.
    View in: PubMed
    Score: 0,090
  58. Respiratory viral and pneumococcal coinfection of the respiratory tract: implications of pneumococcal vaccination. Expert Rev Respir Med. 2012 Aug; 6(4):451-65.
    View in: PubMed
    Score: 0,083
  59. The Pneumonia Etiology Research for Child Health Project: a 21st century childhood pneumonia etiology study. Clin Infect Dis. 2012 Apr; 54 Suppl 2:S93-101.
    View in: PubMed
    Score: 0,081
  60. Epidemiology of acute osteoarticular sepsis in a setting with a high prevalence of pediatric HIV infection. J Pediatr Orthop. 2012 Mar; 32(2):215-9.
    View in: PubMed
    Score: 0,080
  61. Safety, immunogenicity and efficacy of pneumococcal conjugate vaccine in HIV-infected individuals. Hum Vaccin Immunother. 2012 Feb; 8(2):161-73.
    View in: PubMed
    Score: 0,080
  62. Use of a rapid test of pneumococcal colonization density to diagnose pneumococcal pneumonia. Clin Infect Dis. 2012 Mar 01; 54(5):601-9.
    View in: PubMed
    Score: 0,079
  63. Conserved mutations in the pneumococcal bacteriocin transporter gene, blpA, result in a complex population consisting of producers and cheaters. mBio. 2011; 2(5).
    View in: PubMed
    Score: 0,078
  64. An evaluation of emerging vaccines for childhood pneumococcal pneumonia. BMC Public Health. 2011 Apr 13; 11 Suppl 3:S26.
    View in: PubMed
    Score: 0,076
  65. Use of 2 pneumococcal common protein real-time polymerase chain reaction assays in healthy children colonized with Streptococcus pneumoniae. Diagn Microbiol Infect Dis. 2011 Aug; 70(4):452-4.
    View in: PubMed
    Score: 0,075
  66. An unusual pneumococcal sequence type is the predominant cause of serotype 3 invasive disease in South Africa. J Clin Microbiol. 2010 Jan; 48(1):184-91.
    View in: PubMed
    Score: 0,068
  67. Novel approaches to the identification of Streptococcus pneumoniae as the cause of community-acquired pneumonia. Clin Infect Dis. 2008 Dec 01; 47 Suppl 3:S202-6.
    View in: PubMed
    Score: 0,064
  68. Serotype 6C is associated with penicillin-susceptible meningeal infections in human immunodeficiency virus (HIV)-infected adults among invasive pneumococcal isolates previously identified as serotype 6A in South Africa. Int J Antimicrob Agents. 2008 Nov; 32 Suppl 1:S66-70.
    View in: PubMed
    Score: 0,063
  69. Pneumococcal vaccination in developing countries. Lancet. 2006 Jun 10; 367(9526):1880-2.
    View in: PubMed
    Score: 0,054
  70. Long-term effect of pneumococcal conjugate vaccines on invasive pneumococcal disease incidence among people of all ages from national, active, laboratory-based surveillance in South Africa, 2005-19: a cohort observational study. Lancet Glob Health. 2024 Sep; 12(9):e1470-e1484.
    View in: PubMed
    Score: 0,048
  71. Immunogenicity and seroefficacy of pneumococcal conjugate vaccines: a systematic review and network meta-analysis. Health Technol Assess. 2024 Jul; 28(34):1-109.
    View in: PubMed
    Score: 0,047
  72. Characterization of bacterial and viral pathogens in the respiratory tract of children with HIV-associated chronic lung disease: a case-control study. BMC Infect Dis. 2024 Jun 26; 24(1):637.
    View in: PubMed
    Score: 0,047
  73. Gender as a risk factor for both antibiotic resistance and infection with pediatric serogroups/serotypes, in HIV-infected and -uninfected adults with pneumococcal bacteremia. J Infect Dis. 2004 Jun 01; 189(11):1996-2000.
    View in: PubMed
    Score: 0,047
  74. Post-mortem investigation of deaths due to pneumonia in children aged 1-59 months in sub-Saharan Africa and South Asia from 2016 to 2022: an observational study. Lancet Child Adolesc Health. 2024 Mar; 8(3):201-213.
    View in: PubMed
    Score: 0,046
  75. Nanofluidic qPCR unable to detect and serotype Streptococcus pneumoniae in urine samples of hospitalized South African patients with community-acquired pneumonia. Sci Rep. 2023 12 04; 13(1):21332.
    View in: PubMed
    Score: 0,045
  76. A phase 3 study of safety and immunogenicity of V114, a 15-valent pneumococcal conjugate vaccine, followed by 23-valent pneumococcal polysaccharide vaccine, in children with HIV. AIDS. 2023 07 01; 37(8):1227-1237.
    View in: PubMed
    Score: 0,043
  77. Mortality in children aged <5 years with severe acute respiratory illness in a high HIV-prevalence urban and rural areas of South Africa, 2009-2013. PLoS One. 2021; 16(8):e0255941.
    View in: PubMed
    Score: 0,039
  78. Upper Respiratory Tract Co-detection of Human Endemic Coronaviruses and High-density Pneumococcus Associated With Increased Severity Among HIV-Uninfected Children Under 5 Years Old in the PERCH Study. Pediatr Infect Dis J. 2021 06 01; 40(6):503-512.
    View in: PubMed
    Score: 0,038
  79. Impact of 13-valent pneumococcal conjugate vaccine on laboratory-confirmed pneumococcal meningitis and purulent meningitis among children ?5 years in Cameroon, 2011-2018. PLoS One. 2021; 16(4):e0250010.
    View in: PubMed
    Score: 0,038
  80. Emergence of drug resistance. Impact on bacterial meningitis. Infect Dis Clin North Am. 1999 Sep; 13(3):637-46, vii.
    View in: PubMed
    Score: 0,034
  81. Imputing the Direct and Indirect Effectiveness of Childhood Pneumococcal Conjugate Vaccine Against Invasive Pneumococcal Disease by Surveying Temporal Changes in Nasopharyngeal Pneumococcal Colonization. Am J Epidemiol. 2017 Aug 15; 186(4):435-444.
    View in: PubMed
    Score: 0,029
  82. The Effect of Antibiotic Exposure and Specimen Volume on the Detection of Bacterial Pathogens in Children With Pneumonia. Clin Infect Dis. 2017 Jun 15; 64(suppl_3):S368-S377.
    View in: PubMed
    Score: 0,029
  83. Etiology of Acute Otitis Media in Children Less Than 5 Years of Age: A Pooled Analysis of 10 Similarly Designed Observational Studies. Pediatr Infect Dis J. 2017 03; 36(3):274-281.
    View in: PubMed
    Score: 0,028
  84. HIV Infection and the Epidemiology of Invasive Pneumococcal Disease (IPD) in South African Adults and Older Children Prior to the Introduction of a Pneumococcal Conjugate Vaccine (PCV). PLoS One. 2016; 11(2):e0149104.
    View in: PubMed
    Score: 0,026
  85. Effects of vaccination on invasive pneumococcal disease in South Africa. N Engl J Med. 2014 Nov 13; 371(20):1889-99.
    View in: PubMed
    Score: 0,024
  86. Effectiveness of 7-valent pneumococcal conjugate vaccine against invasive pneumococcal disease in HIV-infected and -uninfected children in south africa: a matched case-control study. Clin Infect Dis. 2014 Sep 15; 59(6):808-18.
    View in: PubMed
    Score: 0,024
  87. High nasopharyngeal pneumococcal density, increased by viral coinfection, is associated with invasive pneumococcal pneumonia. J Infect Dis. 2014 Nov 15; 210(10):1649-57.
    View in: PubMed
    Score: 0,023
  88. HIV and influenza virus infections are associated with increased blood pneumococcal load: a prospective, hospital-based observational study in South Africa, 2009-2011. J Infect Dis. 2014 Jan 01; 209(1):56-65.
    View in: PubMed
    Score: 0,022
  89. Epidemiology of invasive pneumococcal disease in the pre-conjugate vaccine era: South Africa, 2003-2008. Vaccine. 2013 Aug 28; 31(38):4200-8.
    View in: PubMed
    Score: 0,022
  90. Estimating the protective concentration of anti-pneumococcal capsular polysaccharide antibodies. Vaccine. 2007 May 10; 25(19):3816-26.
    View in: PubMed
    Score: 0,014
  91. HIV and pneumococcal disease. Curr Opin Infect Dis. 2007 Feb; 20(1):11-5.
    View in: PubMed
    Score: 0,014
  92. Guideline for the management of upper respiratory tract infections. S Afr Med J. 2004 Jun; 94(6 Pt 2):475-83.
    View in: PubMed
    Score: 0,012
  93. A trial of a 9-valent pneumococcal conjugate vaccine in children with and those without HIV infection. N Engl J Med. 2003 Oct 02; 349(14):1341-8.
    View in: PubMed
    Score: 0,011
Connection Strength

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Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.